KEGG   Methylibium sp. Pch-M: C1M51_00190
Entry
C1M51_00190       CDS       T05827                                 
Symbol
thiD
Name
(GenBank) bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
  KO
K14153  hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
Organism
metp  Methylibium sp. Pch-M
Pathway
metp00730  Thiamine metabolism
metp01100  Metabolic pathways
metp01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:metp00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    C1M51_00190 (thiD)
Enzymes [BR:metp01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     C1M51_00190 (thiD)
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     C1M51_00190 (thiD)
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     C1M51_00190 (thiD)
SSDB
Motif
Pfam: Phos_pyr_kin TMP-TENI PfkB
Other DBs
NCBI-ProteinID: QAZ37962
UniProt: A0A4V0YMJ4
LinkDB
Position
41042..42640
AA seq 532 aa
MTAERTTRPVVWSIAGTDSGGGAGLGADQRAADAFGVHLCPVVSAVTAQNSLAVTRIERL
PPPALEAQLEALADDLPPQVVKTGLLGGVEHVRRVAHWIDRLRRRQPVALVVDPVLAASS
GAAFADPDTLAAYRELLLPRATLITPNRREAAALLGQPEAGTAGLPAQALALRRRGAQAV
CITGGDAADLDGRVLDWMATEQADGWLAAPRIATPHHHGSGCTFASSAAAALALGFVPAD
ALVLAKMATGHALRHAHPAGAGRGPVRAAAGFASDPSLMPWLSWGAAPVFAPAAEPEAPP
ATLGLYAIVDSAARAEQVLAAGVRTLQLRLKTPAVPDTGWQPALRATLQRGIAAARETGA
ALFVNDHWQLAAELGASGVHLGQEDLLALGDEGRARLRASGLALGISSHSLWELARARAL
APRYVACGPVWPTLTKAMPWRPQGLDNLAWWCAMAGRPVVAIGGILTPERVEAAAHCGAD
GVCAVRVLGDDPARVLPSLQRALHAGWQAPTPAPVPALPHPSLTLSVAPRPS
NT seq 1599 nt   +upstreamnt  +downstreamnt
atgacggcggagcgcacgacccgtccggtggtctggagcatcgccggcaccgacagcggc
ggcggcgccggcctcggcgccgaccagcgtgcggccgacgccttcggcgtgcacctctgc
ccggtggtgtcggccgtcaccgcgcagaactcgctcgcggtcacgcgcatcgagcggctc
ccgccacccgcgctcgaggcgcaactggaggcgctggccgacgacctgccgccgcaggtg
gtgaagaccgggctgctcggtggcgtcgagcacgttcggcgggtcgcgcactggatcgac
cggctgcggcgccgccagccggtcgcgctggtggtcgacccggtgctggcggccagcagt
ggcgccgccttcgccgaccccgacacgctggccgcctatcgcgagctgctgctgccccgc
gcgacgctgatcacccccaaccgccgcgaggcggccgcgctgctgggccagcccgaggcc
ggcacggccggcctgccagcgcaggcgctggcgctgcggcgccgcggcgcgcaggcggtc
tgcatcaccggcggcgatgccgccgacctcgacggccgcgtgctggactggatggccacc
gagcaggccgacggctggctcgccgcgccgcgcatcgccacgccacaccaccacggcagc
ggctgcaccttcgccagcagcgcggcggccgccctggcgctcggcttcgtgccggccgac
gcgctggtgctggccaagatggcgaccggccacgcgctgcgccacgctcacccggccggc
gcgggccgcgggccggtgcgggccgcggccgggttcgccagcgatccgagcctgatgccc
tggctgtcgtggggcgctgcgccggtgttcgcgccggctgcggagcccgaggcaccgccc
gccacgctcggcctctacgccatcgtcgacagcgccgcgcgtgcggagcaggtgctggcc
gccggcgtccgcacgctgcagctgcgcctcaagacgccggccgtccccgacaccgggtgg
cagcccgcgttgcgcgccaccctgcagcgcggcatcgccgcagcgcgcgagaccggcgcc
gcgctgttcgtcaacgaccactggcagctcgccgccgaactgggggcctccggcgtgcac
ctgggccaggaggacctgctggcgctgggcgacgagggccgggcgcggctgcgcgccagc
gggctcgcgctcggcatcagctcgcacagcctgtgggagctggcgcgcgcccgcgcgctg
gcgccccgctacgtcgcctgcggcccggtctggcccacgctgaccaaggccatgccgtgg
cggccccagggcctggacaacctggcctggtggtgcgccatggccggccggccggtggtc
gcgatcggcggcatcctgacgcccgagcgggtggaagccgctgcacactgcggcgccgac
ggcgtgtgtgcggtccgcgtgctgggcgacgacccggcgcgcgtgctgccgtcgctgcag
cgcgcgctgcacgccggctggcaggcccccacgccggcgccggtgcccgccctgccgcac
ccctcactcaccctgagcgtcgcaccccggccctcctga

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