Methylobacterium sp. NMS14P: LOK46_12700
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Entry
LOK46_12700 CDS
T10783
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mens Methylobacterium sp. NMS14P
Pathway
mens00300
Lysine biosynthesis
mens00550
Peptidoglycan biosynthesis
mens01100
Metabolic pathways
mens01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mens00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LOK46_12700
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LOK46_12700
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LOK46_12700
Enzymes [BR:
mens01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LOK46_12700
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WCS27645
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Position
complement(2668540..2669988)
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AA seq
482 aa
AA seq
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MTALWTREELESATGGRLTGAGRAIGGASIDTRTLQPGDLFFAIRGDTRDGHDFVPDALG
RGAGAAVVGAARAEALAAHGPVLAVPEEGADPVLTAMVRLGAAARARTRAQVVAVTGSVG
KTGTKEALRHVLSEQGETHASAASYNNHWGVPLTLTRMPRSARYGVFEIGMNHGAEIVPL
TAQVRPDIALITTIAPAHIEHFASLAAIADAKGEIFSGLQPGGVAILNRDAPHFDRLAAH
AQASRAGRVVTFGEHPDSDVRALKIVLRPDLSVIDAAVMGQPVTYKLGTAGRHAALNSLG
VMAVVHSLGADLARAALSLGGLTPPAGRGERTALEIGGGTAYLVDESYNANPVAVRAALA
TLAGIETGPRGRRIAVLGDMLELGAAAPDLHRGLAEAIEAARVDLVFTAGPLMRNLFEAL
PVSRRGAVADTAADLLEPLARTLRSGDAVMVKGSNGSRMGRIVEALKARYAVDPTRRTQA
VP
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcactctggacgcgggaggagctggaatccgctacgggcggccggttgaccggc
gccgggcgcgcgatcggcggcgcctcgatcgacacccgcacgctccagcccggcgacctg
ttcttcgcgatccgcggcgacacccgcgacggccacgacttcgtccccgacgccctgggg
cgcggggccggcgccgccgttgtgggcgccgcgcgcgccgaggcgctcgccgcccacggc
cccgtcctggcggtccccgaggagggcgccgacccggtcctgaccgcgatggtgcgcctc
ggcgccgccgcccgggcccggacgcgcgcgcaggtcgtggcggtcaccggctcggtcggc
aagaccgggaccaaggaggcgctgcgccacgtgctgtcggagcagggcgagacccacgcc
tcggcggcctcctacaacaaccactggggcgtgcccctgaccctgacgcggatgccgcgc
tcagcgcgctacggcgtgttcgagatcggcatgaaccacggcgccgagatcgtgccgctg
accgcccaggtccggccggacatcgcgctgatcaccacgatcgcgcccgcccatatcgag
catttcgcctcgctggccgcgatcgcggacgccaagggcgagatcttctccgggctccag
cccggcggcgtcgcgatcctgaaccgcgacgccccgcatttcgaccggctggccgcccac
gcccaggcctcccgggcgggccgggtggtgaccttcggcgagcatccggattccgacgtc
cgcgccctgaagatcgtgctgcggcccgacctgtcggtgatcgacgcggcggtgatgggc
cagcccgtcacctacaagctcggcacggccggccggcacgcggcgctgaactcgctgggc
gtcatggcggtggtccacagcctcggggccgacctcgcccgcgcggccctgtcgctcggc
gggctgacgccgccggcggggcgcggcgagcgcaccgccctcgagatcggcggcggcacc
gcctacctcgtcgacgagagctacaacgccaatcccgtcgccgtccgcgcggcgctggcg
accctcgcggggatcgagaccggaccgcgcggccgccggatcgcggtgctgggcgatatg
ctggagctcggcgccgccgcacccgacctgcatcgcggcctggcggaggcaatcgaggcg
gcccgggtcgacctcgtcttcacggccggtccgctgatgcgcaacctgttcgaggccctg
ccggtgagccgccgcggcgcggtggccgacaccgcggccgacctgctcgagccgctcgcc
cggaccctgcggtccggcgacgccgtcatggtgaagggatcgaacggcagccgcatgggc
cggattgtcgaggcgctgaaagcccgctacgcggtcgatccgacccggcggacccaggcc
gtcccgtga
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