Metabacillus endolithicus: MVE64_14605
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Entry
MVE64_14605 CDS
T09915
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
menl
Metabacillus endolithicus
Pathway
menl00300
Lysine biosynthesis
menl00550
Peptidoglycan biosynthesis
menl01100
Metabolic pathways
menl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
menl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MVE64_14605
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MVE64_14605
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MVE64_14605
Enzymes [BR:
menl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MVE64_14605
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UPG61869
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Position
2834932..2836296
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AA seq
454 aa
AA seq
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MITRTLLDVQNMVNGEGLEEKYQHVEISGVTTDSRNVENDNLFFPLVGDVFNGHEFVDKA
ISNGAKAVIWQKSEKNPPKEVPIILVEDTLVALQALATAYINELPNLKIIGITGSNGKTT
TKDMVAAILETTYKVHKTQGNFNNHIGLPLTVLSMSEDTEIAVLEMGMSGKGEIELLSEI
AHPDVAVITNIGEAHLMDLGSREGIAEAKLEITKGLKKDGLFIFHGDEPLLQERVPGLSL
KTTTFGEASSNDYYPAKIIQEPTGTLFEVNKEEYFIPVLGKHNVWNALAAYAVADYYGVE
KDAIKKGFSSMKLTGMRLELIQAKNGASIINDAYNASPTSMLAAIDLIENLKDFDQKIVV
LGDMLELGDDEVEYHQQVGREIKQNNISHIFTYGKLGKEIAKGAKENQSVDTVHHYDQKD
ELIKHLQSIVKEKDIVLVKASRGMKLEEVVNSIV
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgattacaagaacactacttgatgtacaaaacatggtgaatggagaaggattagaagaa
aaatatcaacacgttgaaatttcaggcgtaacaactgattcacgtaatgttgaaaatgat
aatttattttttccacttgttggtgacgtattcaatgggcatgagttcgttgacaaagca
ataagtaacggagcaaaagcagttatttggcagaaatccgaaaaaaaccctccaaaagaa
gtgccaatcattttagttgaagatactttagtggcgcttcaagctcttgcaacagcatat
attaatgaattacctaacctgaaaattatcggtattacaggtagtaacggtaaaacaaca
acaaaggatatggttgcagccattttagaaacaacatataaagtacataaaacacaaggg
aattttaataatcatataggtttaccattaaccgttttaagtatgagtgaggatacagaa
atagcggttttagagatggggatgagtggtaaaggagaaattgaactattatctgaaatt
gcgcatccggatgttgcggtcattacaaatatcggtgaagcacatttaatggatttagga
tctagagaaggaattgcagaggctaagcttgagattacaaaaggcttaaaaaaagacgga
ttatttatttttcacggcgatgaaccacttttacaagagagagtgccaggactgtcttta
aaaacaactacttttggagaagcaagttctaatgattattaccctgcaaagattattcaa
gaaccaacaggaacattatttgaagtgaacaaagaggaatactttattcctgtacttgga
aaacataatgtgtggaatgctttagcagcctatgcagttgcggattattatggcgttgaa
aaggatgccataaaaaagggattttcgtccatgaagttaacagggatgcgtttagagtta
attcaagctaaaaatggagcatcaattattaatgatgcttataatgcaagtcctacttca
atgttagcagcaattgaccttattgagaatttaaaagactttgatcaaaagattgtcgtt
ttaggtgatatgcttgaattaggtgatgatgaagtagaatatcaccaacaagtaggaaga
gaaataaaacaaaataatatttcccacatcttcacttatggaaaacttgggaaagaaatt
gcaaaaggtgcaaaagaaaatcaatcggttgatacagttcatcattatgatcaaaaggat
gaattaattaagcatctacagtctatcgtgaaagaaaaggatattgttcttgtaaaagcc
tcaagaggaatgaagctggaagaagtcgtaaattcaattgtataa
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