Alexandromys fortis (reed vole): 126492432 Help Entry 126492432         CDS       T08493                                  Name (RefSeq) neurofibromin isoform X1   KO K08052   neurofibromin 1 Organism mfot  Alexandromys fortis (reed vole) Pathway mfot01521   EGFR tyrosine kinase inhibitor resistance mfot04010   MAPK signaling pathway mfot04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:mfot00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     126492432    04014 Ras signaling pathway     126492432  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     126492432 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  126492432 NCBI-ProteinID:  XP_049984832 LinkDB All DBs Position Unknown AA seq 2840 aa AA seqDB search MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DLAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKEGFDENNINKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN SALDWWPKIDAVYCHSVELRHMFGETLNKAMQGCGAHPAIRMAPSLTFKEKVTSLKFKEK PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQSSTAELITGLVQLVPQSHMPE IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFFICKKLTSHQMLSSTEILKWL REILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNSSQMSMDHDELLRTCAPGASL RKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE DTHAKWEQATKLILNYPKTKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI NMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRL LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNT QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQAGGRKRGMSRRL ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS FEVDPTRLEPSESLDENQRNLLQMTEKFFHAIISSSSEFPSQLRSVCHCLYQATCHSLLN KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSF ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR KSLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAATYQSVGQTSPRA RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE METQRISSQQHPHLRRVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRIL YEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQ TSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPT SPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSAS QVQKQRSAGSFKRNSIKKIV NT seq 8523 nt NT seq  +upstreamnt  +downstreamnt atggccgcacacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag cttccaataaaaacaggacagcaaaatacacataccaaagtcagtaccgaacataacaag gaatgtctgatcaacatttccaagtacaagttttctctggtcatcagtggcctcaccacc atcttaaagaacgttaacaatatgaggatatttggagaagctgctgaaaaaaatttgtat ctttctcagttgattatattggatacactggaaaaatgtcttgcagggcaaccaaaggac acaatgagattagatgaaacaatgctggtcaaacagttactaccagaaatctgccatttt cttcacacctgtcgtgaaggaaaccaacatgcagctgaacttcggaattctgcttctggg gttttattttctctcagctgcaacaacttcaatgcagtctttagtcgcatttctacaagg ttacaggagttgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta cagtatattaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa tttaaagccctgaagaaggtggcccagttagcagtcataaacagcctagaaaaggccttt tggaactgggtagaaaactatccggatgaatttacaaagctataccaaattcctcagact gatctggctgagtgtgcagaaaagctgtttgacttggtggacggttttgctgaaagcacc aaacgtaaagcagcagtttggccactccaaatcattctcctcattttgtgtccagaaata atccaggatatatccaaagaggggtttgatgagaacaacataaataagaaactgtttctg gacagtttacgaaaagcacttgccggccatggaggaagcaggcagctgactgagagtgct gccattgcttgtgtcaagttgtgtaaagcaagcacttacatcaactgggaagataactct gtcattttcctactagttcagtccatggttgttgatcttaagaacctgctttttaatcca agtaaaccattctctagaggtagtcaacctgcagatgtggacctcatgattgactgtctt gtctcttgctttcggataagccctcataacaaccaacactttaagatatgcctggctcag aattcaccttctacatttcactatgtgttggtaaactcactccaccgcatcataaccaat tctgcattggattggtggcctaagattgatgctgtatattgtcactcagttgaacttcga catatgtttggtgaaacacttaataaagcaatgcagggctgtggagcgcacccagcaata cgaatggcaccaagtcttacatttaaagaaaaagtaacaagccttaaatttaaagaaaag cctacagacctggaaacaaggagctataagtatcttcttttgtccatggtgaaactaatt catgcagatccaaagcttttgctttgtaatccaagaaaacagggccctgaaactcaaagc agtacagcagaattaattacaggccttgtccaactggtccctcagtcacacatgccagag attgctcaggaagcaatggaggccttgctggttcttcatcagttagatagcatcgatttg tggaaccccgatgcccctgtagagacattttgggaaattagttcacaaatgctttttttc atctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctcaagtggtta cgggaaattctgatctgcaggaataaatttcttcttaaaaataagcaggcggatagaagt tcctgtcactttctcttcctttgtggagtaggatgtgatgttcctgctagtggaaatagc tctcagatgtcaatggatcatgatgagttactgcggacctgtgctcctggagcatctctg cggaaaggaaaagggaattcctccatggatagcacagcagggtgcagtggaaccccacca atatgccgacaagcccagaccaagctagaagtggccttgtacatgtttctgtggagccct gacactgaagctgttctggttgccatgtcctgtttccgccatctttgtgaggaagcagat atccggtgtggggtggatgaagtgtcagtacacaacttcttacccaactataacacattc atggaatttgcctctgttagcaacatgatgtcaacaggaagagcagcacttcagaagaga gtgatggccctattaaggcgtattgagcaccccactgcaggaaacactgaggcttgggaa gatacacatgcaaaatgggaacaggctacaaaactaatccttaactatccgaaaaccaaa atggaagatggccaggctgctgaaagccttcataagaccattgttaagaggcggatgtcc catgtcagtggaggtggatccatagatttgtctgacacagactccctgcaagaatggatc aacatgactggcttcctttgtgcacttggtggggtgtgcctgcagcagagaagcagctct ggcttagcgacctacagcccacccatgggccctgtcagtgagcgcaaagggtctatgatt tccgtaatgtcttcagaagggaatgttgatacacctgtcagcagatttatggaccgactt ctgtccttaatggtgtgtaaccatgagaaagtggggcttcagatacggaccaatgttaag gacttggtgggtctggaattgagccctgctctgtatccaatgttgtttaacaaactgaag aataccatcagcaagttttttgactctcaaggacaggtattattgactgatagcaatact cagtttgtagagcaaaccatagccataatgaaaaacctgctggataaccatacagaaggc agctctgagcatctgggacaagctagcattgagacaatgatgttaaatctggtcagatat gttcgtgtgcttggtaatatggtccatgcaattcaaataaaaacaaaactgtgtcagtta gtggaagtaatgatggcaagaagagatgacctctcattttgtcaggagatgaaatttagg aataaaatggtagaatacctaacagactgggttatgggaacatcaaaccaagcagcagat gatgatgtaaagtgtcttacaagagatttggaccaagcaagcatggaagcagtagtttca ctcctcgctggtcttccactacagcctgaagaaggagatggggtggaactgatggaggcc aaatcacagctatttcttaagtacttcacactattcatgaaccttttgaatgactgtagt gaagttgaagatgaaaatgcacaagcaggtggcaggaaacgtggcatgtctcggagactg gcatccctgaggcactgtacagtgcttgcaatgtcaaacttactcaatgctaatgtggac agtggactcatgcactccataggcttaggttatcacaaggatctccagacaagagctacg tttatggaagttctgacaaaaatccttcaacaaggaacagaattcgacacacttgctgaa acagtgttggcagatcggtttgagagactcgtggaactggtcacaatgatgggagatcaa ggagagctccctatagctatggctctggccaatgtggtcccttgttctcagtgggatgag ctggctcgtgttctggttactctgtttgattctcggcacttactctaccagctgctctgg aacatgttttctaaggaagtggaattggcagactccatgcagactctttttcgaggcaac agcttggccagtaagataatgacattctgctttaaggtatacggtgctacttacctacag aagctactggatcctttattgcggattgtgatcacatcttcagattggcagcatgtcagc tttgaagtggatcctaccaggttagaaccttctgagagccttgatgaaaaccagaggaac ctccttcagatgacagagaagttcttccatgctatcatcagttcctcctcagaattcccc tcccagcttcgaagtgtctgccattgcttataccaggcaacttgccactccctactgaat aaagctacagttaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgtttccct cagaacagcatcggtgcagtaggaagtgccatgtttctcagatttatcaatcctgccatt gtctcgccatatgaagcagggattttagataaaaagccgccacctagaattgaaagaggc ttgaagttaatgtcaaagatacttcagagcattgccaatcatgtcctgttcacaaaagaa gagcatatgaggccttttaatgattttgtgaaaagcaactttgacttggcacgaaggttt tttcttgatatagcatcagattgtcccacaagtgatgctgtaaatcatagtctttccttc atcagtgatggtaatgtgcttgctttacatcggctgctttggaacaatcaggagaaaatt ggccagtatctttccagcaacagggatcataaagctgttggaagacgaccttttgataag atggccacacttcttgcatacttgggtcctccagagcacaagcctgtggcagatacacac tggtccagccttaaccttaccagttcaaagtttgaagaatttatgaccaggcatcaggta catgagaaagaagaattcaaggctttgaaaacactaagcattttctaccaagctggtact tccaaagctgggaatcctattttttattatgttgcacggaggttcaaaactggccaaatc aatggtgatttgctgatataccatgtcttgctgactttaaagccatattatgcaaagcca tatgaaattgtagtggatcttacccatactggacctagcaatcgctttaaaacagacttc ctttctaagtggtttgttgtttttcctggcttcgcttacgacaatgtgtctgcagtctat atctataactgtaactcctgggtcagggagtacaccaagtaccacgagcggctgctgact ggcctgaagggcagcaaacggcttatttttatagactgccccgggaagctggctgagcac atagagcatgagcaacagaaactccctgctgccaccttggctctggaagaagacctaaag gtgttccacaatgctctcaagcttgctcacaaagacaccaaagtctctattaaggttggt tctactgctgttcaggtaacctcagcagagagaaccaaagtactggggcaatccgtcttt ctaaatgacatctactatgcttctgaaatcgaagagatctgcctagtggatgagaaccag ttcaccttaaccattgcaaaccaaggcacaccacttaccttcatgcatcaggagtgtgaa gccattgtccagtctatcattcatatcaggacccgctgggagctgtcacagcctgactcc atccctcagcataccaagattcgaccaaaagatgttcctgggacactgcttaatattgca ttacttaatttaggcagttcagaccctagtctacggtctgctgcctataatcttctgtgt gccttaacttgtacctttaatttaaaaattgagggccagttactagagacatcagggtta tgcatccctgccaacaacaccctctttattgtctcaatcagtaagacgcttgcagccaat gagccacacctcaccttagagtttttggaagagtgtatttctggatttagcaaatctagt attgaattgaagcacctttgtttggaatatatgactccatggctgtcaaatctagttcgt ttttgtaaacataatgatgatgctaaacgacaaagggttactgccatccttgataagcta ataacaatgactataaatgagaagcagatgtacccttctattcaagcgaaaatatgggga agccttgggcagatcacagatctgctggatgttgtgcttgacagtttcatcaaaaccagt gctacaggagggttagggtctatcaaggctgaggtgatggcagatacagctgtggctttg gcttctggaaatgtgaaattggtgtcaagtaaggttattggacggatgtgtaaaataata gacaagacttgcttgtctccaactccaactttagaacaacatctgatgtgggatgatatt gctattttagcccgctacatgctgatgctgtccttcaacaactccctcgatgtggcagct catctgccctatctcttccatgttgttacgttcctagtagccacgggtcccttgtccctt cgagcgtccacacatgggttggtcattaatatcattcactctctgtgtacttgttcacaa cttcattttagtgaagagaccaagcaagttttaaggctcagtctaacagaattctcatta cccaaattttacttactgtttggcattagcaaagttaagtcagctgctgtcatcgccttc cgttccagttaccgggaccgatctttctccccaggctcctatgagagggagacttttgct ttgacatccctggaaacagtcacagaggctttattggagatcatggaggcatgtatgaga gatattccaacatgcaagtggctggatcagtggacagaactagcacaaagatttgcattt cagtacaacccatccctgcagccaagagctcttgtggtgtttggctgtattagcaaacgt gtgtctcacgggcagataaagcagattatccgaattcttagcaaggcgcttgaaagctgc ttaaaaggtcctgacacgtacaacagtcaagttctgatagaagccacagtgatagccctg accaaattacagccgcttctcaataaggactccccactgcacaaagccctcttttgggtt gccgtggctgtgctgcagttagatgaagtcaacttgtattcagcaggtactgcacttctg gaacagaacctgcacaccttagatagtcttcggatatttaatgacaagagtccagaagaa gtatttatggcaatccggaatcctctggaatggcactgcaagcaaatggatcactttgtt ggacttaatttcaactctaactttaattttgcactagttggacacctcttaaaagggtac aggcatccttcacctgccattgttgcaagaacagtcagaattttgcatacactgctaact cttgttaacaaacatagaaattgtgacaaatttgaggtgaacacacagagtgtggcttac ttagcagctctactcacagtgtccgaagaggttcgaagtcggtgtagcctcaagcatagg aagtcccttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccatt catcatggtgaccctagctataggacactaaaggagaaccagccatggtcttctcccaaa ggttcagaaggataccttgcagcaacctaccaatctgtaggccagaccagtccccgggcc aggaaatccatgagcttggacatggggcagccttctcaagccaacacaaagaaattgctt ggaacaagaaaaagctttgatcacttgatatcagacacaaaggctcctaaaagacaagaa atggaatcagggatcacaacaccccccaaaatgagaagagtggcagaaactgattacgaa atggaaacccaaaggatttcctcacagcagcacccacatttacggagagtctcagtgtct gaatcaaatgttctattggatgaagaagtacttactgacccaaagatccaagcactgctt cttactgttctggctacactggtaaaatatactacagatgaatttgatcaacgaattctt tatgaatacctagcagaagccagtgttgtgtttcccaaagtgtttcctgttgtgcacaat ttgttggactctaagatcaataccctcttgtcattgtgccaagatccaaatttgttaaat ccaatccatggaattgtgcagagtgtggtgtatcatgaggaatcccctccacagtaccaa acatcttacctgcaaagttttggtttcaatggcttatggcggtttgcaggacccttttca aagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttgatt gacacgtacttgcctggaattgatgaagaagccagtgaggagtccctcctgacacccaca tctccttaccctcctgcactgcagagccagcttagtatcactgccaaccttaacctctct aattccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagaacgtt gaactctcccccaccactggccactgtaacagtggacgaactcgccatggatccgcaagc caagtgcagaagcagagaagtgctggcagtttcaaacgtaatagcattaagaagatcgtg tga

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