Mycobacterium gallinarum: MGALJ_05800
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Entry
MGALJ_05800 CDS
T07342
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mgau
Mycobacterium gallinarum
Pathway
mgau00290
Valine, leucine and isoleucine biosynthesis
mgau00660
C5-Branched dibasic acid metabolism
mgau01100
Metabolic pathways
mgau01110
Biosynthesis of secondary metabolites
mgau01210
2-Oxocarboxylic acid metabolism
mgau01230
Biosynthesis of amino acids
Module
mgau_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mgau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MGALJ_05800 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MGALJ_05800 (leuC)
Enzymes [BR:
mgau01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MGALJ_05800 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MGALJ_05800 (leuC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBY90911
UniProt:
A0A9W4FDE1
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All DBs
Position
593485..594921
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AA seq
478 aa
AA seq
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MAAQDKPRTLAEKVWDDHVVAKGSGDGAAREPDLIYIDLHLVHEVTSPQAFDGLRLNGRP
VRRPDLTIATEDHNVPTIDIDKPIADPVSRIQVETLRRNCEEFGIRLHPMGDVEQGIVHI
IGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNV
DGQLPAGVSAKDIILAVIAKIGTGGGQGYVIEYRGSAIESLSMEGRMTVCNMSIEAGARA
GMVAPDETTFEFLHGRPHAPKGADWDAAVAAWSQLRTDEGAEFDTEVYIDAATLSPFVTW
GTNPGQGVPLSASVPDPELIFDDGERQAAEKALAYMDLRAGTSMRDITVDTVFVGSCTNG
RIEDLRVVADVLKGRKVADGVRMLIVPGSMRVRAQAESEGLGEIFAAAGAEWRQAGCSMC
LGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLTHA
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaggacaagccacgcacactcgccgaaaaggtgtgggacgaccacgtcgtc
gcgaagggatcgggtgacggcgcggcccgcgaacccgacctcatctacatcgacctgcac
cttgtgcacgaggtcaccagcccgcaggcgttcgacggcctccgcctcaacggtcggccg
gtccgcagacccgatctgacgatcgccaccgaagaccacaacgtgccgacgatcgacatc
gacaagccgatcgccgatccggtctcccgcattcaggtcgagacgctgcgccgcaactgt
gaagagttcggcatccggttgcacccgatgggtgacgtcgaacaaggcatcgttcacatc
atcgggccgcagttgggcttgactcagccggggatgacggtggtgtgtggcgacagccat
acctccacccacggtgcgttcggtgcgctcgcgatgggcatcggcacatccgaggtcgag
catgtcctcgcgacgcagacgcttccgctgcggcctttcaagacgatggcggtcaatgtc
gacgggcaactgcctgcgggcgtgagcgcaaaggacatcatcctcgcggtgatcgcgaag
atcggcaccggcgggggacagggatacgtcatcgaataccgcggcagcgccatcgaatcg
ctgtcgatggaagggcgcatgacggtctgcaacatgagcatcgaggccggggcgcgcgcc
ggaatggtcgcacccgacgagacaacgttcgagttcttgcatggtcgcccgcacgctccg
aagggggcggactgggatgccgcagtagcggcgtggagtcagttgcgcaccgacgaaggc
gcggaattcgacaccgaggtctacatcgatgccgcgacgctgagcccattcgtcacgtgg
gggaccaatcccgggcaaggagttccgctgtcggcgtcggtaccggaccccgagctgatc
tttgacgacggtgagcgccaggcggccgaaaaagcgttggcgtatatggatcttcgggct
ggaacgtcgatgcgtgacatcaccgtggacaccgtcttcgtcggctcgtgcacgaacggg
cgcatcgaggatctgcgggtggtcgccgacgtgctcaagggtcgcaaggtcgccgatggc
gtgcggatgctcattgtgcccggttcgatgcgggtgcgagcgcaggccgaatcagagggc
ctcggtgagatcttcgccgccgccggcgcggagtggcgccaggccggatgctcgatgtgt
cttggaatgaatccagatcaactgtccccggggcagcgctgcgcatcgacgtcgaaccga
aatttcgagggacggcagggcaaaggagggcgcacccatttggtgtcgcctgccgtcgcc
gcggccaccgctgtgcgcggcacgttgtcttctcccgccgatctgactcacgcatag
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