Candidatus Methylacidiphilum fumarolicum: MFUM_0359
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Entry
MFUM_0359 CDS
T09357
Symbol
cimA
Name
(GenBank) (R)-citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mfh
Candidatus Methylacidiphilum fumarolicum
Pathway
mfh00290
Valine, leucine and isoleucine biosynthesis
mfh00620
Pyruvate metabolism
mfh01100
Metabolic pathways
mfh01110
Biosynthesis of secondary metabolites
mfh01210
2-Oxocarboxylic acid metabolism
mfh01230
Biosynthesis of amino acids
Module
mfh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mfh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MFUM_0359 (cimA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MFUM_0359 (cimA)
Enzymes [BR:
mfh01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MFUM_0359 (cimA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
CAI9084753
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Position
MFUM:367568..369157
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AA seq
529 aa
AA seq
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MHTAATNQLVLYDTTLRDGAQGEDIHFSLSDKLRIAKRLDEFGIAYIEGGWPGSNPKDFS
FFSQVKSLNLKQAKIAAFGSTRKAMLAVEEDQQIRLLLEAQSPVVTIVGKSWLLHVLEVL
RTSEKENLAMIRDSVQFLKSHGREVIFDAEHFFDGYKSNKEYALQCIKAAEEAGADFIVL
CDTNGGSLPWEIGQITSEVCSSCKVPIGIHTHNDGELAVANALWAIKSGARQVQGTINGY
GERTGNCNLISVIANLELKMGQKVLPDGKLKELRELSLFVDEIANVRPNPKAPFVGRSAF
AHKGGTHVNALQKLLRSYEHIDPALVGNHRRILVGELSGKSNIVLKAKELGIALEENNPN
IQRVLNKIKELEAKGYEFESAEASFALLLRKLLSPYPSFFHLLEYHVSIRQLPSKNYKVC
EATIKISIHGERVYTVAEGDGPVHALDRALREALVKFYPAIGQLRLEDYKVRIIDSTEGT
ASSIRVWVESTDGKEIWSTVGVSHDIVEASWLALFDSIEYWLLKKTENG
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcatacggctgcaacaaatcaattggtgctttatgacacgaccttaagagatggagca
caaggagaagatattcacttttctctttctgataagcttcgaattgctaaaaggttggat
gagtttggcatagcctatatagaaggaggatggccaggcagtaatcctaaggatttttct
ttttttagtcaggtaaaaagtttgaacttaaaacaagcaaagattgctgcttttggtagc
accagaaaggccatgcttgctgtagaagaagaccaacagataaggcttttgttggaagcg
caaagccctgtggtaacgatcgttgggaaaagttggctgctgcatgttttagaagtgttg
aggacctctgaaaaagaaaatcttgcgatgatccgagactctgtccaatttttaaaatcc
cacggccgagaggttatctttgatgccgaacatttttttgacggttataaatcgaataag
gagtatgccctccaatgcattaaagcggccgaggaggcgggggcggatttcatcgtgctt
tgtgataccaatgggggcagcttgccatgggaaattggacaaattacctctgaggtctgt
tcgagttgtaaggtgcctattgggattcatacgcataacgatggagagctggccgttgct
aacgccctttgggcaataaaatctggagcacgtcaagtccaagggacaatcaatggttat
ggggaaagaactgggaactgtaatcttatatctgttatcgcgaatcttgaactgaaaatg
ggacaaaaagttcttccagatggaaaactcaaagaactaagagaactgtctttatttgtc
gatgaaattgcgaatgtgcgccccaatccgaaggcgccttttgttggtagatctgcattt
gcccataagggggggacgcatgtcaatgccttgcagaaactactaagaagctatgaacat
attgatccagctcttgttggaaatcatcggaggattctggttggagaactttctggtaaa
tccaacattgttcttaaggcaaaggagcttggaattgctttagaagagaataatcctaat
atccaacgggtgcttaataaaattaaggagttggaagccaaaggatatgaatttgaatca
gcggaagcctcttttgccttgcttctgcgtaaactcctttctccttatccatcctttttc
catttactagaatatcatgtgtcgatccgacaactgccttcaaagaattacaaagtctgc
gaggcgaccataaagatatccatccatggagaaagggtctacacggtcgctgagggggat
gggcctgtgcatgccctcgatagagctttgcgtgaggcattggtaaaattttatcctgct
atcggtcagctccggctggaagactataaagtacggattattgattcaacggaaggaacg
gcttcttcgattcgcgtatgggttgaatcaactgatggcaaagagatttggtcaaccgta
ggcgtttctcatgatattgttgaggcttcctggctggcgctcttcgatagtatagaatac
tggttattgaaaaaaactgaaaatggataa
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