Mycolicibacterium frederiksbergense: EXE63_21125
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Entry
EXE63_21125 CDS
T10436
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mfre Mycolicibacterium frederiksbergense
Pathway
mfre00230
Purine metabolism
mfre00670
One carbon pool by folate
mfre01100
Metabolic pathways
mfre01110
Biosynthesis of secondary metabolites
Module
mfre_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mfre00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EXE63_21125 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
EXE63_21125 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mfre04147
]
EXE63_21125 (purH)
Enzymes [BR:
mfre01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
EXE63_21125 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
EXE63_21125 (purH)
Exosome [BR:
mfre04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
EXE63_21125 (purH)
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
MshEN
Motif
Other DBs
NCBI-ProteinID:
QIV83112
UniProt:
A0A6H0S689
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All DBs
Position
3722928..3724487
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AA seq
519 aa
AA seq
DB search
MSDKRPIRRALISVYDKTGLVDLARGLHEAGVSIVSTGSTAKTIAGAGVPVTPVEDVTGF
PEVLDGRVKTLHPKVHAGVLADLRKSEHEAALTDLGIAPFELVVVNLYPFSETVASGAGP
DECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRSGGFTLTERKKLAALAFQ
HTAEYDVAVAAWMVSVLAPEEGSELPRWVGSTSRRTAVLRYGENPHQKAALYRDDSGWPG
LAQAEQLHGKEMSYNNYTDADAAWRAAFDHEQTCVAIIKHANPCGIAVSSVSVADAHAKA
HACDPLSAFGGVIATNSTVSVEMAETVADIFTEVIIAPAYEPGAVEALTKKKNIRILVAA
EPEGAAVDFRPISGGLLVQERDALDAEGDDPNNWTLATGDPADPATLADLVFAWRAGRAV
KSNAIVIAKDGATVGVGMGQVNRVDAARLAVERAGERTRGAVASSDAFFPFPDGLQTLTA
AGVTAIVHPGGSVRDDEVTAAAAEAGITLYLTGARHFAH
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
atgagtgacaagcggccgatccggcgtgcgttgatcagtgtgtacgacaagacggggttg
gtggaccttgcccgcggcctgcatgaggcgggcgtcagcatcgtctccaccggttcgacc
gcgaaaaccattgccggcgccggggtcccggtgacgccggtggaggatgtcaccggtttc
cccgaggtgctcgacggccgcgtgaagacactgcaccccaaggtgcacgccggcgtgctg
gccgacctgcgcaagtccgagcacgaggcggcactgaccgacttgggcatcgcgccgttc
gaactcgtcgtggtgaacctgtacccgttcagcgagacggtggcctccggcgccgggccc
gacgagtgcgtcgagcagatcgacatcggtggcccgtccatggttcgggcggccgcgaag
aaccatcccagcgtcgccgtggtcgtcgacccgctcgggtatgacggtgtgctggccgcg
gtgcgttccggcggattcaccctcacggagcggaagaagctggccgcgttggctttccag
cacaccgccgagtacgacgtggcggtggcggcctggatggtctcggtgctcgccccggaa
gagggctcggaactgccgcgctgggtcgggtcgacctcgcgccgcaccgcggtgctgcgc
tacggcgagaacccgcaccagaaggcggcgctgtaccgcgacgactccggctggccggga
ctggcgcaggccgagcagctgcacggcaaggagatgtcctacaacaactacaccgacgcc
gacgccgcctggcgcgccgcgttcgaccacgagcagacctgcgtggcgatcatcaagcac
gccaatccgtgcggtatcgcggtgtcctcggtgtcggtcgccgatgcgcacgccaaggcg
cacgcctgtgacccgttgtcggccttcggcggagtgatcgccaccaacagcaccgtcagc
gtcgagatggccgagacggtggccgatatcttcaccgaggtgatcattgcgccggcctat
gagcccggcgcggtggaggcgctgaccaagaagaagaacatccgcatcctggtggccgcc
gaaccggagggagcggctgtcgatttccggccgatcagcggcggtctgctggtgcaggag
cgcgatgcactcgacgccgagggcgatgatccgaacaactggacgctggcgaccggcgat
cccgccgacccggcgacgctggccgatctggtcttcgcctggcgcgcgggccgggcggtg
aagtccaatgccatcgtgatcgccaaggacggcgccaccgtcggcgtcggcatggggcag
gtcaaccgggtggatgccgcccggctggcggtcgagcgggcgggtgaacgcacccggggc
gccgtggcgtcctccgatgcgttcttcccgttcccggacggcctgcagacgctgaccgcc
gccggggtgacggcgatcgtgcacccgggtggatcggtgcgcgacgacgaggtgacggcg
gcggccgccgaggccgggatcacgctgtacctgaccggggcacggcacttcgcgcactag
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