Candidatus Methylacidiphilum fumarolicum: MFUM_1930
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Entry
MFUM_1930 CDS
T09357
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mfh
Candidatus Methylacidiphilum fumarolicum
Pathway
mfh00290
Valine, leucine and isoleucine biosynthesis
mfh00660
C5-Branched dibasic acid metabolism
mfh01100
Metabolic pathways
mfh01110
Biosynthesis of secondary metabolites
mfh01210
2-Oxocarboxylic acid metabolism
mfh01230
Biosynthesis of amino acids
Module
mfh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mfh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MFUM_1930 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MFUM_1930 (leuB)
Enzymes [BR:
mfh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
MFUM_1930 (leuB)
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Motif
Pfam:
Iso_dh
AdoMet_Synthase
LacAB_rpiB
Motif
Other DBs
NCBI-ProteinID:
CAI9086252
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All DBs
Position
MFUM:1875578..1876690
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AA seq
370 aa
AA seq
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MKTYRVAVLAGDGIGPELVRVTIPILRLASYLYGFELIFEEALVGGTAIEATGKALPPET
LEICKRAQAIFFGAVGGKQWESLPPEKQPERAALLPLRKTFSLFANLRPITCYPEIIDAS
PLKPEIASGVDLLIVRELTGGIYFGQPKGRVLTEQGERAIDTLLYDTSEIERVATVAFEL
ALRRKKSLTLIDKANVLESSLLWRKTVKEIANNYPEVDLKFMYVDNAAMQLVLKPTQFDV
LLCENLFGDILSDEAAGIAGSLGLLASASIGASKFGLYEPAGGSAPDIAGKGIANPISQI
LSGALMFEYSFQEEEAAQAIKDAVRDVLKEGYRTMDIAKGSATYCTTEEFAEKVAQKIEI
NFKKKKQEGS
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacttatcgcgtcgctgttcttgctggagatggtataggtccggaattggtgcga
gtcactattccaattctacgattagcttcctatctgtacggctttgaactcatttttgaa
gaagccttagtgggaggaacggctatagaagcaacaggtaaagccctgcctccagaaacc
ctggaaatctgcaagcgggcacaagccattttttttggtgcagtaggaggaaaacaatgg
gaaagtctgccgccagaaaaacaacctgagagggctgccttgcttcccctacgaaaaact
ttttcgctttttgccaaccttaggccaattacctgttatccagaaatcatcgacgcttcc
ccccttaaacccgaaatagcttctggggtagacctgcttatcgtaagggaactgacaggg
ggcatttactttggtcagcccaaaggaagggttttaactgagcaaggggaaagagcgatc
gacacgcttctttatgatacctctgaaattgaaagagtggccacagtcgccttcgaatta
gccttgcggagaaaaaagagtttaacccttattgacaaagccaatgttctggaatcgagt
ttattatggaggaagaccgtcaaggaaattgccaataactatcctgaggtcgaccttaag
tttatgtacgtagacaacgcggccatgcagcttgtattaaaacccacacagttcgatgtc
cttctttgcgaaaatctttttggagacatcctcagtgatgaggctgctggcattgctgga
agccttgggcttttagccagtgcttccattggcgctagtaaatttggcttatacgagcct
gccggaggatccgctcctgacattgctggcaaaggaatagctaatcctatttcacagata
ttatccggagcgttgatgttcgaatatagttttcaggaagaagaagctgcccaggctata
aaagatgctgtaagagatgttctaaaagagggatatcgaacaatggacattgctaagggc
tctgctacgtattgtacgaccgaagagttcgctgaaaaagtagctcagaagattgaaata
aatttcaagaagaaaaaacaggaagggagctga
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