Methylobacillus flagellatus: Mfla_0887
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Entry
Mfla_0887 CDS
T00342
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mfa
Methylobacillus flagellatus
Pathway
mfa00230
Purine metabolism
mfa01100
Metabolic pathways
mfa01110
Biosynthesis of secondary metabolites
Module
mfa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mfa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Mfla_0887
Enzymes [BR:
mfa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Mfla_0887
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ABE49155
UniProt:
Q1H2I8
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Position
926877..930770
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AA seq
1297 aa
AA seq
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MSSPMISLRGSAALSPFRIEKILAALKGSAPRITHLYAEFWHFAWSDQPLSEAQQEVLKQ
ILTYGPRMSEEAPAGELFLVIPRPGTISPWSSRATDIARHCGIEAIQRLERGIAFYAATA
DGSPLTDAEKAALRPLIHDRMTEAVFASLTDAQKLYHTAEPAPLSTVDILSGGKAALEAA
NAEMGLALSPDEVDYLIENFQRMGRNPTDVELMMFAQANSEHCRHKIFNADWVIDGVAQA
QSLFGMIRNTHKLNPGKTVVAYADNASIVEGGKTKRFYPLADGQYGFVEEDMHFLMKVET
HNHPTAISPFAGAATGAGGEIRDEGATGSGSKPKAGLTGFSVSNLHIPGFKQPWEHNNGK
PDRIASALQIMVDGPLGGAAYNNEFGRPNIAGYFRTLEIESAGEIRGYHKPIMLAGGVGN
ISARHAKKNPIPPGAALIQLGGPAMLIGLGGGAASSMDTGANTENLDFDSVQRGNPELER
RAQEVIDRCWQLGDKNPILSIHDVGAGGISNAFPELVNDAGVGARFQLRDVHNEEPGMSP
REIWSNEAQERYVMAVRKEDLPLFAEICERERCPFAVVGEATEEKRLVVSDRHFGNTPVD
MDLSVLLGKPPKMTRDVQHVARELPAFDHSRIDLKEAAQRVLRLPGVADKTFLITIGDRS
VTGMIARDQMVGPWQVPVADVAVTLDGFETYRGEAFAIGEKAPLALIDAPASGRMAIGEA
ITNIAASLIEDIADLKLSANWMAPAGHPGEDAALFDTVKAVGMELCPQLGISIPVGKDSM
SMKTVWEERNEKKAVTAPISLVVTAFAPTADARKTLTPQLRTDLGDTRLLLIDLGAGRNR
LGGSALAQVYGSVGNVAPDVEDADSLKHFFNAVQKLNREGRLLAYHDRSDGGLFATVVEM
AFAGRTGLELDIASLGEDAVAVLYNEELGAVLQVRAADLDAITAELETTLRGKVHVIGAP
ASHGDIVIRQGTKLVFAESRVALHRAWSETTYQMQKLRDNPVCAQQEYDRLLDERDAGLH
AKLTFDINENIAAPYIASGARPKMAILREQGVNGQVEMAAAFDRAGFNAFDVHMSDIISG
RVSLKDFAGFVACGGFSYGDVLGAGEGWAKSILFNPRARDEFTAFFNRTDSFALGVCNGC
QMMSNLHSIIPGAGHWPHFVRNRSEQFEARVAMVEVLDSPSLFFNGMAGSRMPIAVAHGE
GYAEFADAAAQQRAQDARLVTLRYVDNSGLPTEVYPFNPNGSPQGITGLTTADGRFSIMM
PHPERVFRTVQHSWHPDGWGEDGPWIRMFRNARKFIG
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcccaatgatcagtcttcgtggcagtgccgctttatctccgttccgtatcgag
aaaatcctggctgcgctgaaaggttcagcgccgcgcatcacgcatttgtacgcagaattc
tggcatttcgcctggtctgaccagccactgagcgaggcgcagcaggaggtgttgaagcag
atcctgacctatggaccgcgcatgagcgaagaggcgccggcgggcgagctgttcctggtg
attccgcgccccgggacgatttctccctggtcctcacgcgccacggatattgcgcgccat
tgcggcatcgaggccatccagcgcctggaacgcggcattgcgttttacgctgccactgcc
gatggcagcccgctcacggatgcggaaaaagctgcattgcgacctttgattcatgaccgc
atgacagaggcggtgtttgcctccctgacagatgcgcaaaagctgtatcacacggcagag
cccgcgcccttatccactgtggatatcctctccggcggcaaggccgcgctggaggccgcg
aatgccgagatgggcctggcgctttccccggatgaggtggattacctgatagagaatttc
caacgcatgggccgcaacccgaccgatgtggaactgatgatgtttgcacaggccaattcc
gagcactgtaggcataagattttcaatgcagactgggtgatcgacggtgtggcacaggca
cagtctctgttcggcatgattcgcaatacacacaagctcaaccctggcaagacggtagtg
gcctatgccgacaatgcatccatcgtcgagggtggcaagaccaagcgcttctatccgctg
gcggatggccaatacggctttgtggaagaggatatgcatttcctcatgaaagtggaaacc
cataaccacccgaccgcgatctcgccatttgcgggtgccgcgaccggtgcgggcggagaa
atacgcgacgagggtgcgaccggatccggctccaagcccaaggccggcctgaccggtttc
tcggtgtccaatctgcatatccccggcttcaagcagccctgggagcataacaatggcaag
cccgaccgcatcgcttcggcattgcagatcatggtggacggcccgttgggcggggcggcc
tacaacaatgagttcggccgtccgaatatcgcaggttatttccgcaccctggaaattgag
tccgcaggagaaattcgcggctatcacaagcccatcatgcttgcgggcggtgtgggcaat
atctctgccaggcatgcgaagaagaacccgattcccccgggggcggcgctgatccaacta
ggtggccccgcgatgctgatcggcctggggggcggtgcggcatcaagcatggataccggg
gctaataccgagaacctggatttcgattccgtgcagcgcggcaaccccgagctggagcgc
cgtgcgcaggaggtcattgaccgttgctggcagttgggcgacaagaacccgatcctgagc
atacacgacgtcggcgccggcggcatttccaatgccttccctgagctggtgaacgatgcc
ggcgtgggcgcgaggttccagttgcgcgatgtgcacaacgaggagcccggcatgtcgccg
cgcgaaatatggagcaatgaggcgcaggagcgctacgtgatggcggtacgcaaggaggat
ttgccattgtttgcggaaatctgcgaacgcgagcgctgcccatttgccgtggtaggcgag
gcgaccgaggagaagcgcctggtcgtgtccgatcgtcatttcggcaataccccggtggac
atggatttgtccgtgttgctgggcaagccgcccaaaatgacgcgggacgtccagcatgtg
gcgcgtgagctgccagccttcgatcattcccgcatcgacttgaaggaagctgcccagcgt
gtgctgcgcctgcctggcgtggcggacaagactttcctgatcaccattggtgaccgctct
gtgaccggcatgatcgcgcgcgaccagatggtcggtccctggcaagtgccagtggctgat
gtcgcagtgacactggatggtttcgagacttatcgcggcgaggccttcgccatcggtgaa
aaagcgcccctggcgctgattgacgcacctgcttcgggccgcatggcgattggcgaggcg
attaccaatatcgctgccagcctgatcgaggatattgcagacctcaagctttccgccaac
tggatggcgcctgccggccacccgggtgaagatgctgccttgttcgataccgtcaaggcc
gtgggtatggagttgtgtccgcaactgggcatcagcattccggtcggcaaggattccatg
tccatgaagaccgtgtgggaagagcgcaatgaaaagaaggcggtgactgcgcctatatcg
ctggtggtcactgcctttgccccaacggccgatgcgcgtaagaccttgacgccgcagctg
cgcactgacttgggcgatacccgcctgctcctgatcgacctgggtgcgggcaggaatcgc
ctgggtggctctgcccttgcgcaggtctatggcagtgtcggcaatgtggcaccggatgtc
gaggatgcggacagcctcaagcattttttcaatgccgtacagaagcttaaccgtgaaggc
cgcctcttggcctatcatgaccgatccgatggcggcttgtttgccactgtggtggaaatg
gcctttgccggacgtaccggcctggagctcgacattgccagccttggcgaggatgccgtg
gcagtgctctataacgaagaactgggtgccgtattgcaggtgcgtgctgccgacctggac
gccattaccgccgagctggagacaaccctgcgcggtaaggtccatgtgatcggcgcgcct
gccagccatggcgatattgtgatccggcaaggcactaagctggtgtttgccgaaagccgc
gtggcattgcaccgtgcctggtcggaaactacctaccagatgcagaagctccgcgacaat
ccagtatgcgcgcagcaggaatatgaccgcttgttggacgagcgcgatgccggcctgcat
gccaagctcaccttcgacatcaacgagaatattgccgcaccttatatcgcttcgggcgcg
cgccccaagatggcgatcctgcgcgaacagggcgtcaatgggcaggtggagatggcggcg
gcattcgatcgcgctggcttcaatgctttcgatgtgcacatgagcgacattatcagcggg
cgtgtcagcctcaaggatttcgccggcttcgttgcctgtggcggcttttcctacggagac
gtgctcggtgccggtgagggctgggccaagtccatcttgttcaatccgcgtgcgcgcgac
gagtttaccgcattcttcaaccggacggattcgttcgcgctgggcgtctgcaacggttgc
cagatgatgagcaacctgcacagcattattcccggtgccgggcactggccgcattttgtg
cgtaaccgttccgagcagttcgaagcacgtgtcgccatggtggaagtgctggactcgcca
tcgctgttcttcaacggtatggctggcagccggatgccgatcgccgtggcgcatggcgaa
gggtatgccgaatttgccgatgcagcagcgcagcaacgcgcacaagatgcgcgattggtg
acgctgcgctatgtcgataatagcgggcttccgaccgaagtatatccatttaacccgaat
ggctcgcctcagggaattaccggcctgactaccgctgatggccgtttcagtattatgatg
cctcatcctgaacgggttttccgcaccgtgcagcactcctggcatcccgatggttggggt
gaggatgggccgtggattcggatgttccgcaatgccaggaagttcattggctag
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