KEGG T10319: JWZ98

Methylomonas sp. EFPC1: JWZ98_11020

Entry

JWZ98_11020       CDS       T10319

Symbol

folC

Name

(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase

K11754

dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

Organism

meep Methylomonas sp. EFPC1

Pathway

meep00790

Folate biosynthesis

meep01100

Metabolic pathways

meep01240

Biosynthesis of cofactors

Module

meep_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Brite

KEGG Orthology (KO) [BR:meep00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    JWZ98_11020 (folC)
Enzymes [BR:meep01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     JWZ98_11020 (folC)
    6.3.2.17  tetrahydrofolate synthase
     JWZ98_11020 (folC)

SSDB

Motif

Pfam:

Mur_ligase_C Mur_ligase_M nSTAND_NTPase5 DUF3923

Other DBs

NCBI-ProteinID:

QSB03408

LinkDB

Position

2358436..2359701

AA seq 421 aa
MTRFDSLQAWLDWQEKLHPRPIDLGLGRVAGVYRQLNPEQKKPLTITVAGTNGKGSCVAF
LEAIYRAAGYRVGAYTSPHILRYNERIRIDGVPVEDALICDAFTRIDGARGETSLSYFEF
GTLAALGIFAEADLDIQLLEVGLGGRLDAVNIIDPDAAIVTTIALDHVDWLGHTEEAIGR
EKAGIFRSGVAAIIGDAQAPRSVVEVASQVGAIALQMDSEFSYQKQRDSWEWRSADKQID
RLPAPAFKGEHQYRNASAAIMAINTLQPILAVSDDAIRQGLESARLSGRFQLIAGAPRIL
LDVGHNPQAVQTLINYLSEYFPEIRIHAVFAMMRDKDIAGVLNMMRDKVATWYLAPLANP
RAATPDMLETIFQQQGLDNVRSGFTDFTEAFQAARQNTGQDDLLLIFGSFFLVSEYLSKF
S

NT seq 1266 nt +upstreamnt +downstreamnt
atgacacgttttgattcgctgcaagcctggttggattggcaggaaaaactacatcctcgg
cctatcgatttagggttgggaagagttgccggcgtatatcggcagcttaatcccgaacaa
aaaaaaccgctaaccatcaccgttgccggtaccaacggcaagggttcctgcgtggcgttt
ctggaagcgatttatcgggccgcgggctaccgggttggcgcctacacatcgccgcatatt
ttgcgctataacgaacgcattcgtattgatggtgtgccggtcgaggatgctttgatttgc
gatgcttttacccgcattgatggggcgcgcggcgagaccagtttgagctatttcgagttt
ggcacgttggcagccttgggtattttcgccgaggcagatctggatattcagttactggaa
gtcggtttaggcggcagacttgatgcggtgaatattattgaccccgatgcagcgattgtg
acgacgatagcacttgatcatgtggattggctggggcataccgaagaagccatcggtcgg
gaaaaagccggcatttttagatccggtgtggcggctataatcggcgatgcgcaagcgcca
cgctcagtagtcgaagtagcctcgcaagtcggagccattgcgctgcaaatggacagcgaa
ttcagttatcaaaaacagcgtgatagctgggaatggcgctctgcggataagcaaatagat
cgcttgccggcgccggcgtttaagggcgaacaccaatatcgaaatgcttccgcggcgata
atggctataaacaccctacagccgatattagcggtcagtgacgatgcaattcggcaaggc
ttggaaagtgcccggctatcaggacgttttcagttgattgccggcgcgccgcgcattttg
cttgatgtcggacacaacccgcaggctgtgcaaacattaatcaactatttgtctgaatac
ttccccgagatcagaatacatgcagtttttgcgatgatgcgggataaagatattgccggc
gtattgaacatgatgcgcgacaaagtggctacgtggtatttagcgccacttgctaatcct
cgcgctgcaactccggatatgttagaaaccatttttcagcaacaaggcctggataatgtc
cgtagcggttttaccgattttaccgaggcatttcaagccgcccggcaaaataccggacag
gacgacttgcttttgatttttggttctttttttctagtatccgaatatttatcgaaattt
tcttag

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