Manihot esculenta (cassava): 110613911 Help Entry 110613911         CDS       T05761                                  Name (RefSeq) midasin isoform X3   KO K14572   midasin Organism mesc  Manihot esculenta (cassava) Pathway mesc03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:mesc00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     110613911  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:mesc03009]     110613911 Ribosome biogenesis [BR:mesc03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     110613911 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_3 AAA AAA_lid_5 AAA_7 AAA_16 AAA_22 AAA_18 AAA_6 Sigma54_activat nSTAND3 AAA_2 TsaE AAA_28 AAA_14 Sigma54_activ_2 ABC_tran AAA_30 bpMoxR RNA_helicase AAA_29 Dynein_heavy NACHT IstB_IS21 SRPRB ATPase_2 MDN1_4th DUF815 PduV-EutP SRP54 ResIII Motif Other DBs NCBI-GeneID:  110613911 NCBI-ProteinID:  XP_021611013 LinkDB All DBs Position 4:34082167..34124391 Genome browser AA seq 5471 aa AA seqDB search MAMDGSYSLESAVKRFLSRCPELARIQKLNDLVKKGHMVTEEEVINSVAELFVNPNYTIP LIGCLRPIARKIIDAAVSLLGQCNLSSNLDNTLVDSRELVKGEVAYFIDHFNNSGRGLTL HEFACLALCRAIDLDHSLLGSASAYFKFASPPFERIWRKKIVAEQFESVSDCLLASQVSY RLLLLECEFFSVRWDWSCFLELVKVTLNLDVGHGSQSEEISDIRWCGMQIMSIILKMSDK AIENFGVGAEEAASCLLRWEEFCQDVAMEKAGFYVESSENTMLDSSIIGRVAFSQQNFPS SLDHNSLVSLQFHKLEPVIKSRRLVNWNDESGSYPFVVTSTMKRSFDMVLLAVSQRWPVL LYGPAGAGKTALISKLAQDHGNQAVLSIHMDEQIDGKTLIGTYICGEQPGEFRWQSGSLI QAVVNGYWVVFEDIDKAPSDVQSILLPLLEGASFFVTGHGEEIRVAESFRLFSTISTSRI DVQCNAEGGNLLSTLWRRVMIGLPNCDDLQSIVKAWYPKLKPLAGKLIETFERVNYVSLH HIMGFQSGDLTLFGSLSRFSLRDLLKWCKRIVGLGFCPMGDVLTAYQCHCIYQEAVDIFA AFSPSSETRTKVMRDIAKLWTVPFPEAGILYPHKPEIQGSLAELRIGRVALQHAETLLHG QGRLVQMRSSLHVLERISCSVKYNEPVLLVGETGTGKTTLVQNLAKMVGQKLTVLNLSQQ SDVADLLGGFKPIDPQSICVLLYREFESLFSKTFSVKENDKLFAYLQKQIRKKNWVMLLN AFRKYVDNFQKKVRIERSGSGKKRKKPLDDEEMQRAWDNFSVKLETAHGQIGASSGMVFS FVEGAFVTALRNGDWILLDEVNLAPTETLQRINGVLEGDYGSLCLAERGDVTHIPRHPSF RIFACMNPATDAGKRDLPYSLRGRFTEYFVDDVLDKEDLKLFVNKFMEETRSNAELEQRV IDFYEIAKVNSEEKLQDGANQKPQYSLRSLYRALEYAREAKGKFGFQKAVYDGFQMFFVT MLDGPSAKIIKKMIEDKLLGGIKPSPVTFDAYLPVKKDCSSDDFLGNYVLTKSVKKQLEN LARAVFIRRYPVLLQGPTSSGKTSLVHYLAARTGHGFVRINNHEHTDLQEYLGSYISDAH GKLIFHEGILVKAVRNGYWIVLDELNLAPTDVLEALNRLLDDNRELFVPELRETVHAHPN FMLFATQNPPTFYGGRKMLSRAFRNRFVEVHVDEIPDYELNTIIEKRCKIPGSRAKIMVE VMKELQLHRQRSKVFAGKHGFITPRDLFRWANRLRTFGDSKEVMAEYGYYLLADRLRDEG EKLVVQEVLEKHLRVKIIKDNLYKDLVGVDSKSLGNIILTKSMRRLSFLLKRCYELREPV LLVGETGGGKTTVCQLLSTMLGSKLHILNCHQYSETSDFLGGFFPIRERSRLTSEFKYII ERLMQSKAYVHFPELLEISLDIGQAASTLDHLAAIITSYRHGQVSCPDVTAEDINTLEEM KLNLSQLHQKWKTIFVWQDGPLVQAMKAGDLFLVDEISLADDSVLERLNSVLEPERKLSL AEKGGPVMEEITAHPNFLVLATMNPGGDYGKKELSPALRNRFTEIWVSPVSDLDELRDIA SKRFSNPAFSYIVDAMINFWQWFNQLQVGRMLTVRDLLSWVEFINMTEGSLGPDYAFFHG LFLCLLDGLSLGTGISREDAALLREKCLSFLVKQLEVVDNTTLHKLSTMENYGWGDLGTT LDVSCTDDMLHDTVFGISPFYIGKGSENCETSGFEFLAPTTRRNALRVLRAMQIPKPVLL EGSPGVGKTSLIIALGKYSGHKVVRINLSEQSDLMDLLGSDLPVESDEGMKFAWSDGILL QALKEGCWVLLDELNLAPQSVLEGLNAILDHRAEVFIPELGLTFKCPSSFRVFACQNPFS QGGGRKGLPRSFLNRFTKVYIDELVEDDYLFISSSLYPSIPKPVLSKLIFFNKRLHEDTM IHHKFAQDGSPWEFNLRDVIRSCEIIQGAPDRLKFDCFVDIVYVQRMRTPADRKEVLQLF EDIFEFKPLINPYPRVQLNSNYLIVGNASVKRNSFYPSKLNSSQLTIVPSVRHSLEAALH CVQHQWLCILVGPPSSGKTSLIRLLAELTGNILNELNLSSATDISDLLGCFEQYDAYRNF RCICAQVERYVSEYCSILLEFSKTTFCERKDVITKWLAFLSCMGSSSLSTSNILENWKSV ATSLNLLVDIIEQLKLDVVNNGLPVSWSSNKLNKTVETILKLQEYLQRRQFSAKFEWVAG LLVKAIENGEWVLLENANLCNPTVLDRINSLVEPSGSITVNECGIVDGNPLVLRPHPNFR MFLTVNPTLGEVSRAMRNRGVEIFMMQPYWLLNEEKSAEFELKDVKRFLVLSGVPVGKLV ESMAKAHVYARNEGLRLNIQITYLELARWIKLFHQLLLNGSQPLWSLQISWEHTYLPSLG EAVGWDIINHGKFAFLSMAKLSESDFPVELSLHLPGGWPMPLKLRDYVFYSKEASVKQNC MYLGYLMSQYELGIKRDNVGLDQVFSTSHGGAYLIDLKRIHKFMFPMSLSWVFSSSYGNV EFDLKLTKKMLLFAADWTIEQATAIDYKLYRLWFNWLSSKLEHGHFFHCYENLLKQEFEH PIWKCIFHCHHELGSLHQVELNLWPVPLLSLDFVDLRPSNDMSNRLCKLLSNAINCVSLL RISFQQWNAQDVHGYGYEAQHFKMVLKPLQDLEKEILNMLVTSPAYDVLIKLYSKLLDDH MAFWHAFISSHFEQLLLSWHSLVKDVSKFRDFCPKAVENVLMMGSKHLDREFHLGSRQSL LWIHGGHPILPSSAKLYHKQQHLLDLCELTWPTHRNPYKQVDDELIELAASSDPELRSLA VQGICMSLYITSKSDEDNVKVTEQLEEMHQMLSERFRYEKQKLRAKLQLDEHAIFERNSA SCCVFVPEILGLKCGFTSWQEALPIIDSTSFFLDMELLQNLLTIVLVDPQGLQQALGGVS DLLESALKFSLTLSGRPPQNFIPHQKVLWTLEAWAPEDAVNAKVASYVLEMWFWWHLSLW NHYPVFLEDSSKMGGCDIPLPALLAKPVKTASVIHIVQDSCSIKDYFAHLWKLKVASKNI WESPPTGTNVLGILLSVARSLFQQIIYVHKREFDADKFSAINSIFCSFQKNMITQDKVQN LGVLIASSSDQSLNSLFYLFIEPLLRDLYIHCHSTDFHLNIGYAWLRVGGLRFSLLHSCQ DMDPAMKYSYKYSQLEERISSLELEIKVRQECEYLAGCFSSRKTDKKRVETLQMLEAEQK KLQRKMVFRSKPLKFNALRKECNEFLKLVIMVVDLASKIEVMELQQVLDQVCNWQETASC FVKRLSTEYKEYNDVAQPIQVAVYEMKLGLSLILSGALWKKNLDRTGVDSTEQVMESVCS FMKFPRGYILESISFNDIDSPVNFWEREINLLEKLVSISSDVNVERGVSVLQLKTALRLN ILVHVVHFVADAKKIDNASFKILDKMFNEFASMWMETKVQVKSKEGHDIQQYKFRPRAFE IRHLVDVDMSTFGKLANDNFSEWLELLSEDECLEKVETVTQYENLEEEWNLMQESLLNNM IQLHNKLFGSANLVLNPGTFSISEADRLLLFANSYSLGAGITKGLGGLVSSCLDAKLMPE HLLRLCFEHERIFVSSHKSSTNYNFYKDSNASEMAKMVKSLATLQKRILSLLNEWEDHPG LQKIIDTVEALLNIPSGTPLAKALLGLRFLLNRAKVLEENGSKFSLSDQLAPIIALVCSW QKMEFDTWPALLDEVQDQHEINAAKLWFPLFSVLHHSHAADVSAHEQSTIESLEEFINTS SMGEFKKRLQLLFAFLGQVTAGRCLGIETYSSPWQEKNLYILYNVFGYYVQLLPRILEHI EINRRNIDMELKELLKLCRWERPEACLSAENSKRTRQKLRKLIQKYTDVLQQPAMLFLNQ DAVRKGLKIQSLEGPTPLDDISETNVKLLSAVLNQFSDKHRLLWYCGWREKVNDTLQKLH VDKTSKSCFPGEDGLSVCNFYDITSIMQQYLTSKSACISQLEQWNLLCERLEKISRTTIN CDNLWKDTEKNIGKKRAFSELLKLLESSGLHKHKFEIMKVSNSLNWLFIQPSYEMQHLLL TQNRLSYGASTASALQCQPDEGVDTEWKEVNEFYFKSTASVQLLQRICLKPHEDITYEQA SRSVSFLNHLIVIQQSQRAATYNFSKNLKHLRECASTLENLYSRCSVSNNRSGSECSISS NQYAVFQCLWKQKRIFDGLVALLVEEAVLFRAAKSTHFKSCESIKPAINHVLQFIEKFTP LMQKTKESLDDYLVGRLGVVQTLVQESLDKCLLHRVGDTSIGPIRPFTISKKMEQLVWKN FQVIKDFEEHLIEFRRQNLNRSSVMETLLGRFDDVLEKGKLLAEELDFSLKAKSRNDSTC TLDKSICHESCSDLDALFGGSLRKTFQIIVNVLTKQCSTSNGYAPSKGSSENITSWEYLF KSSIEDLNLEELYDNLLKIIICAEKMMNSSGCETSPSFPVGACFQHLHAFSAVILTFGDS LLQDLLAMHKMVSVMTHALADVLASLFSKGFGSAAKDEEDDSNHSKSQDATGTGMGEGLG LNDVSEQITDEDQLLGTSEKPSEAQDASGEAPNKNDKGIEMEQDFTADAFSVSEDSEEGN DEGEDDEQLESAMGETGADNEVIDEKLWDKEEDENLNNANEKYESGSSVRDRDASSRELR AKEDYAADDDDEKPGEVNSEEIDKLTDEVGNQEDLDDKVDSMDDVHMDKYESLADPTGID LDDLKERSEEDMDVDEEMNGEEPDFNEEISPEGESAENENHDQSAENGGGKENEDPVDDE TKAEVETEPVERNDPGGDDEENTDMNSNSSRQHLFEQGIYDKFNDHVPNTASASQPNGDS QVSDSRNVVQETKMSDTREAYNDIAPPKSVPSGPTSEMDMMVYDSSSNGGLTDDQQKSEL PQSESLSFQENKPNPYRNVGDALDEWKQRVKVSVDLEVDNKEAPGELEDKNADEYGYVPE FEKGTAQTLGPATSDQVDTNIDSIKTDEDKPAAASDDAAKMDIDEHNSEEGHLKHYGSVL KNNTEEQMQISNSEKPYNGGSPEIYGHNDVPESFTESLVSVRKSYLNEDMHCLSKLSIDD NELGKAQDLGEITLDGRSNATVLWRRYELLTTRLSQELAEQLRLVLEPTLASKLQGDYKT GKRINMKKVIPYVASHYRKDKIWLRRTRPNKRDYQVVIAVDDSRSMSESCCGDFAIESLV TVCRSMSQLEMGNLAVASFGKKGNIKLLHDFDQPFNGEAGVKIISSLTFRQENTIADEPV VDLLKYLTNMLDTAVAKARLPSGQNPLQQLVLIIADGRFHEKEKLKRCVRDFLSKKRMVA FLLLDSPQESIMDQMEASFVGEGEKRVLKFTKYLDSFPFPYYIVLKNIEALPRTLADLLR QWFELMQYSRD NT seq 16416 nt NT seq  +upstreamnt  +downstreamnt atggcaatggatggaagttacagtctcgaatctgcagtcaagaggttcctttcacggtgc ccagagcttgctagaattcaaaagctcaatgatcttgtaaagaaggggcacatggtgaca gaagaagaagttataaattcagtagcagaactatttgtcaatccaaattatacaatccct ttgattgggtgtctcagaccaatagctcgaaagatcatagatgcagctgtgtcgttgtta ggtcaatgcaatctgagctccaacctggataacactctggtggattcaagagagcttgtt aagggagaagttgcttattttatcgaccatttcaataacagtgggaggggtttgactctt cacgagtttgcttgtctagctttatgccgtgccattgatttggatcactcgttattgggg tctgcatctgcctacttcaaatttgcatcacctccttttgaacgcatttggaggaagaaa atagttgctgagcagtttgagtcagtaagtgattgcttacttgcctcacaagtatcctac cgcctcctcctactggaatgcgagtttttctctgtaagatgggattggtcctgttttctt gagctcgtgaaggtaactctaaatcttgatgtgggccatggttctcaaagtgaggagata tcagacataagatggtgtgggatgcaaataatgtcaatcattttgaagatgagtgacaaa gcaattgaaaattttggtgttggagctgaagaagcagcatcatgtttattgcggtgggaa gagttctgtcaagatgtagctatggagaaggctggcttttatgttgaatcatctgaaaac acaatgttggattcttccatcattggcagagttgctttcagccaacaaaactttccgagt tctttggaccacaattcactggtttcattgcagtttcataaacttgagccagtaattaag agtagaagattggttaactggaatgatgaatctggaagctatccatttgtagtgacatct acgatgaagagaagttttgacatggtactcttagcagtgagtcaaaggtggcctgtcctt ctatatggccctgcaggtgctgggaaaactgctctcattagcaagttggctcaggatcat gggaaccaagcagttctctctattcacatggatgaacaaatagatgggaaaacattgatt ggcacttatatatgtggtgagcaacctggtgaatttaggtggcaatccggatcacttatc caggctgttgtaaatggatattgggttgtatttgaagacattgacaaggcaccatcagat gttcaatcaatcttattacctttactggaaggtgcaagcttctttgtaacaggtcatggg gaggaaataagagtagcagaaagctttcggctgttctccaccatttctacttcaaggatt gatgtgcagtgcaatgcagaaggtggaaatttacttagcaccctttggaggagagtgatg attgggctgccaaattgtgatgacttgcaaagtatagtgaaggcatggtatccaaaattg aagcctcttgctgggaaacttatagaaacatttgaaagagttaactatgtgtctctacac catattatgggatttcagtctggagatttgactctctttggatcactgagcaggttctca ttaagggatctccttaaatggtgcaagcggatagtaggcttgggcttttgccccatgggg gatgtgttgacagcttatcagtgtcactgtatttatcaggaggctgtagacatatttgca gcattttctccatcaagtgagactcgcacgaaagttatgagagacattgcaaagttgtgg acagttccattccctgaggcgggaattctatatcctcataaacctgaaattcagggttct cttgcagaactaaggattggacgagttgctcttcaacatgcagaaactttgttgcatggc caagggaggcttgttcagatgcgtagttctctgcatgtgcttgagagaatttcttgctct gttaagtataatgagcctgttctcttggttggtgaaactggaactgggaaaactacactt gtacagaatctggcgaaaatggttggtcagaagcttactgttctgaatttgagtcaacaa agtgatgttgctgatttattaggaggatttaagcccatagatcctcaatctatctgtgtt ctcctttatagggagtttgagagtctcttttctaaaactttctctgtgaaggaaaatgat aaactttttgcctacttacaaaagcagataagaaagaagaactgggtgatgctattgaat gcatttaggaagtatgtggataatttccaaaagaaagtacgaatagaaagatctggatct ggaaagaagcgaaaaaaacctttggatgatgaagaaatgcagagagcttgggataatttc tctgtgaaacttgaaactgcccatgggcaaattggggcttcatctggaatggtcttttca tttgtagagggagcatttgtaactgcacttagaaatggcgattggattttgctggatgag gtgaatttagctcctactgagaccttgcagagaatcaatggtgtacttgaaggagactat gggtcactctgtttagctgaaagaggggatgtcactcatatacctagacatcctagtttt cgtatatttgcctgcatgaatccagcaactgatgctggaaaaagagatttaccatattct ttgcggggccggtttacagagtactttgttgatgatgtgttggataaagaagatctgaaa ttatttgttaacaagtttatggaggagacccgatcaaatgcagaactagaacaaagagta attgatttctatgaaatagccaaagtgaactctgaagaaaagctgcaagatggggctaat cagaagcctcaatacagtttaagatctttataccgtgcactagagtatgccagggaggct aaaggaaaatttggatttcaaaaggcagtttatgatggcttccaaatgttttttgttacc atgttggatggacccagtgccaagattataaaaaagatgattgaggataagttattaggc ggtattaaaccttcaccagtaacttttgatgcatacttaccagttaaaaaagactgcagt tctgatgatttcttggggaattatgtcttgacaaagagtgtaaagaagcaacttgagaat ttagctcgtgctgtttttattaggagatatcctgttttgttacaggggcctacttctagt ggaaaaactagccttgttcattatcttgctgcaagaactggtcatggatttgtgcggata aacaaccatgaacacactgatctgcaggaatatttaggttcttacatatcagatgctcat ggaaagctcatttttcacgaaggtatattggtcaaggctgttcgcaatggttattggatt gttttggatgagctaaatcttgcccccactgatgtgctggaagcattgaatcgtttgtta gatgataatagagaactttttgtgccagaattgcgcgagactgtacatgcacatcctaat tttatgctttttgctactcaaaatccacctactttctatggtgggcgtaaaatgctttct cgagcatttcgcaatcgttttgtggaggttcatgtagatgaaattccagattatgagttg aacacgataatagaaaaaaggtgtaaaatccctggaagccgtgcaaagattatggttgaa gtcatgaaggagttgcagttgcacaggcagaggagcaaagtatttgctgggaagcatgga ttcataactcctagagatttgtttcgttgggctaatcgtttgagaacatttggagattct aaggaagtaatggcagaatatggatactatcttctggcggataggctccgagatgaggga gagaaacttgtggttcaagaagttttggaaaagcatctccgagtgaaaattataaaagat aacttatataaggatttggttggcgtggactctaagagtcttgggaacatcatcttgacc aaaagtatgaggagattgtcctttcttctcaagcgttgctatgagttacgtgagcctgta ttacttgttggtgaaactggtggtgggaagaccactgtctgtcagttattgagtactatg ttgggttcaaaattgcacattttgaattgtcaccaatactcagaaacatctgatttcctt gggggattttttcctatccgggaaagatcaagactgacatcagaattcaaatatataata gaaagactgatgcagtcaaaggcttatgtccacttcccggagctcttggaaatttctcta gatattggtcaggccgcttccactctggatcatcttgctgcaataataactagttataga catggtcaggtttcatgtccagatgtcactgcagaagatatcaatactctcgaggagatg aagttgaaccttagtcagctgcatcagaagtggaagacaatatttgtgtggcaagatggg cctcttgtgcaagccatgaaagctggtgatctatttcttgttgatgaaatttccttggct gatgatagtgtgctagaaagattgaacagtgttctggagcctgaaagaaaactgtctttg gcagagaagggaggtcctgttatggaagagataacagcccacccaaactttttagtgctt gcaactatgaatcctggaggtgattatggtaagaaggaattgtctccagctcttcgtaac cggtttactgagatctgggtttctcctgttagtgatctggatgaacttagagatattgct tctaagaggttttccaatccggcattctcatacattgtggatgctatgattaatttctgg cagtggttcaaccagttacaagtagggagaatgcttactgtgagagatctcctatcttgg gttgagtttattaacatgactgaaggaagtttaggacctgattatgcgttcttccatggg ctttttctttgtttgcttgatggcttaagtctagggactggtatttccagagaggatgct gcactattaagggagaaatgcctgtcttttcttgtaaagcaacttgaggtggtagacaat actacacttcataaactttcaactatggaaaattatggttggggtgatcttggaacaacc cttgatgtttcttgcactgatgacatgcttcatgacaccgtcttcggtatcagtccattt tatataggaaaaggttctgaaaactgtgagactagtggttttgaatttttggcaccaact acacgacgaaatgctttacgtgttttgcgcgctatgcaaatcccaaagccagtactattg gaaggcagtcctggtgttggtaaaacaagtttaattattgccttgggaaagtattcaggt cataaggttgtacgaataaacttatctgagcagtctgacctaatggatttgctagggtca gatttacctgttgagagtgatgagggaatgaaatttgcatggtctgatggaatcttgctg caggctttgaaggagggttgttgggttttgctggatgaacttaatcttgctccacaatct gtcttagagggtttgaatgctattctggatcaccgtgcggaggtcttcattccagagctt ggccttacttttaaatgtccatcatctttcagagtctttgcatgtcaaaatcctttttct caaggtggtggcagaaaaggccttccaagatcttttttaaaccgtttcactaaggtgtac atagatgagctagttgaggatgattatttattcatctctagctccctgtacccctcaatc ccaaagcctgtgctttcaaagctcatttttttcaataaaagattacatgaggataccatg atacatcacaagtttgcacaggatggctccccgtgggagtttaatttgcgtgatgtgatt cgctcatgcgagatcattcaaggtgccccagataggttaaaatttgattgctttgttgat attgtttatgttcaaagaatgcgtactcctgctgatcgcaaggaagttttacagctgttt gaagacatctttgagttcaagccattgataaatccttaccctcgagtacagcttaattct aactacttaattgtgggaaatgcttctgttaaaagaaacagtttctacccatctaagctg aatagtagtcagttaactattgtgcctagtgttcgccatagcttggaagctgcattgcat tgtgtacagcatcagtggttgtgcatcttggttggtccaccatcatctgggaagacttca ttgataaggttgttagctgagctcaccggaaatatactaaatgagctaaacctttcatct gcaactgatatatctgatttacttggatgttttgagcaatatgatgcttaccgcaacttt cgttgcatttgtgctcaagttgagcgctatgtttctgagtattgcagcatattgttggaa ttttcaaagactacattctgtgaaagaaaggatgtaatcaccaaatggcttgctttctta tcttgcatgggttctagttccttgtcaacttccaacattttagagaactggaagagtgtt gccacttctctgaatttattagttgatattattgagcaattaaagttggatgtggtaaac aatggcttacctgtttcttggtcgagcaataaactgaataaaactgttgagacaattttg aagttgcaagaatatctgcaaagaaggcagttttcggcaaagtttgaatgggttgccgga ttacttgtgaaggcgatagaaaatggtgaatgggttcttctggagaatgcaaacctttgt aatcccacggttcttgatagaatcaattctttggtggagccgagtggatcaattacagtt aatgaatgtgggattgttgatggaaacccactggttcttcgtccacaccccaattttcgg atgttcctcacagttaatccaactttaggtgaagtatctcgagcaatgcgaaatagagga gttgaaatatttatgatgcagccatattggctgctgaatgaggaaaaaagtgcagaattt gaattaaaggacgtgaaaagatttcttgttttatctggtgttcctgttggtaaattagtt gagtcaatggccaaagcacatgtctatgctaggaatgaagggctacgccttaatattcaa attacatatcttgaacttgcacgctggattaagttattccaccagcttcttctaaatgga agtcagcctctctggagtcttcaaattagttgggagcatacttacctgccttccttaggt gaggctgtgggatgggatattattaatcatggcaagtttgctttcttatcaatggcaaaa ctttcggaatctgattttccagttgaattatctttgcatttgcctggtggatggccaatg ccattgaagttaagggattatgttttttactcaaaggaagcttctgtcaaacagaactgc atgtatttgggataccttatgtctcaatatgaattgggcataaaacgggataacgtaggt ttggaccaagttttttctactagccatggaggggcttatttgattgatttgaagaggata cataaattcatgtttcctatgtctttaagttgggtgttttccagctcatatgggaatgta gagtttgacctaaagttgactaagaagatgctactgtttgctgccgattggaccattgaa caggctactgcgattgattataagctatatcgtctttggtttaactggcttagctctaaa ctggaacatggtcatttttttcattgttatgaaaatttgctgaagcaggaatttgagcat cctatttggaagtgtatttttcactgccaccatgagcttggatctcttcaccaagtagaa ttgaacttgtggccagtaccattgctttcactggactttgttgatttaagaccatcaaat gacatgtcaaatagattgtgcaaacttctatctaatgccattaactgtgttagtcttcta agaatttcttttcaacagtggaatgctcaggatgtgcatggctatggctatgaagctcag catttcaaaatggtattgaagcctttgcaagatttagagaaggaaatccttaatatgctg gttacatctcctgcatatgatgtgctcattaaattatattcaaagcttcttgatgatcac atggcgttttggcatgcttttatctcatcccacttcgagcaactgctgttgtcttggcat tctttagtgaaggatgtttcaaaatttcgtgatttctgtccaaaagctgtggaaaatgtc ttaatgatgggaagtaagcacctagatagagaatttcatctgggatcacggcagtctttg ctatggattcatggtggtcacccaatattaccttcctctgctaaactgtatcataagcag caacaccttttggacctatgtgagctaacctggccgacacatagaaatccatataagcaa gtggatgatgaactcattgagttagctgcatcttctgatcctgaacttcgttctcttgca gtgcaaggtatttgcatgtcattgtatattaccagtaaatctgatgaggataatgttaag gttactgagcagttggaggagatgcatcagatgctatcggaaagatttagatatgagaag cagaaattgagagcaaaactacagttggatgagcatgctatttttgagagaaattcagct tcttgttgtgtttttgtccctgaaatattgggcttgaagtgtggctttaccagttggcaa gaggctcttcctataattgacagcactagttttttcctagacatggagttgcttcaaaac cttttgacaattgttttggttgatccccaaggtttacagcaggcgcttggtggtgtgtct gacttgctggaatctgccttaaaattctcgttgactttatcaggaagacctccgcaaaat tttataccacatcaaaaagttttatggacacttgaagcatgggcacctgaagatgcagtg aatgcgaaagttgcaagttatgttcttgagatgtggttttggtggcatttgtctttgtgg aaccattaccctgtttttcttgaggactcttcaaagatgggtggttgtgatattcctctt cctgctctgcttgctaagccagtgaaaacagcatctgtgatccatattgtgcaagattca tgttctattaaggattattttgcacatttgtggaaacttaaagttgcttcaaaaaatatt tgggaaagtcctccaacaggcacaaacgttctcggtattttgttatcagttgctcgctct ctcttccaacagattatatatgtgcataaaagagaatttgatgctgataaattttctgca atcaattccatcttctgctccttccaaaagaacatgataacgcaagataaggtgcaaaat ttgggtgtgctcattgcatcttcaagtgatcaaagtttgaattccttgttttatctgttt attgagccactgcttagagatctttatattcattgccattccactgacttccatttgaac attggttatgcctggttacgggttgggggactacgctttagtctcttgcatagttgtcag gatatggatcctgccatgaaatactcttacaagtactcacagctagaggagaggatatcg tcacttgagcttgaaattaaggttcggcaagaatgtgaatatctagcaggatgtttttct tctagaaagactgataaaaagagagttgaaacattgcagatgctggaagctgagcaaaaa aagctccaaagaaagatggtatttcgcagcaagccattaaaatttaatgcactgagaaaa gaatgcaatgagttccttaaacttgttataatggtggtcgatttggcgagtaaaattgaa gtcatggagttgcaacaggttcttgaccaagtctgtaattggcaggaaacagcctcttgt tttgttaaacgattgtcaactgaatataaggaatacaatgatgtagcccaaccaattcaa gttgcggtatatgagatgaaactgggcctgtcgcttattctttctggtgccttgtggaaa aagaatttagatagaactggggtggatagtacagagcaggtcatggaatcagtttgctca ttcatgaaattcccaagaggatatatacttgaatcaatttctttcaatgatattgacagt cctgtaaacttctgggaacgggaaataaatttgctggaaaagctggtttccatttcaagt gatgtcaatgttgaaagaggggtgtctgtcttgcaactcaaaactgctcttcgtttgaat attcttgtccatgttgtccactttgtggctgatgcaaaaaagatagataatgcttctttc aagatactagataagatgttcaatgaatttgcaagcatgtggatggaaacgaaagttcag gtgaaaagcaaagaaggccatgatattcagcaatacaaattcaggcctcgtgcctttgag atcagacatcttgttgatgttgatatgtcaacttttggcaagttagcgaatgacaatttc tcagaatggctagagttgctttctgaagatgaatgtttggaaaaggtggaaactgttacg cagtatgagaacttggaggaggaatggaacctcatgcaggaaagtttactgaacaacatg atccagttgcacaacaaactatttggctccgctaatcttgtcttaaatcctggaactttc tctatatctgaggcagataggttgcttttgttcgccaactcttattcattgggtgcaggg ataactaaaggtctgggaggcctagtttcttcttgtttagatgcaaaactgatgccagag catttacttcgcctttgttttgagcatgagcgtatatttgtttcatctcataaatcatct accaattacaacttttacaaggattcaaatgcttctgagatggctaagatggtaaaatca cttgccactcttcaaaaacgaattctgagccttctgaatgagtgggaagatcaccctggt ctccagaaaatcatagatacagtagaagcgctcttgaatattccttctggcactcctctg gcgaaggctcttttaggattgcgcttcctacttaacagagccaaagtgttagaagaaaat gggtccaaattctctctgtctgatcaattagcacctattattgctctagtttgctcatgg caaaagatggaatttgacacttggccagcattgcttgatgaggtccaggatcagcatgag attaatgcggccaagttgtggtttcctctattctcagttttgcaccatagtcatgcagct gatgtttctgcacatgagcaatctacaatagagagtttggaagagttcattaacacttca agcatgggtgaatttaaaaaacgtcttcagcttctttttgctttccttggtcaagtcact gctggtagatgccttggaattgaaacctattcaagtccttggcaggagaaaaatttgtat atcttgtacaatgtgtttggatactatgttcaacttttgccaagaatcttggagcacatt gaaattaatagaaggaatattgatatggaactgaaagaactcctgaagctatgccgatgg gaacgacctgaggcttgcctatctgctgaaaactcaaaaaggacccggcagaagctcagg aagctaattcaaaaatacaccgatgtgcttcaacaaccagcaatgctttttcttaatcag gatgctgtaaggaaaggattaaaaattcaatctctggaaggtcctacgcccctcgatgat atctcggagacaaatgtcaagttgttgagtgctgttctgaatcagttcagtgacaaacac aggctcttgtggtattgtggttggagggaaaaagtaaatgatactttgcagaagttacat gttgacaagacttctaaatcatgctttcctggtgaagatggtttatcagtttgcaacttt tatgatattacaagtattatgcagcaatatttaacttctaagtctgcatgcatatcacaa ctggaacagtggaatctgctgtgtgagagacttgaaaaaataagtagaactacaatcaat tgtgataatctctggaaagatactgaaaaaaatatagggaagaagagggccttttctgaa cttctaaagctgctggagagcagtgggttgcataagcacaagtttgaaattatgaaggta tccaacagtttgaactggctgtttattcagccatcgtacgagatgcagcatttgctactg acgcagaacagactgtcttatggagcttctactgccagtgcattgcaatgtcagcctgat gaaggtgtggatactgaatggaaagaagttaatgaattttactttaaaagcacggcatcc gtgcagcttctgcaaaggatttgtctgaaaccccatgaagatattacttatgagcaggct agtaggtctgtctcgtttctgaaccatctcatagttatacaacagagccaacgtgctgct acctacaatttttctaagaatttgaagcacttgcgggaatgtgcatctaccttggaaaat ttgtactctaggtgttctgttagtaacaatagatctggaagtgagtgctctatttcgtca aaccaatatgcagtctttcaatgtttatggaaacagaagcgaatttttgatggtctagtt gctctgctagttgaggaagcagtattgttcagagcagcgaaaagtacccattttaaatca tgtgaaagtatcaagcctgcaataaatcatgttcttcaattcattgaaaaatttactcct ctcatgcagaaaaccaaggaatcactggatgactatcttgttggccgtcttggagttgtg caaactcttgtacaggaatctttagataaatgtcttcttcatcgtgttggcgatacatct attggtcccatacgtccattcaccatttcaaagaaaatggaacaattagtatggaaaaac tttcaagttattaaggactttgaggagcatcttattgagttccgcaggcaaaatttgaat agaagctcagtaatggagaccctgcttggtcgttttgatgatgtattggaaaagggcaag ttgctggctgaagagcttgacttttctttaaaggcaaaatcaagaaatgactcaacatgc acattggataaatccatctgccatgaaagttgttctgatctagatgctttatttggtgga tccctaagaaaaacatttcaaattatcgttaatgtgctgacaaagcagtgttcaacaagt aatggatatgctccgtccaaagggtcatcagagaacatcacctcatgggaatatctgttc aaatcatcaatagaagatttgaatttggaggagttatatgacaatcttctcaaaataata atttgtgcagaaaaaatgatgaattcttctggctgtgaaacttccccttctttccctgtt ggagcttgttttcagcatctacatgcattttcagctgtaatattgactttcggtgatagt ttacttcaagatcttctagccatgcataaaatggtttctgtaatgactcatgctcttgcg gatgttttagcttcattgttctccaaaggttttggcagtgctgccaaagatgaggaagat gactccaatcatagtaagtctcaagatgcaactggaactggcatgggtgaaggtttgggg cttaatgatgtcagtgaacagataactgatgaagatcaactactcggcacttctgaaaag ccaagtgaagcacaagatgcctctggcgaagctcccaataagaatgacaagggaattgag atggagcaggatttcactgctgacgcattcagtgtaagtgaggactctgaggaggggaat gatgaaggtgaggatgatgagcaactggagtctgcaatgggggaaacaggagctgacaat gaagtgattgatgagaaactttgggataaggaggaagatgaaaaccttaataatgcaaat gagaagtatgaatctgggtcatcagttagggacagggatgcaagcagtagggagcttaga gcgaaggaggattatgctgctgatgatgatgatgaaaaacctggagaggttaattccgag gagatcgataaactcactgatgaggttggaaaccaagaagatcttgatgataaagtagac agcatggatgacgtacatatggataagtatgaatcacttgctgatccaactggaatagat cttgatgacttgaaagaaaggtctgaagaggatatggatgtggatgaagagatgaatgga gaagagcctgatttcaatgaagagataagtccagaaggcgagtctgctgagaatgagaac catgatcagtccgctgagaatgggggtggcaaagaaaatgaagatcctgttgatgatgaa actaaggcggaggtggaaactgaacctgttgaaagaaatgatcctggtggggatgatgaa gagaacactgacatgaattcaaactcatcaaggcaacatttgtttgaacagggaatttat gataaattcaatgatcatgttcctaatacagcatctgcatcacaaccaaatggtgactcg caggtatcagattcaagaaatgttgtacaagaaacaaaaatgtctgataccagagaggct tataatgacattgctcccccaaaaagtgtaccttctggtcctacctctgagatggacatg atggtctatgactcatcaagtaatggaggattaactgatgatcaacaaaaatcagaactc cctcagtcggaatctttatcttttcaggaaaacaaaccaaacccttataggaatgttggg gatgcacttgatgagtggaagcaaagggtcaaagtgtctgttgatcttgaggtagacaac aaagaggcgcctggtgagttagaggacaagaatgctgatgaatatggatatgttcctgag tttgaaaagggaacagctcagacattaggccctgctacttctgatcaggttgacacaaat attgatagtattaagacagatgaggataagcctgcagcagcaagtgatgatgctgccaaa atggacatcgatgagcacaattctgaagaagggcatctcaaacattatggctcagtcctc aaaaacaatacagaagagcagatgcagatctctaattctgagaagccatataatggggga tccccagaaatttatggacataatgatgttccagaatcctttacagagagtttagtctct gtcagaaagtcttacttgaatgaggacatgcattgtcttagcaaactttctatagatgac aatgagctgggaaaagcccaggatctgggagaaataacccttgatggcagaagtaatgcc actgttctttggagaagatacgagttgcttacaacaaggttgtcacaggagttggctgaa caattacgcctagttttggaacccactcttgcaagcaagcttcaaggggattataagact ggaaagcgaatcaacatgaagaaggtaatcccttatgtagcaagtcactaccggaaagat aaaatatggctcagaagaacccgtccaaacaaacgagactaccaagttgttattgctgtg gatgactcccgaagtatgtctgagagttgttgtggagattttgccattgaatctttggtg acagtgtgtcgttccatgtctcaactggaaatgggaaatttggctgttgcaagctttgga aagaagggaaatataaagttactgcatgattttgatcagccatttaatggggaggctggg gtaaagataatctccagtttgacattcaggcaggagaataccattgccgatgaaccagtt gttgatctgttgaagtatctgacaaacatgcttgatactgcagttgcaaaagcacgactc ccttctggacaaaacccactacaacagcttgttttgattattgcggatggacggttccat gaaaaggagaagttgaagcgctgtgtcagggatttcttgagtaagaagcgaatggttgct tttctgcttctggatagtccgcaagagtcaattatggatcaaatggaagcatcatttgtg ggtgaaggtgaaaaaagagtacttaagttcactaaatatctagactcttttcccttccca tattatattgtattgaagaacattgaggcacttccaaggacccttgctgatttattgaga cagtggtttgagcttatgcagtattctagagattga

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