Mycolicibacterium frederiksbergense: EXE63_25350
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Entry
EXE63_25350 CDS
T10436
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mfre Mycolicibacterium frederiksbergense
Pathway
mfre00790
Folate biosynthesis
mfre01100
Metabolic pathways
mfre01240
Biosynthesis of cofactors
Module
mfre_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
mfre00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EXE63_25350
Enzymes [BR:
mfre01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EXE63_25350
6.3.2.17 tetrahydrofolate synthase
EXE63_25350
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QIV85515
UniProt:
A0A6H0SGP9
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All DBs
Position
4592803..4594206
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AA seq
467 aa
AA seq
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MNQPAPDEIAALLQVEHLLDQRWPETKIEPSTTRISALLELLGSPQRNYPAIHIAGTNGK
TSVARIIDALLTALHRRTGRIVSPHLQSAVERISIDGKPITPAQYVETYREIEPFIELVD
QQSEAAGGPRMSKFEVLTAMAFAAFADAPIDVAVVETGLGGRWDATNVIGAPVAVITPIG
LDHTDYLGDTIAEIAGEKAGIIIKAEDDLVPIDTVAIIAKQDPEAMEVLLAEAVRADAAV
AREDSEFAVLERQVAIGGQLLTLQGLGGVYPEMFLPLHGLHQAHNAVLALAAVEAFFGAG
ADRQLDVDAVRTGFASVSSPGRLERVRSAPTVFIDAAHNPAGAAALTQALADEFDFRYLV
GVVSVMADKDVDGILAALEPAFDMVVVTDNGSPRAMEVELLAAKAEERFGPERVVAAAAL
PDAIETATALVEESGNDGEGYSGSGMVITGSVVTAGAARTLFGRDPQ
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgaaccagcccgcccccgacgagatcgcggcgctgctgcaggtcgagcatctgctcgac
cagcggtggccggagaccaagatcgagcccagcaccacacggatctccgcactgctggag
ttgctgggctcaccgcagcgcaactacccggcgatccacatcgccggcaccaacggcaag
acatcggtggcccgcatcatcgacgcgttgctgacggcattgcaccggcgcaccgggcgc
atcgtgagcccgcacctgcagtcggcggtcgagcgcatctccatcgacggcaagccgatc
accccggcccagtacgtcgagacctatcgggagatcgaaccgttcatcgagttggtggac
caacagtccgaagcggccgggggtccgcgcatgagcaagttcgaggtgctcaccgcgatg
gcattcgccgcgttcgccgacgcgccgatcgatgtggcggtggtggaaaccgggttgggc
gggcgctgggacgccaccaacgtgatcggcgccccggtcgcggtgatcaccccgatcggg
ctggaccacaccgactacctcggtgacaccattgccgagatcgccggtgagaaggccgga
atcatcatcaaggccgaagacgacctggttccgatcgacaccgtggcgatcatcgccaaa
caggatcccgaggcgatggaggtgctgctggccgaggcggtgcgcgccgatgccgcggtg
gcgcgcgaggattcggaattcgcggtcctggagcgtcaggtcgccatcggcggtcagctg
ttgaccttgcagggactcggcggggtgtatccggaaatgttcctgcccctgcacggtttg
caccaggcgcacaacgccgtgctcgcgctggccgcggtcgaggcgttcttcggggccggc
gccgaccgtcagctcgatgtcgacgcggtgcgcaccggcttcgcctcggtgagcagcccg
ggccggctggaacgggtgcgcagcgcgccgacggtgttcatcgacgccgcccacaatccc
gccggcgccgcggccctgacccaggccctggctgacgagttcgacttccgctacctggtc
ggcgtggtgtcggtaatggcggacaaggacgtcgacggcatcctcgcggcgctggagccc
gcgttcgacatggtcgtggtcaccgacaacggttcaccccgggcgatggaggtggaactg
ctcgccgccaaggccgaggagcggttcggcccggaacgggtggttgcggccgccgcgctt
cccgatgccatcgagaccgcgacggcgctggtggaagagtccggcaacgacggcgaagga
tattcggggagcggcatggtcatcaccggttcggttgtcaccgcgggtgcggcgcgcacc
ctgttcgggcgggatccacagtga
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