Methylobacterium sp. 4-46: M446_5896
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Entry
M446_5896 CDS
T00679
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
met
Methylobacterium sp. 4-46
Pathway
met00010
Glycolysis / Gluconeogenesis
met00020
Citrate cycle (TCA cycle)
met00620
Pyruvate metabolism
met00785
Lipoic acid metabolism
met01100
Metabolic pathways
met01110
Biosynthesis of secondary metabolites
met01120
Microbial metabolism in diverse environments
met01200
Carbon metabolism
met01210
2-Oxocarboxylic acid metabolism
Module
met_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
met00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
M446_5896
00020 Citrate cycle (TCA cycle)
M446_5896
00620 Pyruvate metabolism
M446_5896
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M446_5896
Enzymes [BR:
met01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
M446_5896
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Ntox3
Motif
Other DBs
NCBI-ProteinID:
ACA20181
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Position
6484433..6485473
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AA seq
346 aa
AA seq
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MEAGSKARREDKTASPPPANAPHFTRDEDVHAYSEMLLIRRFEEKAGQLYGMGLIGGFCH
LYIGQEAVVIGVQMASKEGDQVITGYRDHGHMLACGMDPKGVMAELTGRRGGYSRGKGGS
MHMFSREKNFYGGHGIVGAQVSLGTGLGFANKYRGDGAVSLTYMGDGAANQGQVYESFNM
AELWKLPVVYVIENNRYAMGTSVTRASAQTDFSKRGVSFGIPGEQVDGMDVRAVRDAAAR
AIAHARSGEGPYILEMQTYRYRGHSMSDPAKYRTKDEVARMREESDPIEQVRKRLLGPHK
VPENEIKAIDAQVREIVNEAADFATNDPEPDPAELWTDVLLEPARA
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atggaagccgggagcaaggcacgccgcgaggacaagaccgcgagcccgccccccgcgaac
gcgccgcacttcacgcgcgacgaggacgtgcacgcctacagcgagatgctgctgatccgc
cgcttcgaggagaaggccggccagctctacgggatgggcctgatcggcggcttctgccac
ctctatatcggccaggaggccgtggtgatcggggtccagatggcctcgaaggagggcgac
caggtcatcaccggctaccgcgaccacggccacatgctggcctgcggcatggaccccaag
ggcgtgatggcggaactgaccgggcggcggggcggctattcccgcggcaagggcggctcc
atgcacatgttctcccgcgagaagaacttctacggcggccacggcatcgtcggggcccag
gtctccctcggcaccggtctcggcttcgccaacaagtaccgcggcgacggggcggtcagc
ctgacctacatgggcgacggcgccgccaaccagggccaggtctacgagagcttcaacatg
gcggagctgtggaagctgcccgtcgtctacgtgatcgagaacaaccgctacgccatgggc
acctcggtgacccgggcctcggcgcagacggacttctcgaagcgcggcgtctccttcggc
atcccgggcgagcaggtcgacggcatggacgtgcgcgccgtgcgcgacgccgccgcccgg
gccatcgcgcatgcccggtcgggggaggggccctacatcctggagatgcagacctaccgc
taccgcggccactcgatgtccgacccggccaagtaccggaccaaggacgaggtcgcgcgg
atgcgcgaggaatccgacccgatcgagcaggtccgcaagcggctgctcggcccgcacaag
gtcccggagaacgagatcaaggcgatcgacgcccaggtgcgggagatcgtcaacgaggcg
gcggacttcgccaccaacgaccccgagcccgatcccgccgagctgtggaccgacgtcctg
ctcgagcccgcccgcgcctga
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