Methanocaldococcus lauensis SG7: MLAUSG7_0427
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Entry
MLAUSG7_0427 CDS
T07631
Symbol
leuB
Name
(GenBank) 3-isopropylmalate/3-methylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mesg
Methanocaldococcus lauensis SG7
Pathway
mesg00290
Valine, leucine and isoleucine biosynthesis
mesg00660
C5-Branched dibasic acid metabolism
mesg01100
Metabolic pathways
mesg01110
Biosynthesis of secondary metabolites
mesg01210
2-Oxocarboxylic acid metabolism
mesg01230
Biosynthesis of amino acids
Module
mesg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mesg_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mesg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MLAUSG7_0427 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MLAUSG7_0427 (leuB)
Enzymes [BR:
mesg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
MLAUSG7_0427 (leuB)
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Motif
Pfam:
Iso_dh
DUF6421
Motif
Other DBs
NCBI-ProteinID:
CAB3287860
UniProt:
A0A8D6PST8
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All DBs
Position
I:367638..368639
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AA seq
333 aa
AA seq
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MHKICVIEGDGIGKEVIPATIKVLEATGLPFEFVYAEAGDEVYKRTGKALPEETIETALD
CDAVLFGAAGETAADVIVKLRHILDTYANVRPVKAYKGVKCLRPDIDYVIVRENTEGLYK
GIEAEIDEGITTATRVITEKACERIFRFAFNLARERKKMGKEGKVTCAHKANVLKITDGL
FKRVFYKVSEEYKDIKAEDCYIDAMNMYIITKPQTFDVVVTSNLFGDILSDGAAGTVGGL
GLAPSANIGDEHGLFEPVHGSAPDIAGKKIANPTATILSAVLMLRYLGEYEAADRIERAL
EEVLALGLTTPDLGGDLNTFEMAEEVAKRVRGE
NT seq
1002 nt
NT seq
+upstream
nt +downstream
nt
atgcataaaatatgcgttatagaaggagacggaataggtaaggaggtaattcctgctaca
ataaaggttttagaagctacagggttaccatttgagtttgtttatgcagaagcaggagat
gaagtttataaaagaactggaaaagcattaccagaagaaactattgaaactgccttagat
tgtgatgctgttttatttggggctgctggagagactgcggcagatgttattgtgaaatta
aggcatatcttagatacatatgccaatgtaagaccagtaaaagcatacaaaggagttaaa
tgcttaagaccagatattgactatgttattgttagagaaaatactgaagggctttataag
ggaattgaggcagagattgatgaaggaataacaacagccacaagagttataactgaaaag
gcatgtgagagaatatttagatttgcctttaatttagcaagggaaaggaaaaaaatgggt
aaagaaggaaaagtaacctgtgcccataaagcaaatgttttaaaaataactgatggttta
tttaagagagtattttacaaagtatctgaggaatataaagatataaaagcagaagactgc
tatatagatgctatgaacatgtatataattactaaaccacaaacatttgatgtagtagta
acatccaatttatttggggatattctctcagatggagcggctggaactgttggaggttta
ggtttagccccttctgcaaatattggagatgaacacggattatttgagccagttcatggt
tcagccccagatatagctggaaagaaaatagcaaatcctactgctacaatattaagtgct
gtgttaatgcttagatacttaggagagtatgaagcggctgataggatagagagagcatta
gaagaagttttagcattaggtttaacaactcctgacttgggaggagatttaaacactttt
gaaatggcagaggaagttgctaagagagttagaggagaataa
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