Mycolicibacterium fallax: MFAL_12310
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Entry
MFAL_12310 CDS
T06894
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mfx
Mycolicibacterium fallax
Pathway
mfx00300
Lysine biosynthesis
mfx00550
Peptidoglycan biosynthesis
mfx01100
Metabolic pathways
mfx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mfx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MFAL_12310 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MFAL_12310 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MFAL_12310 (murF)
Enzymes [BR:
mfx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MFAL_12310 (murF)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBY97764
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Position
complement(1284589..1286133)
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AA seq
514 aa
AA seq
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MIALTLAEIADIVGGRLADIDDAAAAATRVTGTVEFDSRAVTSGGLFLAMPGARTDGHDH
AAAAIAAGAVAVLAARPVGVPAIIAPPAAGPAGAGVLEHDRDGSGAAVLAALAKLAAEVA
RRLTADGLTIIGVTGSSGKTSTKDLLAAVLAPLGEVIAPPGSFNNELGHPWTVLRATTST
DYLILEMSARHPGNIAALARIAPPSIGVVLNVGTAHLGEFGSRQAIADTKAELVQAVGAS
GAVVLNADDPAVDAMAEQTAARVIRVSRAPGTGIGLWATDVVLDGLARPRFRLHRPDGDA
VPVALAVHGDHQVSNALCAAAVALECGADLTQVADALAGAGPVSARRMQVSTRADGVTVV
NDAYNANPDSMTAGLKALAWMARGEPGAERRRSIAVLGEMAELGEDAIAEHDRIGRLVVR
LDVSQLIVVGTSRPMGAMFNGAVMEGSWGSEAIAVEDAAAALELLRTELRPGDVVLVKAS
NSAGLGALAETVAADIAGDPGARHPGPVRDDAPR
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcgctgaccctcgccgagatcgccgacatcgtcggcggccggctcgcggacatc
gacgacgccgccgcggcggccacccgggtcaccgggaccgtcgaattcgattcccgcgcc
gtcacttccggcggcctgttcctggcgatgccgggtgcgcgcaccgacggccacgatcac
gccgccgcggcgatcgccgccggtgcggtggcggtgctggccgcccggccggtcggggtg
ccggcgatcatcgccccgccggcggccgggcccgccggggccggggtgctcgaacacgac
cgggacggctccggcgcggcggtgctggccgcgctggccaagctggccgccgaggtggcc
cgccggctgaccgccgacgggctgaccatcatcggggtgaccggctcgtcgggcaagacc
tcgaccaaggacctgctggccgccgtgctggcgccgctgggggaggtgatcgcgccgccc
ggatcgttcaacaacgagctcggccatccctggacggtgctgcgcgccaccacctcgacc
gattacctgatcctggagatgtcggcccggcaccccggcaatatcgcggcgctggcccgg
atcgcgccgccgtcgatcggggtggtgctcaacgtcggcaccgcccacctcggtgagttc
ggttcgcgccaggccatcgccgacaccaaggccgagctggtccaggccgtcggggccagc
ggggcggtggtgctcaacgccgacgatcccgccgtcgacgcgatggccgagcagaccgcc
gcccgggtgatccgggtgtcccgggcgcccgggaccggcatcgggctgtgggccaccgac
gtcgtgctcgacgggctggcccgcccgcggttccggctgcaccggcccgacggcgacgcc
gtgccggtcgcgctggccgtgcacggcgaccatcaggtgtccaacgcgttgtgcgcggcc
gcggtcgcgctggaatgcggcgccgacctgacccaggtggccgacgcgctggccggcgcc
gggccggtgtcggcccgccggatgcaggtcagcacccgtgccgacggcgtcaccgtcgtc
aacgacgcctacaacgccaaccccgattcaatgaccgccggcctcaaggcgctggcctgg
atggcccgcggggaacccggcgccgagcggcggcgcagcatcgcggtgctcggcgagatg
gccgagctgggggaggacgcgatcgccgaacacgaccggatcggccggctggtggtgcgg
ctggacgtgtcccagctgatcgtcgtcggcacctcccggccgatgggcgcgatgttcaac
ggcgcggtgatggagggctcgtggggcagcgaggcgatcgccgtcgaggacgccgcggcc
gccctcgagctgctgcgcaccgaactgcggcccggtgatgtggtgctggtgaaggcgtcg
aactcggcgggattgggcgcgctcgccgagacggtcgcggccgacatcgctggcgacccg
ggtgcgcggcacccgggcccggtgcgggatgatgctccgcgatga
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