Methanocaldococcus lauensis SG1: MLASG1_0127
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Entry
MLASG1_0127 CDS
T07808
Symbol
leuC
Name
(GenBank) Isopropylmalate/citramalate isomerase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mesa
Methanocaldococcus lauensis SG1
Pathway
mesa00290
Valine, leucine and isoleucine biosynthesis
mesa00660
C5-Branched dibasic acid metabolism
mesa01100
Metabolic pathways
mesa01110
Biosynthesis of secondary metabolites
mesa01210
2-Oxocarboxylic acid metabolism
mesa01230
Biosynthesis of amino acids
Module
mesa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mesa_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mesa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MLASG1_0127 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MLASG1_0127 (leuC)
Enzymes [BR:
mesa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MLASG1_0127 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MLASG1_0127 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAB3287327
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Position
I:117403..118680
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AA seq
425 aa
AA seq
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MGMTIVEKILAKASGKKEVSPGDIVMANIDVAMVHDITGPLTVNTLKEYGIEKVWNPEKI
VILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIREGVCHQVLPEKGHIVPGEVVVG
ADSHTCTHGAFGAFATGIGSTDMAHVFATGKLWFKVPETIYFNITGDLQPYVTSKDVILS
IIGEVGVDGATYKACQFGGETVKKMSIASRMTMTNMAIEMGGKTGIIEPDEKTIQYVKEA
MKKHGTERPFEIIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVKPAREVAGRPIDQVF
IGSCTNGRLEDLRMAIEIIDKHGGIADDVRVVVTPASREEYLKALKEGIIEKFLKYGCVV
TNPSCSACMGSLYGVLGPGEVCVSTSNRNFRGRQGSLDAEIYLASPITAAACAVKGELVD
PRDLE
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacaattgttgagaaaattttagcaaaagcttctggaaagaaagaggttagc
ccaggagatattgtaatggcaaacattgatgtggcaatggttcatgatattacaggacct
ttaacagtcaatacattaaaagagtatggaattgagaaagtttggaatccagaaaaaatt
gttatcttatttgaccaccaagttcctgctgatagtataaaagcagctgaaaaccatata
ttaatgagaaagtttgttaaagaacaaggtattaaatacttctatgatataagagaaggt
gtttgccaccaagtattgccagaaaaagggcatatagtccctggagaagttgttgttggt
gctgatagccatacatgcacacatggagcttttggagcttttgctactggtataggttca
actgacatggctcacgtgtttgctactggtaaattatggtttaaagttcctgaaacaatt
tactttaacattactggagatttacaaccttacgttacttcaaaggatgttattttatca
attataggagaagttggagttgatggagctacatataaggcatgtcaatttggaggagaa
actgtaaagaagatgagtattgcctcaagaatgactatgactaacatggctattgaaatg
ggaggtaaaactggaattattgagccagatgaaaaaacaatacaatatgtaaaagaggct
atgaaaaaacatggaactgaaagaccatttgaaattataaagggagatgaagatgcagaa
tttgccgaagtttatgaaattgaggctgacaagatagaaccagtatttgcctgcccacac
aatgtagataatgttaaaccagcaagagaagtcgctggaagaccaattgaccaagtattt
atcggctcatgtacaaacggaagattagaagacttaaggatggctattgaaattattgat
aaacatggaggaatagcagatgatgttagagttgtagttactcctgcatcaagagaagag
tatttaaaagctttaaaagagggaataattgagaaattcttaaagtatggttgtgtagtt
acaaatccatcttgctctgcatgtatgggttcattgtatggagttttagggccaggagag
gtttgtgtttcaacatcaaatagaaactttagaggaaggcaaggttccttagatgctgaa
atttatttagcatcaccaataactgctgcagcttgtgctgttaaaggagaattagtagat
ccaagggatttagaataa
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