Mycolicibacterium gilvum PYR-GCK: Mflv_0486
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Entry
Mflv_0486 CDS
T00498
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
mgi
Mycolicibacterium gilvum PYR-GCK
Pathway
mgi00290
Valine, leucine and isoleucine biosynthesis
mgi00770
Pantothenate and CoA biosynthesis
mgi01100
Metabolic pathways
mgi01110
Biosynthesis of secondary metabolites
mgi01210
2-Oxocarboxylic acid metabolism
mgi01230
Biosynthesis of amino acids
Module
mgi_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mgi_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mgi00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mflv_0486
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Mflv_0486
Enzymes [BR:
mgi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
Mflv_0486
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ABP42979
UniProt:
A4T3P0
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All DBs
Position
510996..512765
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AA seq
589 aa
AA seq
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MWPMNRRAHNHPMPSDSRSHSLRASGSSVDIKPRSRDVTDGLERTAARGMLRAVGMTDDD
WVKPQIGVGSSWNEITPCNMSLQRLAQAVKGGVHEAGGYPLEFGTISVSDGISMGHEGMH
FSLVSREVIADSVETVVQAERLDGTVLLAGCDKSIPGMLMAAARLDLASVFFYNGSIMPG
VAKLTDGSEKEVTIIDAFEAVGACARGLMSREDVDIIERAICPGEGACGGMYTANTMASA
AEALGMSLPGSASPVAIDKRRDDFARRSGEAVVEMLRRGITARDILTKEAFENAIAVVMA
FGGSTNAVLHLLAIAWEAQVELTLADFTRIGQKVPHLADVKPFGAYVMKHVDEIGGVPVV
MRALLDAGLLHGDCLTVTGQTMAENLAHIEPPDPDGKVLRAMNNPIHPTGGITILHGSLA
PEGAVVKSAGFDSDVFEGTARVFERERAALDALEDGTITHGDVVVIRYEGPKGGPGMREM
LAITGAIKGAGLGKDVLLMTDGRFSGGTTGLCVGHIAPEAVDGGPIAFVRDGDRIRLDVA
NGTLDILVDEAEFESRKAGFEPLPPVYTTGVLAKYTKLVGSAAVGAVCS
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtggccgatgaatcgacgggcgcataatcaccccatgccctcagactcacgctcgcat
tctcttcgcgcaagcggctcatcggtcgacatcaaaccccgcagccgcgacgtgaccgac
gggctcgagcgcaccgccgcgcgcggcatgctgcgcgcggtcggcatgaccgacgacgac
tgggtcaagccccagatcggggtcggctcgtcgtggaacgagatcacgccgtgcaacatg
tcgctgcagcggctggcccaggcggtcaagggcggtgtgcacgaggccgggggttacccg
ctggagttcggcacgatctccgtctccgacggcatctcgatgggccacgagggcatgcac
ttctcgctggtgtcccgcgaggtcatcgccgacagcgtcgagaccgtggtgcaggccgaa
cgcctcgacggcacggtgttgctggccggctgcgacaagtcgatccccggcatgctgatg
gccgcggcccgcctcgatctggcgagcgtgttcttctacaacggctcgatcatgccgggc
gtcgcgaagctcaccgacggaagcgagaaggaagtcacgatcatcgacgccttcgaggcg
gtcggtgcgtgtgcgcgcgggctgatgtcgcgggaggacgtcgacatcatcgagcgggcc
atctgccccggtgagggcgcctgcggtggcatgtacaccgccaacacgatggcctcggcc
gccgaggcgctcggcatgtcgctgccgggcagcgcgtctccggtggcgatcgacaagcgg
cgcgacgactttgcgcgccgctccggcgaggcggtggtcgagatgctgcgtcgcggcatc
accgcccgcgacatcctgaccaaggaggccttcgagaacgcgatcgccgtcgtgatggcc
ttcggcggttccaccaacgcggtgctgcatctgctggccatcgcgtgggaggcgcaggtc
gagctgacgctggcggacttcacccggatcgggcagaaggtgccgcacctggcggatgtg
aagccgttcggcgcgtacgtgatgaagcacgtcgacgagatcggcggcgtgccggtggtg
atgcgggcactgctcgacgccggactgctgcacggggactgcctcacggtgaccggtcag
acgatggccgagaacctggcccacatcgagccgccggaccccgacggcaaggtgctgcgg
gcgatgaacaacccgatccacccgaccggcggcatcacgatcctgcacggatcgctggcc
cccgagggcgcggtggtcaagtcggccggcttcgactccgacgtgttcgagggcaccgca
cgggttttcgagcgcgaacgggcggcgctcgacgcgctggaggacggcacgatcacccac
ggcgacgtcgtcgtcatccgttacgagggccccaagggcggcccggggatgcgcgagatg
ctggcgatcaccggtgcgatcaagggcgccgggctgggcaaggacgtgctgctgatgacc
gacggacggttctcgggcgggacgacgggtctgtgcgtcgggcacatcgcgccggaggcc
gtcgacggcggaccgatcgcattcgtgcgtgacggggacaggatccggttggacgtcgcc
aacggcacgctggacatcctcgtcgacgaggccgagttcgaatcgcgcaaggcgggcttc
gaaccgctgccgccggtctacacgacgggggtgctcgccaagtacacgaagctggtgggt
tcggcggcggtcggcgcggtctgcagttag
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