KEGG   Mycolicibacterium gadium: MGAD_50620
Entry
MGAD_50620        CDS       T07053                                 
Symbol
bkdA
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
  KO
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
Organism
mgad  Mycolicibacterium gadium
Pathway
mgad00280  Valine, leucine and isoleucine degradation
mgad00640  Propanoate metabolism
mgad00785  Lipoic acid metabolism
mgad01100  Metabolic pathways
mgad01110  Biosynthesis of secondary metabolites
mgad01210  2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:mgad00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    MGAD_50620 (bkdA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    MGAD_50620 (bkdA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    MGAD_50620 (bkdA)
Enzymes [BR:mgad01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     MGAD_50620 (bkdA)
SSDB
Motif
Pfam: E1_dh Transket_pyr Transketolase_C Transketolase_N PFOR_II Transketolase_C_1 DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: BBZ20727
UniProt: A0A7I7WVH0
LinkDB
Position
5078074..5080095
AA seq 673 aa
MSAQTGTEASAPSTDLAVEFYRLMSKVQHGDKRVRKALSSGEAAMSYWPVDGQEAMSAGA
MLALADGDQLVTTYRGLGDVLAKGIDLEAYFAEILGRRDGLSKGKAGAMGICDPAHGIAW
TTGIVGAGPLIANGIALAAARRETGQVVLVSFGDGATSIGYVHEAMNMAAVWSLPVIFFC
QNNAWAEGTAYDRYTRAAQLSDRAVGYGMPGVTVDGTDPQAVYDAVSAAAERARAGAGPT
FVEAKAYRLQGHYFGDAMGYADQEELAAKRSDPPFVRYRARLIADGTATEAELDAIDNEV
TAELDAAFTAAAASEPPVVDELTRDVFSCNGSELAEPGQVHAVLPGGDTEEMGLVQAINR
TLDRAMAADESIVLLGEDIGDPSGGGMFKVTAGLSGKYGEGRVLDTPIAESAIVGAAIGA
SLGGLRPVAELMFMDFLGVAMDQIANHAAKVRYMSGGRKGAPLVIRTMVGMAAGPQHSQA
LEAWAMHTPGLKVVWPSTAADAAGLLKACLLDNDPCLFVESMKLYYGGGKGPVPVSDYVI
PLGQADVKRQGSDVTVVTYGVMVHAALEAAERLAGEGISVEVVDLRTLVPLDLATVLDSV
RKTTRLVVAHESVGFCGPGAEIAAAVGTELFGVLSAPIQRVAGTYTPIPRAATLEAACRP
GADQVVEAIRSIS
NT seq 2022 nt   +upstreamnt  +downstreamnt
atgtccgctcaaacaggcactgaggcctcggcgccgagcacagacctcgcggtcgagttc
taccgactgatgagcaaggtgcaacacggcgacaaacgagtgcgcaaggcgttgtcctcg
ggagaggcggcgatgagctactggccggtcgacggtcaggaggcgatgtcggcaggcgcg
atgcttgcgttggccgatggggaccagttggtcaccacctaccgcggactcggcgatgtc
ttggccaagggcatcgatctggaggcctacttcgccgagattctcggacgccgcgacgga
ttgtcgaagggcaaagcaggcgcgatgggtatctgcgaccccgcacacggcatcgcatgg
accaccggcatcgtcggtgcaggccccttgatcgccaacggcatcgcgttggccgctgcg
cgccgcgagaccgggcaggttgtcctggtgagctttggcgacggagccaccagcatcggc
tatgtccacgaggcgatgaacatggccgcggtctggtcactgccggtgatcttcttctgc
cagaacaacgcgtgggccgagggcaccgcttacgaccgatacacgcgcgccgcccagctg
tccgaccgcgccgtgggttacggaatgcccggggtcaccgtcgacggcactgatccacaa
gccgtctacgacgcggtttcggcggcggctgaacgagcgcgagccggagcgggcccgaca
ttcgtcgaggcaaaggcctaccggttacagggccactatttcggcgacgcgatgggatac
gcggaccaggaggaactggccgccaaacggtccgaccccccgttcgtccgataccgggcg
cggttgatcgccgatggaaccgctaccgaagcggaactcgatgccatcgacaacgaagtg
accgctgaactcgacgcagcctttactgccgctgctgcgtcggaacccccggttgtcgac
gaactcacccgagatgtgttctcctgcaacgggtcagagcttgctgaacccggccaggtg
catgccgtcctgccagggggggacaccgaggaaatgggtttggtgcaggcgatcaacagg
acacttgaccgagcgatggccgccgacgagtctattgttctgctcggcgaggacatcggc
gatccgtcgggcggtggcatgttcaaagtcaccgccggtctctcgggtaagtatggggaa
ggtcgcgtgctcgacaccccgatcgcggaatccgcgatcgtgggtgcggcgatcggagcc
tcgttgggcggcctgcgcccagttgccgagttgatgttcatggacttcctgggcgtcgcg
atggaccagattgccaaccacgcggcaaaggtgcgttacatgtccggcggtcgcaaaggc
gcgccgctggtgatcaggacgatggtgggaatggctgcaggaccgcaacattcgcaagcg
ctcgaagcctgggccatgcacacacctgggctgaaagtcgtctggccgagtaccgctgct
gacgccgccggactgctgaaagcctgtcttcttgacaacgatccgtgcctgttcgtggaa
tccatgaagctctactacgggggcggcaaggggcccgtgccggtttccgactacgtgatc
ccgctcggtcaggccgacgtcaaacgccagggatccgatgtcaccgtcgttacctatggc
gtcatggtgcatgcggctttggaggcggctgaaaggctggccggcgaggggatttcggtc
gaggtcgtagatttgcgcacgttggtaccgctggacctggcaacggttttggattcggtc
cgcaagacgactcgactggtggtcgcccacgaatcagtcggattctgtggcccgggcgcc
gagatcgccgccgcggttggtaccgaactcttcggtgtgctcagtgcgccgattcagcgc
gttgcagggacttacacgccgatcccacgggcggcgacgctggaagccgcctgccgaccg
ggcgcagaccaggtggtcgaggcgatcaggagtatttcgtga

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