KEGG   Alexandromys fortis (reed vole): 126500615
Entry
126500615         CDS       T08493                                 
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mfot  Alexandromys fortis (reed vole)
Pathway
mfot01522  Endocrine resistance
mfot04010  MAPK signaling pathway
mfot04012  ErbB signaling pathway
mfot04014  Ras signaling pathway
mfot04024  cAMP signaling pathway
mfot04068  FoxO signaling pathway
mfot04071  Sphingolipid signaling pathway
mfot04137  Mitophagy - animal
mfot04140  Autophagy - animal
mfot04141  Protein processing in endoplasmic reticulum
mfot04210  Apoptosis
mfot04215  Apoptosis - multiple species
mfot04217  Necroptosis
mfot04310  Wnt signaling pathway
mfot04380  Osteoclast differentiation
mfot04510  Focal adhesion
mfot04530  Tight junction
mfot04620  Toll-like receptor signaling pathway
mfot04621  NOD-like receptor signaling pathway
mfot04622  RIG-I-like receptor signaling pathway
mfot04625  C-type lectin receptor signaling pathway
mfot04657  IL-17 signaling pathway
mfot04658  Th1 and Th2 cell differentiation
mfot04659  Th17 cell differentiation
mfot04660  T cell receptor signaling pathway
mfot04664  Fc epsilon RI signaling pathway
mfot04668  TNF signaling pathway
mfot04722  Neurotrophin signaling pathway
mfot04723  Retrograde endocannabinoid signaling
mfot04728  Dopaminergic synapse
mfot04750  Inflammatory mediator regulation of TRP channels
mfot04910  Insulin signaling pathway
mfot04912  GnRH signaling pathway
mfot04914  Progesterone-mediated oocyte maturation
mfot04917  Prolactin signaling pathway
mfot04920  Adipocytokine signaling pathway
mfot04926  Relaxin signaling pathway
mfot04930  Type II diabetes mellitus
mfot04931  Insulin resistance
mfot04932  Non-alcoholic fatty liver disease
mfot04933  AGE-RAGE signaling pathway in diabetic complications
mfot04935  Growth hormone synthesis, secretion and action
mfot04936  Alcoholic liver disease
mfot05010  Alzheimer disease
mfot05012  Parkinson disease
mfot05016  Huntington disease
mfot05017  Spinocerebellar ataxia
mfot05020  Prion disease
mfot05022  Pathways of neurodegeneration - multiple diseases
mfot05132  Salmonella infection
mfot05133  Pertussis
mfot05135  Yersinia infection
mfot05142  Chagas disease
mfot05145  Toxoplasmosis
mfot05152  Tuberculosis
mfot05161  Hepatitis B
mfot05162  Measles
mfot05166  Human T-cell leukemia virus 1 infection
mfot05167  Kaposi sarcoma-associated herpesvirus infection
mfot05169  Epstein-Barr virus infection
mfot05170  Human immunodeficiency virus 1 infection
mfot05171  Coronavirus disease - COVID-19
mfot05200  Pathways in cancer
mfot05208  Chemical carcinogenesis - reactive oxygen species
mfot05210  Colorectal cancer
mfot05212  Pancreatic cancer
mfot05231  Choline metabolism in cancer
mfot05415  Diabetic cardiomyopathy
mfot05417  Lipid and atherosclerosis
mfot05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mfot00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    126500615
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126500615
   04012 ErbB signaling pathway
    126500615
   04014 Ras signaling pathway
    126500615
   04310 Wnt signaling pathway
    126500615
   04668 TNF signaling pathway
    126500615
   04068 FoxO signaling pathway
    126500615
   04071 Sphingolipid signaling pathway
    126500615
   04024 cAMP signaling pathway
    126500615
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    126500615
   04137 Mitophagy - animal
    126500615
  09143 Cell growth and death
   04210 Apoptosis
    126500615
   04215 Apoptosis - multiple species
    126500615
   04217 Necroptosis
    126500615
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126500615
   04530 Tight junction
    126500615
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    126500615
   04621 NOD-like receptor signaling pathway
    126500615
   04622 RIG-I-like receptor signaling pathway
    126500615
   04625 C-type lectin receptor signaling pathway
    126500615
   04660 T cell receptor signaling pathway
    126500615
   04658 Th1 and Th2 cell differentiation
    126500615
   04659 Th17 cell differentiation
    126500615
   04657 IL-17 signaling pathway
    126500615
   04664 Fc epsilon RI signaling pathway
    126500615
  09152 Endocrine system
   04910 Insulin signaling pathway
    126500615
   04920 Adipocytokine signaling pathway
    126500615
   04912 GnRH signaling pathway
    126500615
   04914 Progesterone-mediated oocyte maturation
    126500615
   04917 Prolactin signaling pathway
    126500615
   04926 Relaxin signaling pathway
    126500615
   04935 Growth hormone synthesis, secretion and action
    126500615
  09156 Nervous system
   04728 Dopaminergic synapse
    126500615
   04723 Retrograde endocannabinoid signaling
    126500615
   04722 Neurotrophin signaling pathway
    126500615
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126500615
  09158 Development and regeneration
   04380 Osteoclast differentiation
    126500615
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126500615
   05208 Chemical carcinogenesis - reactive oxygen species
    126500615
   05231 Choline metabolism in cancer
    126500615
  09162 Cancer: specific types
   05210 Colorectal cancer
    126500615
   05212 Pancreatic cancer
    126500615
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    126500615
   05170 Human immunodeficiency virus 1 infection
    126500615
   05161 Hepatitis B
    126500615
   05171 Coronavirus disease - COVID-19
    126500615
   05162 Measles
    126500615
   05167 Kaposi sarcoma-associated herpesvirus infection
    126500615
   05169 Epstein-Barr virus infection
    126500615
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    126500615
   05135 Yersinia infection
    126500615
   05133 Pertussis
    126500615
   05152 Tuberculosis
    126500615
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    126500615
   05142 Chagas disease
    126500615
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    126500615
   05012 Parkinson disease
    126500615
   05016 Huntington disease
    126500615
   05017 Spinocerebellar ataxia
    126500615
   05020 Prion disease
    126500615
   05022 Pathways of neurodegeneration - multiple diseases
    126500615
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126500615
   05418 Fluid shear stress and atherosclerosis
    126500615
   05415 Diabetic cardiomyopathy
    126500615
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    126500615
   04936 Alcoholic liver disease
    126500615
   04932 Non-alcoholic fatty liver disease
    126500615
   04931 Insulin resistance
    126500615
   04933 AGE-RAGE signaling pathway in diabetic complications
    126500615
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    126500615
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mfot01001]
    126500615
Enzymes [BR:mfot01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     126500615
Protein kinases [BR:mfot01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   126500615
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 126500615
NCBI-ProteinID: XP_049996604
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSPSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctaaaacgataccagaatttaaaacctataggctcaggagctcaaggaatagtg
tgtgcagcttatgatgccattctcgaaagaaatgttgcaatcaagaagctcagccggcca
tttcagaatcagactcatgctaagcgagcctaccgagaactagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagttagatcatgaaagaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattattcaccgggacttaaagcctagtaatatagtagtcaaa
tcagactgcactttgaagattcttgattttggactggcgaggactgcaggaacaagtttt
atgatgacgccttatgtcgtgactcggtactacagagcgccagaggtcatcctcggcatg
ggctacaaggagaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccctgtcctgaattcatgaagaaattacaaccaacagtaaggacttatgtt
gaaaaccgacctaaatatgctggatatagctttgagaaactgttccctgatgtgcttttc
ccagctgactcagagcataacaagcttaaagccagccaggcaagggatttgttatccaaa
atgctagtaatagatgcatccaaaaggatctcagtagatgaagctctccagcacccatac
atcaacgtctggtatgacccttcggaagcagaagccccaccaccaaagatccccgacaag
cagttagatgaaagggagcacacgatagaagagtggaaagaattaatatacaaggaggtg
atggacttggaggaacgaaccaagaatggagtcataagagggcagccatctcctttaggt
gcagcagtgatcaacggctctcagcacccatcgtcttcaccgtctgtcaatgatgtgtct
tcaatgtccacagatccgactttggcctcggatacagacagcagtctagaagcatctgct
ggacctctaggctgctgtagatga

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