Methylococcus sp. EFPC2: JWZ97_17770
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Entry
JWZ97_17770 CDS
T10116
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
meef Methylococcus sp. EFPC2
Pathway
meef00230
Purine metabolism
meef01100
Metabolic pathways
meef01110
Biosynthesis of secondary metabolites
Module
meef_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
meef00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
JWZ97_17770 (purL)
Enzymes [BR:
meef01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
JWZ97_17770 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QSA97025
UniProt:
A0A974ZP78
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Position
4135462..4139340
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AA seq
1292 aa
AA seq
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MIFKLSGARALSSFRLEKLLGELRGVEPGIAELHASFVHFVETSRELAPPELAVLEPLLD
YGAKAEPCAFGGEYFLVVPRLGTLSPWSSKATDIARHCGLDAVLRIERGIEYCLRTEVEL
SHSRREAVKALLHDRMTQVVLGRGQHDQIFRHQPPAPLDYVPLLQEGRWALVKANSGLGL
ALSEDELDYLEQSYTALNRNPTDVELMMFAQANSEHCRHKIFNASWRIDGEEQAESLFGM
IRNTARKSPAGIISAYKDNASIIEGPKAQVFLRDPQSLEYGYVEESAHILMKVETHNHPT
AISPHPGAATGSGGEIRDEGATGRGSWTKAGLTGFTVSDLRIPGYVQPWESDHGKPGRIA
SALDIMLEGPVGGAAFNNEFGRPNIAGYFRTFEQRDPQGEGLWGYHKPIMIAGGMGQIRP
MHTAKEGIPAGSAIVVLGGPAMLIGLGGGAASSQASGESAESLDFASVQRENPEMQRRAQ
EVINRCVALGTANPIVSIHDVGAGGLSNAVPEIIHDAGRGGRFELRRVPNDEPSMSPLQI
WCNEAQERYVLAIAPESVALFDEFCRRERCPYAVLGHATDEEQLILSDEVFGNRPINIPM
SLLFGKPPKMARDVRRVAPSLPELDLRTVEIADAARRVLAFPAVADKSFLIHIGDRSVGG
LVARDQMVGPWQVPVADVGVTASGFHAYTGEAMAMGERTPLAVIDAPASGRMAIAEALTN
LAAARIGRLGDVKLSANWMAAAGAPGEDARLYDTVKAVGLELCPDLGIAIPVGKDSLSMK
TVWREGERENNMTSPLSLIVTAFAPVLDVRRTLTPELKLNAGPSRLVLIDLGFGRNRLGG
SVLAQVYGQIGNRAPDLDDPVRLKAFFAAIQSLNADGLLLAYHDRSDGGLWATLCEMAFA
ARSGVELSLDGLGDDPYAALFNEELGALIQVAEDKLAEVLERLKQAGLEGAVHVVGAPRA
DRRIVVTRQGGVWYQEARSALQSLWSETSYRMQALRDHPECARSEHDAVADDLDPGRYSR
LTFDLNEDVAAPFLNLSRPRVAILREQGVNGHVEMAAAFERAGFASVDVHMNDLVVGTVS
LADFKGLAACGGFSFGDVLGAGGGWAKSILFNEHLYDEFAAFFSRSDSFGLGVCNGCQMM
AHLRELVPGAGLWPHFARNTSEQFEARVVLVEVLESPSLFFAGMAGSVLPVVVAHGEGRA
DFRADPAQAVERRQAALRYVDHYGKPTETFPYNPNGSPLGITALTNEDGRFTIMMPHPER
CFRSVQNSWRSAEWGEYGPWMRMFRNARAWVG
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atgatcttcaagttaagcggcgcgcgcgccctctcctcattccgcctggaaaaactgctg
ggcgaactcaggggcgtcgagcccggtatcgccgaactgcatgccagcttcgtgcatttc
gtcgaaacctcgcgcgaactggccccgcccgagctggccgtgctggagcccctgctcgat
tacggcgccaaggccgaaccctgcgccttcggcggggaatatttcctggtcgtgccccgg
ctcggcaccctctcgccctggtccagcaaggcgaccgacatcgcccggcattgcggcctg
gatgccgtgctgcgcatcgagcgcgggatcgagtattgcctgaggaccgaggtcgagctc
agccattccaggcgcgaagccgtcaaggccttgttgcacgaccgcatgacccaggtcgtg
ctgggccgcggccagcacgatcagatcttccgtcaccagccccctgcgccgcttgactac
gtgccactgctgcaggaagggcgctgggccctggtcaaggccaacagcgggttaggcctg
gccttgtcggaggacgagctggactatctcgaacaaagctacaccgcgctgaaccgcaat
cccaccgatgtggaattgatgatgttcgcccaggccaactcggaacattgccgccacaag
atattcaatgcgtcctggcgcatcgacggcgaggagcaggccgaatcgctgttcggcatg
atccgcaacaccgcgcgcaagagtcccgccggcatcatttcggcctacaaggacaatgcc
tccatcatcgaagggcccaaggcccaagtgtttctgcgcgacccgcagagtctggaatac
ggctatgtggaggagtccgcccacatcctgatgaaggtggagacccacaatcatcccacc
gctatttcgccacatccgggcgcggccaccgggtccggcggcgagatccgcgacgaaggc
gcgaccgggcggggatcgtggaccaaggccggattgaccggcttcacggtgtccgatctg
cgcatcccgggttatgtccagccgtgggaaagcgatcacggcaagcccggccgcatcgcc
tcggcgctggacatcatgctggaaggtccggtcggcggcgcggccttcaacaacgagttc
ggccggcccaacatcgccggctatttccgcaccttcgagcagcgcgacccgcaaggcgaa
gggctgtggggttaccacaaacccatcatgatcgccggcggcatgggccagatccggccc
atgcatacggccaaggagggcataccggccggctccgccatcgtggtgctgggcgggccg
gccatgctcatcggcctgggcggcggcgccgcgtcgtcgcaagcgtccggcgagagcgcc
gagtcgctcgatttcgcttccgtccagcgcgagaatcccgagatgcagcggcgcgcgcag
gaggtcatcaaccgctgcgtagccctgggtacggccaatcccatcgtctccatacacgac
gtcggtgccggcgggctttccaacgcggtgccggaaatcatccacgatgcgggccgtggc
ggccgcttcgaattgcgccgggtgccgaacgacgagccgagcatgtcgcccctgcaaatc
tggtgcaacgaagcccaggaacgctatgtgctggccatcgcgcccgaatcggtcgcgttg
ttcgatgagttttgccggcgcgagcgttgtccttacgcggtgcttggccatgccaccgac
gaggagcaacttatcctcagcgacgaagtgttcggcaaccggcccatcaacatcccgatg
tccctgctgttcggcaagccgcccaagatggcccgcgacgtgcggcgcgttgctcccagc
ctgcccgagctggacctgcgcaccgtcgagatcgccgatgccgcgcgccgggtgctggct
ttccccgccgtggcggacaagagctttttgatccacatcggcgaccgctcggtgggcggc
ctggtggcccgcgaccagatggtcggcccctggcaggtaccggtcgccgacgtcggcgtc
acggcgtcgggtttccacgcctataccggcgaggccatggccatgggcgagcggacgccc
ctggccgtgatcgacgccccggcctccggccgcatggccatcgccgaggcgctgaccaac
ctggctgcggcgcgtattggacgactgggcgacgtcaagctttcggccaactggatggcg
gccgccggcgcgcccggcgaagacgcgcggctgtacgacaccgtcaaggcggtcggcctg
gaattgtgtccggatctgggcatcgccatccccgtcggcaaggattcgctgtccatgaag
accgtatggagggagggggagcgcgaaaataacatgacctcgccgctttcgctcatcgtc
acggccttcgccccggtgctggacgtgcgccggaccctcacaccggagctgaagctgaat
gccggcccgagccgcctggtgctgatcgatctcgggttcggacgcaaccgtctgggcggt
tcggtgctggcccaggtctacgggcagattggcaaccgggctcccgacctggatgatccc
gtccgcctcaaggcgtttttcgcggctatccagtcgctcaatgcggacggcttgctgctg
gcctaccacgatcgctccgacggcggtctgtgggccaccctgtgcgagatggccttcgcc
gcccgcagcggtgtggagctcagcctggacgggctgggcgacgacccttacgcggcgctg
ttcaacgaggaattgggcgcgctgatccaggtcgccgaggacaagctcgccgaggtgctg
gaaaggctgaaacaggccggtctggagggtgccgtccatgtcgtcggcgcgccgcgcgcc
gaccgccgcatcgtggtgacccggcagggcggcgtctggtaccaggaggcgcgaagcgct
ctgcagagcctgtggtcggaaaccagctaccgcatgcaggcgctgcgcgatcatccggag
tgcgcgcgcagcgaacatgacgcggtggccgacgatctcgatcccggtcgctacagtcgt
ctgactttcgatctcaacgaagacgtggcggcgcctttcctgaatctgtcgcgcccgcgc
gtggccatcctgcgtgaacagggcgtcaacggccatgtcgaaatggcggcggccttcgaa
cgcgccggtttcgccagcgtcgacgtgcacatgaacgacctggtggtcggtacggtcagc
ctcgccgatttcaaggggctggccgcctgcggcggcttttccttcggcgacgtgctgggg
gcgggcggcggttgggccaagtccatcctgttcaacgagcatttgtacgacgagttcgcc
gcgttcttctcgcgctccgacagcttcggcctgggcgtctgcaacggctgccagatgatg
gcccatttgcgcgaactggtgccgggggcgggcctgtggccgcatttcgcccgcaacacg
tcggaacagtttgaagcccgcgtggtcctggtcgaggtgctcgaatcgccctcgctgttc
ttcgccggcatggcaggttcggttctgccggtggtcgtcgcgcacggcgagggccgggcg
gatttccgcgccgatccggcccaggcggtcgagcgccggcaggcagctttgcgctatgtc
gatcactacggcaagccgaccgagaccttcccgtacaaccccaacggatcgccgctgggc
atcaccgcgctgaccaacgaggatggccgattcaccatcatgatgccgcatccggagcgt
tgtttccgtagcgtgcagaactcctggcgttcggccgaatggggcgaatacgggccgtgg
atgcgcatgttccgcaacgcgcgggcctgggtgggctag
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