Methylobacterium sp. 4-46: M446_0005
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Entry
M446_0005 CDS
T00679
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
met
Methylobacterium sp. 4-46
Pathway
met00230
Purine metabolism
met01100
Metabolic pathways
met01110
Biosynthesis of secondary metabolites
Module
met_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
met00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M446_0005
Enzymes [BR:
met01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
M446_0005
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACA14593
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Position
6842..9055
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AA seq
737 aa
AA seq
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MIRNDIAITPDLVRQHGLTDEEYARFKELIGREPTITELGIVSAMWNEHCSYKSSRIHLR
TLPTKAPWVIQGPGENAGVIDIGDGRACVFKMESHNHPSFIEPYQGAATGVGGILRDVFT
MGARPIAALNALRFGSPDHPRTRHLVSGVVAGIGGYGNSFGVPTVGGSVGFHRRYDGNIL
VNAMAVGLARADAIFYAAATGVGNPIVYLGSKTGRDGIHGATMASAAFDESSEEKRPTVQ
VGDPFAEKLLLEACLELMASGAVIAIQDMGAAGLTCSAVEMGAKGNLGVELDLDAVPTRE
AGMTAYEMMLSESQERMLMVLKPGMEEEAKAIFVKWGLDFAIIGHTTDTLRFVIKHGGET
VADLPIKELGDEAPLYDRPHRTNMHHPVLRAEDVPAPVTHGEALRRLMGSPDLASKRWVW
EQYDHYILGNTVQKPGGDAAVVRVEDGPKGLALTTDVTPRYCEADPVEGGRQAVAEAYRN
ISAVGGRPLAVTDNLNFGNPEKPEVMGQFVGCIQGIGEACRALDFPVVSGNVSLYNETNG
VGILPTPTIGGVGVVDDVRRIATLALKREGDALVLIGRSQGWLGQSLYLAEICGREEGAP
PPVDLAAERRNGEFVRGLIASGLVDTVHDLSDGGLAVALAEMAMAGRIGAALPECPLPIP
AHAYLFGEDQGRYLLAVEPETVPDLLYSAAAQGIDAAVIGVTGADSLTLPGDEIISVEEL
RAVNEAWLPTYMAGPGA
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atgatccgcaacgacatcgccatcacgcccgacctcgtgcgccagcacggcctcaccgac
gaggaatacgcccgcttcaaggagctgatcggccgcgagccgacgatcaccgaactcggc
atcgtctcggcgatgtggaacgagcactgctcctacaagtcctcccgcatccacctgcgc
acgctgccgaccaaggcgccctgggtgatccaggggccgggcgagaatgccggcgtcatc
gacatcggcgacgggcgcgcctgcgtgttcaagatggagagccacaaccacccgagcttc
atcgagccctaccagggcgcggcgaccggggtcggcggcatcctgcgcgacgtgttcacc
atgggcgcccggccgatcgcggcgctgaacgccctgcgcttcggctcccccgaccatccg
cgcacccgccacctcgtctcgggcgtcgtcgccggcatcggcggctacggcaattccttc
ggcgtgccgaccgtcggcgggtcggtcggcttccaccggcgctacgacggcaacatcctg
gtcaacgccatggcggtcggcctcgcccgcgccgacgcgatcttctacgcggccgccacc
ggggtcgggaacccgatcgtctatctcggctccaagaccggccgcgacggcatccacggc
gccaccatggcctcggccgccttcgacgaatcctccgaggagaagcgcccgaccgtgcag
gtcggcgatcccttcgcggagaagctgctgctcgaggcctgcctggagctgatggcctcc
ggcgccgtgatcgcgatccaggacatgggcgcggccggcctgacctgctcggcggtcgag
atgggcgccaagggcaatctcggggtcgaactcgacctcgacgcggtgccgacccgcgag
gcgggcatgactgcctacgagatgatgctctccgagagccaggagcgcatgctcatggtg
ctcaagcccggcatggaggaggaggccaaggcgatcttcgtgaagtggggcctcgacttc
gcgatcatcggccacaccaccgacacgctgcgcttcgtcatcaagcacggcggcgagacg
gtcgccgacctgccgatcaaggagctcggcgacgaggccccgctctacgaccggccgcac
cgcacgaacatgcaccacccggtcctcagggccgaggacgtcccggccccggtgacgcac
ggcgaagccctgcggaggctgatgggctcgcccgacctcgcctcgaagcgctgggtctgg
gagcagtacgaccactacatcctcggcaacacggtccagaagccgggcggcgacgccgcc
gtggtgcgggtcgaggacgggccgaagggcctcgcgctcaccaccgacgtgacgccgcgc
tactgcgaggccgacccggtcgagggcggccgccaggcggtggccgaggcctaccggaac
atctcggcggtgggcggccggccgctcgccgtcaccgacaacctcaatttcggcaatccc
gagaagcccgaggtgatgggccagttcgtcggctgcatccagggcatcggcgaggcctgc
cgcgccctcgacttcccggtcgtgtccggcaacgtctccctctacaacgagaccaacggc
gtcggcatcctgccgaccccgacgatcggcggcgtcggcgtcgtcgacgacgtgcgccgg
atcgccaccctcgccctcaagcgcgagggcgacgcgctggtgctgatcgggcgcagccag
ggctggctcggccagtccctctacctcgccgagatctgcgggcgcgaggaaggcgcgccg
cccccggtcgacctcgccgccgagcggaggaacggcgagttcgtgcgcgggctgatcgcc
tcgggcctcgtcgacaccgtccacgacctctcggatggcggcctcgcggtggcgctcgcc
gagatggcgatggccggccggatcggcgcggcactgcccgaatgcccgctgccgatcccg
gcccacgcctacctgttcggcgaggatcagggccgctacctgctcgcggtcgagcccgag
acggtgcccgacctgctctacagcgccgccgcgcaggggatcgacgccgccgtcatcggc
gtcaccggcgccgattcattgaccctgccgggcgacgagatcatatccgtggaggagctg
cgcgccgtcaacgaggcgtggctgccgacctacatggccgggcccggcgcctga
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