Methylobacillus flagellatus: Mfla_0340
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Entry
Mfla_0340 CDS
T00342
Name
(GenBank) dihydroxyacid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
mfa
Methylobacillus flagellatus
Pathway
mfa00290
Valine, leucine and isoleucine biosynthesis
mfa00770
Pantothenate and CoA biosynthesis
mfa01100
Metabolic pathways
mfa01110
Biosynthesis of secondary metabolites
mfa01210
2-Oxocarboxylic acid metabolism
mfa01230
Biosynthesis of amino acids
Module
mfa_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mfa_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mfla_0340
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Mfla_0340
Enzymes [BR:
mfa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
Mfla_0340
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Paralog
Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ABE48611
UniProt:
Q1H4H6
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Position
342511..344361
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AA seq
616 aa
AA seq
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MPQYRSRTSTHGRNMAGARALWRATGMKEDDFQKPIIAIANSFTQFVPGHVHLKDLGQLV
AREIERAGGVAKEFNTIAVDDGIAMGHSGMLYSLPSRDLIADAVEYMVSAHCADALVCIS
NCDKITPGMLMAALRLNIPVVFVSGGPMEAGKVNWQGNMHKLDLVDAMVAAADSNVSDAE
SEAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAARKELFLKAGRLIV
EITKRYYEQDDESVLPRSIANFKAFENAMSLDVAMGGSTNTVLHLLAAAHEAEVDFTMAD
IDRISRGVPCICKVAPATAKYHMEDVHRAGGVMAILSELSRAGLIHRDTPTVHSPTLGEA
LDKWDIMTTNDEDVKKFYRAAPGGISTTIAFSQSMLWPDLDTDRKEGCIRDKDHAYSQDG
GLAVLYGNIALDGCIVKTAGVDDSILKFTGRARIFESQDDAVAAILADKIEAGDIVIIRY
EGPRGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGL
VEENDIIEIDIPNRTIHLAVKDEVLAHRRAAMEARGKDAWKPVNRQRHISVALRAYAAMS
TSAAKGAVRDVSQIEK
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgccgcaataccgctccaggacctccacccatggccgcaacatggcaggcgcacgcgca
ctctggcgtgctaccgggatgaaggaggacgactttcagaaaccaatcattgcgattgcc
aattctttcacccaatttgttcccgggcacgtacacctcaaggatttgggacagctggtg
gctagggagatcgagcgtgcgggtggcgtcgccaaggaattcaacacgattgccgtggat
gatggcattgccatgggccatagcggcatgctgtacagcttgcccagccgtgacctgatt
gccgatgccgtggagtatatggtgagcgcccactgcgccgatgcgctggtgtgcatctcc
aactgtgacaagatcactcctggcatgctcatggcggcgctacgcctgaatattcccgtg
gtattcgtctcgggcgggccgatggaggccggcaaggtcaattggcagggcaatatgcac
aagctcgacctggtggatgccatggtcgctgctgcagacagcaatgtgtccgatgcggag
tccgaggcgatcgaacgttctgcctgcccgacctgcggttcctgttccggcatgttcacc
gccaactcgatgaactgcctgaccgaggcgctcggcctgagcctacctggtaacggctcc
acactggccacgcatgctgcgcgcaaggagctgttcctcaaggctggtcgcctgatcgtg
gaaatcaccaagcgctactacgaacaggatgacgagagtgtactgccgcgcagcattgcc
aacttcaaggcattcgagaatgccatgagcctcgacgtcgccatgggcggctcgaccaac
actgtattgcatttgctggcagcggcgcacgaggctgaggtggatttcaccatggctgac
attgaccgtatttcccgcggcgtgccctgcatatgcaaggtggcacctgctacggccaaa
tatcacatggaggatgtacatcgtgcaggtggcgtgatggccatcctgtcagagttgagt
cgggccgggctgatccaccgtgacactcccaccgtgcacagtccaaccctgggtgaggcg
ttggataagtgggacatcatgaccaccaacgacgaggatgtgaagaaattttatcgtgcc
gcacctggcggtattagcacgacgatcgcattcagccagtccatgctctggccggacctg
gacactgaccgcaaggaaggctgcatccgcgacaaggatcatgcgtattctcaggatggc
ggactggcagtgctttacggcaacattgccctagacggctgtatcgtgaagacggccggc
gtggacgacagcattctcaagttcacggggcgcgcgcgcatttttgaaagccaggatgat
gccgtggctgccattcttgcagacaagatcgaagcgggggacatcgtcatcatccgctac
gaaggcccgcgcggcggacctggcatgcaggaaatgctttacccgaccagctacctcaaa
tccaagggacttggcaaggcatgcgcgctgctgaccgatggccgcttttccggcggtacc
tccggtctgagtatcggccatgcctctccggaagctgccgaaggcggcgcaatcggcctg
gtggaggaaaacgatatcatcgagatcgacattcccaatcgtactattcatctggcggtc
aaggacgaagtgcttgcccaccggcgcgctgccatggaggcacgcggcaaagatgcatgg
aagccggtcaaccgccagcgtcatatatccgttgcattgcgtgcgtatgctgccatgagc
acgtccgcggccaagggggctgtgcgtgacgtcagccagatcgagaagtag
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