Methanocaldococcus sp. FS406-22: MFS40622_0827
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Entry
MFS40622_0827 CDS
T01175
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mfs
Methanocaldococcus sp. FS406-22
Pathway
mfs00290
Valine, leucine and isoleucine biosynthesis
mfs00620
Pyruvate metabolism
mfs01100
Metabolic pathways
mfs01110
Biosynthesis of secondary metabolites
mfs01210
2-Oxocarboxylic acid metabolism
mfs01230
Biosynthesis of amino acids
Module
mfs_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mfs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MFS40622_0827
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MFS40622_0827
Enzymes [BR:
mfs01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MFS40622_0827
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
URO-D
Radical_SAM
Imm74
Motif
Other DBs
NCBI-ProteinID:
ADC69510
UniProt:
D3S3U6
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All DBs
Position
complement(825803..827359)
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AA seq
518 aa
AA seq
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MIIYRDENEIIKKALENLNIPDRVYIFDTTLRDGEQTPGVSLTPEEKIEIAIKLDDLGVD
VIEAGFPVSSLGEQEAIKKICSLNLDAEICGLARAVKKDIDVAIDCGVDRIHTFIATSPL
HRKYKLKKSKEEIINIAVEAIEYIKEHGIRVEFSAEDATRTELDYLIEVYKKAVEAGADI
INVPDTVGVMIPRAMYYLISELKKEIKVPISVHCHNDFGLAVANSLAAIEAGAEQVHCTI
NGLGERGGNAALEEVVMSLMSIYGVKTNIKTEKLYEISQLVSKYTEIKVQPNKAIVGENA
FAHESGIHAHGVLAHALTYEPIPPELVGQKRKIILGKHTGTHAIEAKLKELGIEVGKDIN
KEQFDEIVKRIKALGDKGKRVTDRDVEAIVEDVVGKLAKEERVVELEQIAVMTGNRVIPT
ASVALKIEEEIKKSSAIGVGPVDAAVKAIQKAIGEKIKLKEYHINAITGGTDALAEVIVT
LEGYGREITTKAASEDIVRASVEAVIDGINKILVKKEK
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgataatttatagggatgagaatgagattataaaaaaagcccttgaaaacctaaatatt
ccagatagagtttatatctttgacacaacacttagagatggtgagcaaactcctggagta
tctctaacaccagaggaaaagatagaaattgccataaaattagatgacttaggagttgat
gttattgaagctggatttccggtatcttccttaggagagcaggaggcaattaaaaaaatc
tgctcactaaacttagatgctgaaatctgtggattggcaagggctgttaagaaagatata
gatgtagctattgactgcggagttgatagaatccacacatttatagcaacctctccattg
cacagaaaatacaaactaaaaaaatctaaggaggaaattattaacatagcagttgaggct
atagagtatataaaagaacatggaattagagtagagttttcagcagaagacgctacaaga
actgagcttgattatttaatagaggtctataaaaaggcagttgaagctggagcagatata
atcaacgtcccagatacagttggtgttatgattccaagagctatgtattatttaataagt
gagttaaagaaggagataaaagttcctatatctgtgcattgccataatgactttggtttg
gctgttgctaattcattagctgctatagaagctggagcagagcaagttcattgcacaatc
aacggtttaggagagagaggaggaaatgctgccttagaagaggtagttatgagcttaatg
tcaatttatggtgttaaaactaatattaaaactgagaaattatatgagatatctcaactt
gtatcaaaatacactgaaattaaggttcaaccaaacaaggcaatcgttggagaaaacgct
ttcgctcacgagagcggaatacatgcacacggagttttagctcatgcactaacctatgag
cctatccctccagaattagttgggcagaagagaaagataatattaggtaagcacactggg
acacatgcaattgaggcaaagttaaaagagttgggaattgaggttggtaaagatataaat
aaagagcagtttgatgagatagttaagagaattaaagcccttggagataaggggaagaga
gttactgacagagatgttgaggcaatcgttgaggatgttgttggtaagttagctaaagaa
gagagagttgttgaattagagcagatagcagttatgactggaaatagggttattccaact
gcatcagttgctttaaagattgaagaagagattaagaaaagctcagctattggtgttggg
cctgtagatgcggcagttaaagcaatacaaaaagcaattggggagaagattaaacttaaa
gagtatcatataaatgccataactggaggaactgatgcattggcagaggttatcgtaacc
ttagaaggatatggtagggagataacaacaaaagcagcaagtgaggatatagttagagct
tcagttgaggcagttatagatggaataaacaagatcttggtaaaaaaagaaaaataa
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