Candidatus Methylacidiphilum fumarolicum: MFUM_1696
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Entry
MFUM_1696 CDS
T09357
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mfh
Candidatus Methylacidiphilum fumarolicum
Pathway
mfh00300
Lysine biosynthesis
mfh00550
Peptidoglycan biosynthesis
mfh01100
Metabolic pathways
mfh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mfh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MFUM_1696 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MFUM_1696 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MFUM_1696 (murF)
Enzymes [BR:
mfh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MFUM_1696 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAI9086026
LinkDB
All DBs
Position
MFUM:complement(1638659..1640038)
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AA seq
459 aa
AA seq
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MEQLSVEQIAEWTQGRVIGGKGSVMVGSISTDSRTVKEGDCFLALKGEKYDGLDYVATAA
QKGAVAAIVDRELPLSIPLSIPVIRVKNTLEALQQLAFFYRKQLHAKIIAITGSNGKTST
KEMISSVLRVKYKTVSTSGNLNNQIGLPLSILQMDHTTEYGVFELGTNHCGEIASLSRIV
APDIAIITNIGSAHVGNFGSVEAIGWEKTDLLTFVSPKGFSILMEDDEWSKRLSVRSAGQ
VIWVGNQENSLCWLDQIWLTLKGIRCGISRRGESFEVSLATVSREMAKNALFAAAVGFLS
SLSSKEIALGLEKTVFPLGRLTVHPIRMGYLIDDSYNANLQSTMSALRALTEFPFESEKI
AVLGSMGELGEHAKALHYKLGVFAGSLPLSFIVFIGPHWKDMVEGVKDAGFPLNAVLGTE
DQEEACFQLQKHLNCKLTLLIKGSRFLKLDRIVEKLLSV
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggagcagctttcagttgaacaaattgcggaatggactcaagggagggtcattggggga
aaaggatcggtcatggttggttcgatcagcactgattctaggacagtcaaagaaggagac
tgttttctggctttgaagggagaaaaatatgatgggttggattatgtagccacggcagct
cagaaaggggctgttgctgctatagttgatcgtgagcttcctttgtctattcctctatcg
attcctgttattcgggtaaaaaatacgcttgaggcattgcagcaattggccttcttttac
agaaaacaactacacgcaaagattatagccattacgggtagcaatggaaagactagcact
aaggagatgatttccagtgtattgcgcgtaaaatacaaaactgtttctacttctggaaat
ctaaataatcaaataggactccctctttctatattgcaaatggatcatacaactgaatat
ggggtctttgaactgggaactaatcattgtggagaaattgcttcccttagtcgaattgtt
gcacctgatatagccattatcaccaacattggcagtgcgcatgtgggcaatttcggttct
gtggaagcgattggatgggaaaaaacggatttgttgacttttgtttctcctaaaggattt
tcgattctaatggaggatgacgaatggtccaaacggttgagcgttcgtagtgctggacaa
gttatttgggtagggaaccaagaaaattcactgtgttggctggatcagatttggttgact
ctaaagggtattcgctgtggaatttctcgtcgtggagaaagctttgaagtttctcttgcg
accgtttccagagaaatggcaaaaaatgctctctttgctgcggctgttggttttttgtcc
tctctttcctctaaagaaattgctttggggcttgaaaaaacggtttttcctcttggtaga
cttacggtgcatcccattagaatgggttatctcattgatgatagttacaatgctaatctt
cagtcgactatgagcgccttaagggctcttactgaatttccttttgaatcggagaaaatt
gctgtactaggttctatgggagagttaggagagcatgcaaaagctctccattacaaactt
ggggtgtttgctggtagcttgcccctttcttttattgtttttattggacctcattggaaa
gatatggtggaaggagttaaggatgctggtttcccgcttaatgcagtattggggacagag
gaccaggaagaagcttgttttcagttgcaaaagcatttgaactgcaagctcacactgctt
attaaaggatcgagatttttaaaacttgacaggatcgtcgaaaaacttctttctgtttag
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