Methanobacterium lacus: Metbo_0066
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Entry
Metbo_0066 CDS
T01437
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mel
Methanobacterium lacus
Pathway
mel00290
Valine, leucine and isoleucine biosynthesis
mel00620
Pyruvate metabolism
mel01100
Metabolic pathways
mel01110
Biosynthesis of secondary metabolites
mel01210
2-Oxocarboxylic acid metabolism
mel01230
Biosynthesis of amino acids
Module
mel_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mel00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Metbo_0066
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Metbo_0066
Enzymes [BR:
mel01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Metbo_0066
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
ADZ08319
UniProt:
F0T6T6
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All DBs
Position
complement(61832..63349)
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AA seq
505 aa
AA seq
DB search
MYIETVKQTMNLPDTVKILDTTLRDGEQTPGVALTVDEKIRIAKKLDKLGVNTMEVGFPA
ASDGEVRATKEILKLELDSRVCGLARPLRVDLDAAIDCGVDYIHTFIGTSPLHREYKLKM
DKEEILNKSVEGVEYIKDHGITAEFSAEDATRTEFDYLKEVYLAVEDAGADFINVPDTVG
VMIPSSMNYLITELKKILKTPISVHCHDDFGLAVANSLSAVEAGASQVHSTINGLGERAG
NASLEEVVMALTSQYNIKTSIDTKLLVDTSEFVSRITGIKMPPNKAIIGENAFAHEAGIH
VHGVLQNAETYEPITPEMVGHTRRIVLGKHTGANAIKAKLDEYGIELNEDQFIRVFDQVK
RLGDKGKCVTDADLKAMSETVLGKAHKEIVKLEGFSVMTGDNVMPTATVKLDINGKVKTA
AKTGVGPVDAAINAIQSLVGETADIELKEYNIEAITGGTNALAEVFVIMGDKKGNKATGR
STTDDVVMASVEAVLDSINKILIER
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgtacatagaaacagtcaaacagactatgaatcttccagataccgttaaaattctggac
actaccctaagggatggggaacaaacacctggagtagccctaactgtagatgaaaagata
agaatagctaaaaagttagataaattgggtgttaacaccatggaagttggatttccagct
gcatcagatggtgaagttagagctacaaaagaaattttaaaacttgaacttgactcccga
gtttgtggtttggcaagacctttacgtgttgatttagatgctgcaatagactgtggtgtg
gattacattcacacgtttatagggacttctccattacaccgagagtacaagttaaaaatg
gataaggaagaaattttaaataagtctgtagagggtgttgaatacataaaggatcatgga
ataactgctgaattttcagcagaagatgctacacgtactgaatttgattatcttaaagaa
gtgtatctggctgttgaggatgctggtgcagatttcataaacgtaccagatacagttgga
gtaatgatcccgtcttcaatgaactatttaattactgaactgaagaaaatattgaaaact
cccatcagtgttcattgtcatgatgattttgggctggctgttgcaaattccctgagtgcg
gtagaagcaggtgcaagtcaagtgcattcaaccataaatggattaggggagcgggcagga
aatgcttctttagaagaggttgtaatggctttaacatctcaatataatattaaaacatct
atagatacaaaactattagttgatacctctgaatttgtatcaaggataactggtattaaa
atgcctccaaacaaggcaataattggggagaatgcatttgcacacgaggccggaatccat
gtccatggtgtccttcaaaatgcagaaacttacgaaccaatcacaccagaaatggttggc
cataccagaagaatagtccttggaaaacacacaggggcaaatgctataaaggccaaactt
gatgagtatggcattgaactcaatgaagatcagttcataagggtttttgatcaggttaaa
aggcttggagacaagggtaaatgcgtaacagatgctgatctaaaggcaatgtccgagact
gtgcttggaaaggcccacaaagaaattgtcaaactcgagggcttctcagtaatgactggt
gataatgtaatgccaacagcaacagtaaagcttgatatcaacggcaaagttaaaacagct
gcaaaaacaggagtaggtccagtagacgcagctataaatgcaatacaaagcttagtaggg
gagacagcagatattgaactcaaagaatataatattgaagcaataactggtggaactaat
gctctagctgaagtatttgttattatgggtgataagaagggcaacaaggcaactggaaga
tcaacaacagatgacgtggtcatggcaagtgttgaagcagttttagattcaattaacaag
atacttattgaacgttaa
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