Mycolicibacterium gilvum PYR-GCK: Mflv_2984
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Entry
Mflv_2984 CDS
T00498
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mgi
Mycolicibacterium gilvum PYR-GCK
Pathway
mgi00300
Lysine biosynthesis
mgi00550
Peptidoglycan biosynthesis
mgi01100
Metabolic pathways
mgi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mgi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mflv_2984
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mflv_2984
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mflv_2984
Enzymes [BR:
mgi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mflv_2984
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABP45461
UniProt:
A4TBF1
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All DBs
Position
3155269..3156783
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AA seq
504 aa
AA seq
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MIEMSLRRIAEIVGGRLADVSADEADRLRVTGTVEFDSRAVTAGGLFLALPGARSDGHDF
AATAVASGAVAVLAARPVGVPAVVVDPVAPQHGAGGTAGVLEHDADGSGAAVLAALARLA
AAVAAELVAGGLTIVGITGSSGKTSTKDLIAAVLAPLGEVIAPPGSFNNELGHPWTVLRA
TESTDYLVLEMSARHPGNIAALARIAPPSIGAVLNVGTAHLGEFGSREAIAATKSELPQA
VPQSGVVILNADDPVVAAMADKTAARVVRVGRSADARTLDVRADGVTLDPLARPAFTLHA
GGEQVPVTLAVHGDHQVSNALVAAAVALECGATLTQVAGALAAAGPVSRHRMQVSTRSDG
VTVINDAYNANPDSMTAGLKALAWMSRQNPEGSRSFAVLGEMAELGEDTITEHDRIGRLA
VRLDVSRLVVVGSGRPMSAMLHGAVMEGSWGSEATPVADADAALALLRDELRPGDVVLVK
ASNSAGLGALADALVSEQLPGDGR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagatgtcgttgcgccggatcgccgagatcgtcggcggccggctggccgatgtg
agcgccgacgaggcggaccgcctgcgggtcaccggcaccgtcgagttcgactcgcgcgcg
gtgaccgccggtgggctgttcctggcgctgccgggggcgcgctcggacggccatgatttc
gccgccacggccgtggcgtccggtgcggtcgcggtactggccgcccggcccgtcggggtg
ccggcggtcgtcgtcgacccggtggccccgcagcacggcgcgggcggcaccgccggggtg
ctcgagcacgacgccgacggttccggcgcggcggtgctggcggcgctggccaggctggcg
gccgcggtcgccgccgaactcgtcgcgggcggcctgacgatcgtcgggatcaccggctcg
tcgggcaagacctcgacgaaggatctgatcgccgcggttctcgcaccgctcggagaggtg
atcgcgccgccgggatcgttcaacaacgaactcgggcacccctggacggtgctgcgggcc
accgagtccaccgactacctggtgctggagatgtcggcgcgccaccccggcaacatcgcg
gcgctggcccgtatcgcgccgccgtcgatcggcgcggtgctcaacgtcggcaccgcccac
ctcggcgagttcggctcccgcgaggccatcgccgcgacgaagtcggaactgccgcaagcg
gttccgcagtccggtgtggtgatcctcaacgccgacgatccggtggtcgcggcgatggcg
gacaagaccgccgcgcgggtggtgcgggtcgggcggagcgccgacgcccgcacgctcgac
gtgcgcgccgacggcgtcaccctcgacccgttggcgcggcccgcgttcacgctgcacgcg
ggcggggagcaggtgcccgtcaccctcgcggtacacggggaccatcaggtgtccaacgcg
ctcgtcgcggccgccgtcgcgctggagtgcggcgcgaccctgacgcaggtggccggggcg
ctcgcggcggccggcccggtgtcgcggcaccggatgcaggtcagcacccgcagcgacggc
gtgaccgtgatcaacgacgcctacaacgccaaccccgactcgatgaccgcagggctcaag
gcgctggcgtggatgagtcggcagaaccccgaaggcagccgcagcttcgccgtgctcggc
gagatggcggaactcggtgaggacacgattaccgagcatgaccgcatcggccgcttggcg
gtgcgcttagatgtctctcgactcgtcgtcgtcggatccgggaggcctatgagcgccatg
ctgcacggcgcggtgatggaagggtcgtggggatccgaggccacgcccgtcgccgacgcc
gacgccgcgctggcgctgttgcgggacgaactgcgtcccggcgacgtcgtgctggtgaag
gcctccaactccgccgggctcggcgccctggccgacgcgctggtgtccgaacagctcccg
ggggacggccgatga
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