Mycolicibacterium gadium: MGAD_18230
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Entry
MGAD_18230 CDS
T07053
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mgad
Mycolicibacterium gadium
Pathway
mgad00290
Valine, leucine and isoleucine biosynthesis
mgad00660
C5-Branched dibasic acid metabolism
mgad01100
Metabolic pathways
mgad01110
Biosynthesis of secondary metabolites
mgad01210
2-Oxocarboxylic acid metabolism
mgad01230
Biosynthesis of amino acids
Module
mgad_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mgad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MGAD_18230 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MGAD_18230 (leuC)
Enzymes [BR:
mgad01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MGAD_18230 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MGAD_18230 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBZ17488
UniProt:
A0A7I7WNP6
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Position
complement(1804326..1805762)
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AA seq
478 aa
AA seq
DB search
MAAQDKPRTLAEKVWDDHVVAKGSGDGAAREPDLIYIDLHLVHEVTSPQAFDGLRLKGRP
VRRPDLTIATEDHNVPTIDIDKPIADPVSRIQVETLRRNCEEFGIRLHPMGDVEQGIVHI
IGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNV
DGQLPAGVSAKDIILAVIAKIGTGGGQGYVIEYRGSAIESLSMEGRMTVCNMSIEAGARA
GMVAPDETTFEFLHGRPHAPKGADWDAAVAAWSQLRTDEGAEFDTEVYIDAATLSPFVTW
GTNPGQGVPLSASVPDPELIFDDGERQAAEKALAYMDLRAGTSMRDITVDTVFVGSCTNG
RIEDLRVVADVLMGRKVADGVRMLIVPGSMRVRAQAESEGLGEIFAAAGAEWRQAGCSMC
LGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLTHS
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaggacaagccacgcacgctcgccgaaaaggtgtgggacgaccacgtcgtc
gcgaaggggtcgggtgacggcgcggcccgcgaacccgacctcatttacatcgacctacac
cttgtgcatgaggtcaccagcccgcaggcgttcgacggccttaggctcaagggtcggccg
gtccgcagaccggatctgacgattgccaccgaagaccacaacgtgccgacgatcgacatc
gacaagccgatcgccgatccggtctcccgcattcaggtcgagacgctgcgtcgcaactgt
gaagagttcggcatccggttgcacccgatgggtgacgtcgaacaaggcatcgttcacatc
atcgggccgcagttgggcttgactcagccggggatgacggtggtgtgtggcgacagccat
acctccacccacggtgcgttcggtgcgctcgcgatgggcatcggcacatccgaggtcgag
catgtcctcgcgacgcagacgcttccgctgcggcctttcaagacgatggcggtcaatgtc
gacgggcagctgcctgcgggcgtgagcgcaaaggacatcatcctcgcggtgatcgcaaag
atcggcaccggcgggggacagggatacgtcatcgaataccgcggcagcgccatcgaatcg
ctgtcgatggaaggacgcatgacggtctgcaacatgagcatcgaggccggggcgcgcgcc
ggaatggtcgcacccgacgagacaactttcgagttcttgcacggtcgcccgcacgcgccg
aagggggcggactgggatgccgcagtagcggcgtggagtcagttgcgcaccgacgaaggc
gcggaattcgacaccgaggtctacatcgatgccgcgacgctgagcccattcgtcacgtgg
gggaccaaccctgggcaaggagttccgctgtcggcgtcggtaccggacccagagctgatc
tttgacgacggcgagcgccaagcggccgaaaaagcgttggcgtatatggatcttcgggcc
ggaacgtcgatgcgtgacatcaccgtggacaccgtcttcgtgggctcgtgcacgaacggg
cgcatcgaggatctgcgggtggtcgccgacgtgctcatgggtcgcaaggtcgccgatggc
gtgcggatgctcattgtgcccggctcgatgcgggtgcgagcgcaggccgaatcagagggc
ctcggtgagatcttcgccgccgccggcgcggagtggcggcaggccggatgctcgatgtgt
cttggaatgaatccagatcaactgtccccggggcagcgctgcgcatcgacgtcgaaccga
aatttcgagggacggcagggcaaaggagggcgcactcatttggtgtcgcctgctgtcgcc
gcggccaccgctgtgcgcggcacgttgtcctctcccgccgatctgactcactcatag
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