Meleagris gallopavo (turkey): 100542938 Help Entry 100542938         CDS       T01523                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism mgp  Meleagris gallopavo (turkey) Pathway mgp04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mgp00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100542938 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mgp03036]     100542938 (SYNE1) Chromosome and associated proteins [BR:mgp03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100542938 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Motif Other DBs NCBI-GeneID:  100542938 NCBI-ProteinID:  XP_010705495 LinkDB All DBs Position 2:complement(48045039..48331507) Genome browser AA seq 8806 aa AA seqDB search MASSRLVTRSRDIANVMQRLQDEQELVQKRTFTKWINTHLAKRNPPMMVSDLFEDIKDGV MLIALLEVLSGQKLPCEQGRHLKRIHWVANIGTALKFLEGRRIKLVNINSTDIADGRPSI VLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSKRKVVTKVQGSAR KALLKWIQYTAARQVGIEIKDFGQSWRSGVAFHSIIHAIRPDLVDMEKVKGRSNRENLEE AFTLAETELGIPRLLDPEDVNVDKPDEKSIMTYVAQFLKYYPDPHHTVADVQENDKEDKL MLRDLKVWAEQFERDLARAQVAETSLQEKYQSFKHFRIQYEMKRKPIELVTQSLRKDGKL SLDQAIVKQAWDRVSSRLFDWHIHLDKSLPAPLGTIGAWLYRAETALREEVSIQQAHEET ANIIHRKLEQLKDLLKNIEGHKKTFHEIHGARSVNGVPVPPDQLEDMAERFNFVVSSSEL HLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRDSVELLLQNYISVIENSKFFEQYEV TYQILKRAAEMYAKANGSVEEVESVMKFMSETTAQWRNLSVEVRSVRSMLEEVIANWDRY SSTVAGLQAWLEDAEKMLNQTEQSKKDFFRHLPHWIQQHTAMNDAGNFLIETCDETISRD LKQQLLLLNGRWRELFMQVKQYARADELDKMQKEYLDGVANLTAFIDGSNRKFSAPTEVS FLDVKIFVQDLENIKQKLPAMEAQYKMVARTAQLVTKEVSQEEVNEMLATLTKIKEQLSK VKENSCALLYECQHLLSPLEEQEKQITNFYESLEKVNEIISILDPEAQPTTVLKQKAQDL VAYQENCKKALSLIERNSQSILQCVASSEVLKHFHHSTFQKKVTQVQITFQNMVRKAGDW RKNIEVNSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEFFNQLDQRVLNAF LKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQMEAPYHLIHLKIEVQKSKLLVTVEEC KAELARQNKALTREGKERMIEEHKLFFGDKGSYHLCEKRLQRIEELCHKLPVSDPVRATL ESSQRILKELKSQIDSTYTKLTEHSDIWKSYTNRFSELANWISSTERELKRIKESVNDTA KYEQFKSSVGEIRQHINKEGENHSWLKSRLAVITKICTDVEAKKTEDELCKLSSDFKGLL DLLAEIERTLGTVGDCVQYKEEVKTAIEELINNSKEAQAEAEKILDTESLLQAQQLLFHH QQRTRRLRAKRQGVQQQIFQAKQLQIEGGLPSAMQEDLLKLEGTLENMQQTMEKREEQLQ VTINKWEQFERDKETVVKYLNQASCALERILNFSSLESLSSELDQTKELSKHSEAMAVQA ENLVKNSSEIQLGSKSKHALQQQAKSIQEQVKKVDVTLEEDLKRMEMMKNKWDHFGKNFE ALSTWIAEKEKELETLETPSSPLDTQISQIKVINTEIDGKINGISKLEEEAKSFTQFVTS GECAHIKAKLTHIKRYWEDLREHAQRLEGTITGKASAQKIYEESLKQVQQSVSEFETKLA EPLTSCTSSSATYGDLQDCTDLCHTVEKLSNTLASLSACARKAASKEKAAQEVTALQQRY EKVLENAKEKQMLLETLLVRWQKQEKELCAFQIWLEGCEAAARPSEQYVSADRVKLEGEL QSLQDLRADFESHASVYASLLQLNESLFPTASKQCVKAIKEKCKELDERWKALPQTIDKR INFLQSLVAEHGQFDELLCGFSDWIKQFLAQLQSTSEINTADQELAASHNKNHSMEIESK KQQLQNLKDLVNKLCVFSCPEDQQILQGKTEDCFQIFQEANQITKQRQEALDQLQVFLEL HNAASRVLHQLRQTVEKTGNMDKAKSELLEKDLHDVIQSLNKLESIAISLDGSLTKAQYH LKHGISEQRTSCRAVVDHLYLELEAVQNLLGTKQSEAEALATLRKSFMERKEELLKSIED TEEKADKEGLREATLQALQQRLRIFNQLDEDLNSHQHELQWLMDKAKQIAQKDITLAPEI DKEINHLASLWEDTKKVIQEKKEQSCILIDLIKEYHSLKSTVMKVIDSADSASVIKSIWK DREDFRRTLSKHEAAKNDLSDKQKDLDTFTNKGKHLLAELKKVHNCECTVVKMDMDSTVD KWLDVSERIEDNIHRLNLGVSLWDDILKIADEMDGWCTNCISHLNEGISNLSNSLRMEVI LKDFQSQVKDKEQKLEQLNSKISELKELTHSQEPPADLQFIESDLRQKLEHAKEMSQTAK ETLKDFNTQKMQLQKFIDKMTHWLTETEETLLRCSRNLDPEALNLVKETQKDLQLQQSSI DSTRENLNRLCRKYHSVELETLGGTVTSLLKKYEAVNQLCSRTQANMQECLEKHFLYSMQ EFQEWFSDVKAAVKELSDRSGDSKAIEAKLHDLQSVLDSLSEGQNKLDAACKEGENLYTC LPQPVVIHIQEQVAKTNQNFKEFLSQCLNDKQALEACASYLGSFEEQHKKLSLWIHDMEE RMSTEALGEIKELIPEKKKEVQKVEKFLEELLASRESCEKLAQIAQALNEEGHGAGREVR LASQHLTNYQNMVKTVKEKLQTCQLALQEHLTLEEALQSMWSWVKEVQEKLASAESTVGS KATLEQRLTQIQEILLLKGDGEVKLNMAIGKGEQALRSSNEEGQKMIQIELQRLKDVWND IISTSMSWQSCLESLISQWNEYLERKSQMEQWLEKLDHKVEQPLEPQLGLKEKFAQLDYF QAIVSEIEDHSGDLQQLVEKTAELYKKTEDDSFGAAAQEELKTQFNDITTVAKEKMKKVE DIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDATGDTSVIQKKLAKINELVDSRQIGAGR LGRVETLAPAAKRSTSAGGCQLLAAEMQALQLDWKQWEESAFQSQRSLRDMLSQMAVSEQ EFATQVARLEEAVQRFGGLLAAWSQSLTPLDSRHTDTEIVESWRKEKETSDALIKSEHAI DEIKTQLNDLCRFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTSFRDF QQWLVNAKVTTAKCFDVPQDISEASASLQKVQEFLSESENGQHKLNLVASKGELLCSILP KEKAKVISDKCAMVKEDWKNFISTLHQRESALENLKIQMKDFEATAEPLTEWLSTTEKIV QGSSSRLHDLPSKRREQQKLQSVLEEISCHEHQLNRLKEKAQQLLEEQAVSKSFMRRVSQ LSSQYLTLSNLTKEKVSKMDRVVGEHQQFSHDFKDLQDWVADAIHMLESYCHPTADKNVL DSRMLKLEGLLTLKQEKEIQMKIILTRGESVLQNTSPEGVQVIEQQLHTLKDSWASLLSA CIRCKSQLEGALSKWTSYQDDVRQFTSWMDKVEASMNSSQRQYAELREKTAALSKAKLLS EEVLSHSSLLETIEVKGSGMAEHYVTQLELQELQERYKLLKDRTREAVKKAEELLNLHQG YQRNLKAFETWLEEEQEKLSCLSHLEGDAQKQEATLRDLQELQVHCAEGQALLNAAVRAR EEVIPWGVPQIEDRALESIRQDWQVYQHNLSEARSQLNAAVSRLRLMEKKFQKVNDWITE LEEKVAIRTGRQSGRATKEMQLQQMKKWHEEITIYKDDVEEVGILAQQILEEGLTTSGMG SQATQLTSRYQTLLLRILEQTKFLEEEIRSMEESELAFSAYKNWYGATNKDFRNVITKFD VLNKTAMEKKVQKLELLLSDMDIGHSLLKSAREKGERAIKYMEENGVDGLRKEIGDHVEQ LEDLAGSIRKEHVTSEKCLQLAKEFSDKYRAQTQWLTEYQAMLHTPVEPKCELYEKKAQL SKYKSIQQTILSHESSIKSVIEKGEALFDLVNDMTLKNNIQDLQSNYHELCSATKACVET LEVRVKEHEDYNSDLQEGEKWLLHMSSRLVSPDLMESNSLEIITQQLANHKAIMEEIAGF EDCLDKLKSKGDYLISQCTEHLQAKFKQNIQSHLQGTRDSYSAICSTAQRVYQSLEHELQ KHVNHQDTLQQCQTWLSTVQSELKPSTWAPFSQADAVKQVKHFRALQEQANTYLDLLCSM CDLSDATVKSTATDIQQKKQMIEQQIMHSQYLAQGWEEIKQMKAELWIYFQDADQQLQNL KRRRAELELNIAQNMVLQIKEFSQKLQCKQSALTSVTEKINKLTQGQESPEHKEIGQLSN QWLDLCLQAHSLLIQREEDLQRTVDYHDRMHIVEVFLEKLTKEWDNLARSDAESTNVHLE ALQKLALTLQERRFALEDLKDQKQKMVEHLNLDDKELVKEQFGHFEQRWTQLEELVKRKI QISVSTLEELSLVHSKLQELMEWAEEQQPSISEALKHSPPPDLAQSLLMDHLTISSELEA KQLVLKTLLKDAERVMTSLGLNERQELQKALSDAQHHVDCLSDLVGQRKKHLNKALSEKT QFLMAVFQATNQIHQHEKKVTFPEHICLLPEDVNKQIRTCKSAQASLKAYQNEVTGLWAQ GRDLMKEATEQEKSEVLGKLQELQNIYDTVLQKCTQRLLELEKNIVSRKYFKEDLDKACH WLKQADIVTFPEVNVMNSNSELYTQLSKYQQILEQSPEYENLLLTLQRHGQEILPSLNEV DHSYLDEKLNILPQQFNTVSALAKDKFYKVQEAIYARKEYTSLIELTTKALTELDDQFIS MDKAPAAVLAKEALALQQAYKDLLDEVMSLGAAVDELNQKKEAFRSTGQPWQPDEMLKLV TLYHKLKRQIEQKINLLEDTVEVCQEHEKMCTQLEAQLEAVKNEQIKVNEEMLPIEEKLK IYHSLVGSLQDSGSLLKRITEHIETLSPQLDPSARETTNHQVLLWQDKLKNLHAAIGDIV MDCENRLVQSIDFQTEICRSLDWLRWVKTELSGKLSLDLKLQSIQEEIRKVQIHQEEVQS SLRVMNALSNKEKERYMKAKELIPADLENTLAELTELDGEVQEAIRIRQATLDKLYSLCR RYYQVIQITNDWLEDAQEFLHLTRNGLDVENSEGNLGNHIEFFSTESQFSNNLKELQGMV PELEPFIHATAREQLMQNLALLEEKGKGTKQEANNQQELLQRCASKWQEYQTARQKVIEV MNEAEKKLSDFSVAKASSSHEAEEKLQTHKTLVSVVNSFHEKITTLEEKVSQLEEVSSDT SKATVSRSMTTVWQRWTRLRNVAQEQEKILEDAVQEWNGFNDKIQKATVVIDQLQDRLPE SSVEKASKTELLELLDYHSSFLLEVEHQLSSLGLLKQHALNMLQDVEIKPLFQEEVPVMQ EVKAMQDRCHNMQQKVKNSVKLVKQELKDREEVEAQINVVKTWIQETKEYLLSPNVELDT QLQELKSLFCEVTTHRQAVEKMAEQQQNKYLGLYTILPSELSLHLAEVGLALVTVQDQIQ DKEKETGHIKALNQEFEQQIQEIANELNAILSKLKRKTDDIVQAKLEQKILGEELDSCNI KILELDASVQEFSEQNIPLAKQLANRIGKLTALHQQTIRQAEYRATKLSQATSHLEEYNE MLEFILKWIEKANILVRGSITWNSSSQLRDQFKAYQTMLEESGEIHGDLEAMSERIECLA SVYSTEGMSQQVLELGRRTEELQQIIKVRLPNLQDAAKDMKKFEVELRALQAALEQAQAT LTSPELGRLSLKEQLSHRQHLLSEMESLKPKVHAVQVCQSALRIPEEVVTSLPICHSALQ LQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQDKPVATSNIQEL QNQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLSEGVEELDSD LLPAHPAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQ DIAYYQALSAEQLQTEAAKIQPSTSATQEFYEPGLESAASAKLDDLQRSWETLKNVISEK QRTLYEALERQQKYQDTLQSISTKMETTEMKLNESLEPAKSPESQMAEHQALMDEILMLQ EEITELQTSLAQELVSESLDAEAADQLALQSTLTVLAERMATIRMKASGKRQLLEEKLSE QLEEQRQEQALQRYRCEADELDHWLLNTRATLDTALVTAEEPMDMEAQLVDCQNMLVEIE QKVVALSELSVHNENLLMEGKAHTKDEAEQLALKLRTLKGSLLELQKVLHDKQINIQQGS LQEKEESNLDLVSSQSPSVQEWLAQARTTRSQQQQSTLQQQKELEQELEEQKNLLRSVAC RGEEILTQQGTPEGLRISEKPEKLSEELCLEGEKSSPEQQLKIKWESLNHKFSTKQKLLQ KTLEQEQLQIYSRPNRLISGLPLYKENGQDEEKSSVSPVLVELNQAFEDASSETGHVEKE SLHLEQKLYDGVASTSLWLDGVEEQVFVATALLPEEETETYLCKQESLAKEIKDITEEMD KNKNLFTQIFPENGDNREVIEDTLDCLLRRLTLLESVVNQRSHQMKERLQEIMTFKNDLK LLYTSLADSKYLVLQKLAEAVEKPETEQIQVIMQAEESLKELDAGISELKKSVDKLQIDQ PSVQELCKLQDMYDEVMMIIGSRRSDLNQNLALKRQYERALQDLADLVETGQEKMDGDQK MIVASKEEVQSLLNKHKEYFQGLESHMILTETLSRKMSSFALLKEIQSHPELMTQASTVL KLAHKRGVELEYILETWIHLDEDYQELTRQLESVEGSIPAVGLVEETEDKLIERIKLFQH LRSNLTEYQPKLYQVLDDGKRLLFSVSCSDLESQLNQLGEHWLSNTSKVNKELHRLETIL KHWTRYQSESIELTHWLQSAKERLEFWSQQSLTVPQELETVRDHLNSFLEFSKEVDAKSS QKSSVLSTGNQLLRLKKVDTAALRAGLSHIDSQWTELLTHIPIVQEKLHQLQMDKIPSRH AITEVMSWISLMENVIHKDEESIKNIIGQKAIQDYVQKYKGFKIDLNCKQLTIDFVNQSV LQISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLVTEKIQLLESLQESWTEYENNVQCL KSWFETQEKKLKKQQRIGDQASVQNALKDCQELEESIRTKEKELESIEKSGLSLIQNKKE EASSAVLNTLQEINHSWASLDHVVSQLKILLQSVLDQWSIYKVTYEELNSYLMEARYSLS RFYLLTGSLEAVKVQVNNLQSLQDELEKQENSLQKFGSVTNQLLKECHPPVTETLTNTLK EVNMRWNNLMQEIAERLRSSKGLLQLWQRYKDCYQQCSSTVRLREDQTNELLKTATSKDI ADDEVTTWIQDCNDLLADIKTAQDSLIVLQELGEELKSRVEASAAAAIQSDQLSLNQNLS ALEQALCKQQTVLQAGVLDYQTFAKKLQDLEAWVTEAEAKLKGQDPGHASDLSAIQSRME ELKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRIQNLNRQWSLISSQTTERFSKLQSF LLQQQTFLEKCETWMDLLVQTEQKLAAEISGNYQSLLEQQKAHELFQAEMFSRQQILHSI ISDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIHQWQRYREMAEK LRKWLVETSCQPVSGLGNAPIPLQQARALLDEVQLKEKVLLRQQGSYILTVEAGKQLLLS ADSGAEAALQAELTEIQERWKKVSTQLEEQKKQVTLLLKDWERSEKGIADSLEKLRSFKK KLSQPLPEHHDELNAEQIRCKELENAVDGWTDDLAHLSLLKESLSTYISADDISVLSERI ELLHRQWEELCHQVSLRRQQVSEKLNEWAVFSEKNKELCEWLTQMESKVSQNGDIVIEEM IEKLRKDYQEEIAVAQESKIQLQQMGERLAKASHESKASEIEYKLGKINDRWQHLLDLIA ARVKKLKETLIAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEIQRKLNEQQELQR DIEKHSTGVASVLNLCEVLLHDCDACATETECDSIQQATRNLDRRWRNICAMSMERRLKI EETWRLWQKFLDDYSRFEDWLKNSERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLT QLELINKQYRRLARENRTDSDCSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFE TARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNKIHQIIVQGEQLI EKSEPMDAAVIEEELDELRRYCQEVFGRVERYHKKLIHLPLTDDEHDLSDKEVDLDESAD LSDIHWHEKSADSVLSPHPSSNLSLPLAQPVRSERSGRDTPASVDSIPLEWDHDYDLSRD LETAVSRALHSEEEDGEQEKDFYLRGATSIADVEIPETLEAYVTLTENALKNISGEPGAL EAHIRQLDKALDTSRFQIQQTENIIRSKTPTGPELDATYKGYMKLLGECSGSIDSVKRLG YKLKEEEEKLSGLINLNSTETQTAGVIDRWELIQAQALSKELRMKQNLQQWQQFNSDLNS IWAWLGETEEELEKLRRLDLSTDIQTIELRIRKLKELQKAIDNRKAIILSINLCSSEFTQ SDSEESKKLQERLSQMNICWDHVCSMIEEWRCSLQDALMQCQDFHEMSHGLLLWLENIDR RKNEIVPINPNLDSEILQDHHRLLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDCLEA KEKVHVIGNRLKLLLKEVIRHIKDLEKALDISSSQLDLSSWSSADELDTSGSVSPVSGQS TPSRQRTPRGKCSLSQPGPSVSSPHSRSIRDGSGSSPSEAGPAWQHPSFFLRVLRAALPL QLLLLLLIGLACLVPMTEEDYSCTMANNFARSFHPMLKYMNGPPPL NT seq 26421 nt NT seq  +upstreamnt  +downstreamnt atggcctcatcccgactcgtgacaagatctagggacattgctaatgtcatgcaacggctt caagatgagcaagaattggtacaaaagaggacttttacaaaatggatcaatactcatctg gctaagcgcaatcctcccatgatggtcagtgatttgtttgaagacatcaaggatggggta atgctgatagcccttttggaggttctctcagggcagaagctgccttgtgagcaaggacgt catctgaagagaattcactgggttgccaacattggcacagcacttaagtttctagaagga agacggataaagcttgtcaacataaactcaactgatattgctgatggtcggccttctatt gtgcttggcttggtgtggaccataattttatattttcagattgaagagctcaccagcaat cttccacagttgcagtcattgtctagcagtgcgtcttctgtagagagtgttgtcagttca gaaactgcaagtcccccaagcaaacggaaggtggtaaccaaggtccaaggaagtgccagg aaggctttgttaaaatggatccagtatacagcagcaaggcaagttggaattgaaatcaaa gactttggacaaagttggaggagcggtgttgcatttcattccattattcatgctatccgt ccagatttagtggacatggagaaagtaaaaggaagatcaaacagggaaaacctggaagaa gccttcacactcgcagaaacagagctagggattccgaggctccttgatccagaagatgtg aatgttgacaagccagatgaaaagtctatcatgacctatgtagcccagtttttgaagtac tatcctgatcctcatcatacagtggctgatgtgcaggagaatgacaaggaagacaagttg atgctgagagacctaaaagtgtgggcagaacagtttgaaagagatttagcacgggcacag gtggcagaaacaagcttacaggagaaatatcagtcatttaagcacttcagaatccagtat gagatgaaaaggaaacctattgaacttgtaacccagtccttaaggaaagatggtaaatta tcacttgatcaagctatagtgaagcaagcgtgggacagagtttcttccaggctgtttgac tggcacatacatcttgataaatctcttcctgcacctttgggtaccataggtgcttggctc tatagagcagagactgctctaagagaagaagtaagcattcagcaagctcatgaggagaca gcaaatattatacaccggaagcttgaacagcttaaggatctattgaaaaacatagaaggt cacaaaaagacattccatgagatccacggggcaaggtctgttaatggagtgcctgttcca cctgaccaattagaggatatggcagagaggtttaattttgttgtctcttcatctgagctc catctgttgaaaatggagttcctggaactgaagtaccgtctactgtcactcttagtcctt gcagaatcaaagttaaaatcatggattattaaatacggaagaagagactcagtggaacta cttctgcaaaattacatatctgttattgaaaatagtaagttctttgagcaatatgaagtt acataccagatcttgaaaagagcagctgaaatgtatgccaaagcaaatgggtcagtggaa gaagttgagagcgtgatgaaattcatgagtgaaacaacagcgcagtggaggaacctctcg gtagaggtgagaagtgtaagaagcatgttggaagaagtaattgctaactgggacaggtac agcagcactgtggcaggtctgcaagcctggttggaggatgctgaaaaaatgcttaatcag actgaacagtctaaaaaggatttcttccggcacttaccccattggatccaacagcacaca gccatgaatgatgctggtaattttctgattgaaacatgtgatgagaccatttccagggac cttaagcagcaacttctgttactaaatggaagatggagagaattgtttatgcaagtgaag caatatgctcgggcagatgaattggacaaaatgcaaaaagaatacctggacggtgtggct aatttgactgctttcattgatggaagcaatagaaaattttcagcacccacagaagtgtcc ttcttagatgtgaagatctttgtacaagatttagaaaatattaagcagaaattgcctgcc atggaagctcagtacaaaatggtcgcgagaacagcacagctggttacaaaagaagtttcc caagaagaagtaaatgaaatgcttgcaactttgacaaagatcaaagagcagctgagcaag gtcaaggagaattcctgtgccctactgtatgaatgccagcatctgctgtctccgcttgaa gaacaggagaaacaaatcacaaatttctatgaatctcttgaaaaggtcaatgaaataatt tctatcctggatcctgaagcacagcctacaactgttcttaagcaaaaagctcaagatttg gtagcttatcaagaaaactgcaagaaagctttgtccctcattgagagaaatagtcagagt atcctgcagtgtgtggcttctagtgaagtgttaaagcatttccatcactcaacatttcag aagaaagttacacaagttcagattacttttcagaatatggtcaggaaagctggtgactgg aggaaaaacatagaagtaaatagccgtttgatgaagaaatttgaggagtctagagcagaa ctggagaaagtgatacagattgccaattgttgcttaaaagaaaaaggaaatcctgaagag cttctcagaaagcatagcgaattttttaaccagttggaccagagagtcctaaatgccttc ctgaaagcttgtgatgaacttactgacatccttcctgaacaagagcaacacagcctgcag gaagctgtgagaaaactccataggcagtggaaggatcttcaaatggaagccccgtatcac ttgatccatttgaagattgaagtgcagaaaagcaagctcctggtaacagtggaggagtgc aaagctgaactagctcgacagaataaggcgctcaccagagaaggcaaagaaaggatgatt gaagagcacaagttattctttggtgacaagggatcttaccatctctgtgagaaaagatta caacggattgaagaactgtgccataaacttccagtttctgatccagtgagggctacgttg gaaagtagccaacgaatcctgaaggagctcaaatctcagatagacagtacatacacaaaa ctaacagagcattcagacatctggaagagctatacaaacagattttctgaattggcaaat tggatttcatctacagaaagagagctaaagaggataaaggaaagtgtcaatgatactgct aaatatgagcaatttaaatcatctgttggggaaatcaggcagcatattaacaaggaggga gaaaatcacagctggctgaaatccagacttgcagttattactaaaatatgtacagatgtg gaggccaagaaaacagaagatgagctttgtaaactttccagtgacttcaaaggacttctg gatttgctagctgagattgaaaggacattaggcactgttggagattgtgtccagtataaa gaggaggttaaaactgcaatcgaagagttaatcaacaactctaaggaagcccaagcagaa gctgagaagatcctggatacggaaagtttattgcaagctcagcaactactgtttcatcat cagcaaaggacaaggagactccgtgcaaagagacaaggtgtgcaacagcagattttccaa gctaaacagttacagattgaaggtggactgccaagtgcaatgcaggaagatttactaaag ctagaaggaacactggagaacatgcagcagactatggagaaacgtgaagagcaactgcaa gtcacaataaataaatgggagcagtttgaaagagacaaagaaacagtagtaaaatatctt aatcaagcaagctgtgcacttgaacgtatcttaaactttagcagtttagagagcctctct tcagaactggatcagacaaaggagctttctaaacacagtgaagccatggcagtacaagct gaaaacttggtgaagaattcttctgagatacagcttggttcaaagagcaaacatgccctg cagcagcaggcaaaatctatccaagaacaagtgaaaaaagtggatgttactctagaagaa gatcttaaaagaatggaaatgatgaaaaacaagtgggatcattttggcaaaaattttgaa gctctgtccacctggatagctgaaaaagaaaaagaactggaaactttggaaacaccctca tctcctttggacacacagatcagccaaatcaaggttattaatacagaaatagacggtaaa ataaatggaatctcaaaactagaagaagaagccaaatcatttacccagtttgttacttct ggagaatgcgcacatattaaagccaaactgactcatatcaaaaggtattgggaagatcta 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cctgagctggagccctttatacatgccacagcaagagagcagctcatgcagaatctagct ttgttggaagaaaagggcaaagggacaaagcaggaagccaataatcagcaagaactgttg caaaggtgtgcttctaagtggcaggagtatcagacagcacgacaaaaggtcattgaagtg atgaatgaggctgagaaaaaattatctgatttctcagtagctaaagcttcttcttctcat gaagcagaagaaaaattgcaaacacataagactcttgtgtctgtagtaaattctttccat gaaaagatcacaactcttgaagaaaaggtttcacagctggaagaagttagcagtgatacc agcaaggcaactgtaagtagatcaatgacaacagtttggcagcgctggacacgactccgg aatgtagcccaagaacaagagaaaattttggaagatgcagtacaggaatggaatgggttt aatgataagattcagaaagctactgtagtgatagatcaactacaagatcgtttaccagaa agctccgtagaaaaagcatctaaaacagagctcctggaactcctggattaccacagcagc ttccttctggaagtggagcaccagctatcatctttgggtctgctcaaacagcacgctctt aatatgcttcaggatgtggaaataaagcctctgtttcaggaagaagtaccagtcatgcaa gaagtcaaagcaatgcaagatcgatgccacaatatgcaacagaaagtgaaaaatagtgta aagctcgtgaaacaggagctgaaagaccgtgaggaggttgaagcacaaataaatgttgtg aagacttggatccaggaaacaaaagaatatttattaagccctaatgtggaactggatact caacttcaggagctgaagtctctcttctgtgaagtaactactcatcgccaggctgttgaa 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gccctgaggattcctgaagaggtggtcaccagcctgccaatatgtcacagtgcactccag ctccaggaggaggccagccgcctgcagcacactgccatccagcagtgcaacatcatgcag gaagctgtggttcagtatgagcaatatgagcaagagatgaaacatttacagcaaatgata gagagcgcccatcgtgagatccaagacaagccagtagcaaccagcaacatccaggaactc cagaaccagatttcacgtcatgaggagctggcgcagaagatcaaaggataccaggagcaa attgcttctttgaattcaaagtgcaagatgctaacgatgaaagcgaaacatgccactatg cttctgacagtgacagaagtagaggggctttctgaaggagtggaagagctggattcagac cttctcccggcacaccctgcacatccctcagtggttatgatgactgctggtcgctgtcac acactgctctcccctgtcactgaagagtctggggaggagggaaccaacagtgagatctct tctccacctgcctgtcgctctccctcacctgtggctaatacagatgcttctgttaaccag gacattgcatattaccaagccttatctgctgaacagttgcaaacagaagctgctaaaatt cagcccagcacttcagccacccaagagttttatgaaccaggcttagaatcagctgctagt gccaaactggatgatttgcagcgttcttgggaaacactgaagaatgtgataagtgaaaag cagcgcacactttatgaagctcttgagcgtcaacagaaatatcaggacacgcttcagtct atatctacaaaaatggagaccactgagatgaaactgaatgagagtctggaaccagccaag agcccagagagccagatggctgaacatcaggctttgatggatgagattctaatgttacaa gaagaaatcaccgagcttcagacatcattagcacaggagctggtttcagaatcactggat gcagaagctgctgaccagctggcattgcagtccactctcacagtcttggcagagcgaatg gccacaattcgaatgaaggcatcaggaaaaaggcagctattagaggaaaaactaagtgag caactggaagaacagcgacaagaacaggctcttcaaaggtaccgctgtgaagctgatgag cttgaccactggctactcaatacccgagcaacgctggacactgctctggttactgctgag gaacctatggatatggaagctcagctggtagattgtcagaacatgctggttgaaatagag cagaaggtggtggccttatcagagctttctgtgcacaacgagaacttgcttatggaaggg aaagctcacactaaggatgaggcagagcagctggctttgaagctcaggacactgaagggc agtcttctggagctgcagaaagttctccatgataaacagatcaacattcagcagggatca ctacaagaaaaagaggaaagcaatctggatttggtttcctcacagagtcccagtgtccaa gaatggctggcacaagcaaggactactcgatcacagcaacagcagagcactctacagcaa cagaaagagctggaacaggaactagaagagcagaagaatttgcttcgatcagtagcatgc cgtggagaagaaattttaacgcagcaaggtactccagaaggcttacgtataagtgagaag cctgagaagctctctgaagaactgtgcttggaaggtgagaaatcatctcctgaacaacag ctgaagataaaatgggaaagcctgaaccacaaattcagtaccaagcagaagcttctccag aaaactttggaacaagagcaactgcagatctatagcagaccaaatagactcatttctgga ctgcctttgtataaggagaatggacaggatgaggagaaatcatctgtgtcaccagtattg gttgaactaaatcaggcctttgaagatgcatcatctgagactggacatgtggagaaggaa agtctacatcttgaacagaagctgtatgatggagttgcatctacctccttatggctagat ggtgtggaagaacaggtatttgttgctacagctctgctgccggaggaagaaacagaaaca tacctctgcaaacaggagtctcttgccaaagaaatcaaagacataacagaagaaatggat aagaacaagaatttatttactcagatatttcctgagaatggtgataatagggaagttata gaagacactttggattgtctcctgagaagactgaccttactggagtcagtagtaaaccag agaagccatcagatgaaagagaggctccaggaaataatgaccttcaagaatgacctgaaa ctgctgtatacttcactggctgacagcaaatacttggttctacagaaactagcagaggca gttgagaaaccggaaacagaacaaattcaggtcataatgcaggcagaagaaagtttgaag gaattagatgctggaatcagtgaattaaagaagagtgtagataagctacaaatagaccag ccttctgtacaagagctatgtaagctacaggatatgtatgatgaggtgatgatgataatt ggatccaggcggagtgacctgaaccagaatctggctcttaaaaggcaatacgagcgggct ttgcaggacctggctgatttggtagaaacaggccaagaaaagatggatggtgaccagaaa atgatagttgcttctaaggaagaggttcaatcactacttaacaagcataaggaatatttt caggggttggagtctcacatgatcctgacagagacactctccagaaagatgagtagtttt gcccttttgaaggaaattcaatcacatccagaactaatgacacaagcttcaactgtatta aagctggcacataaacgaggtgtggagctggaatacattctagagacttggatacatctt gatgaagattaccaggaacttaccagacaactggagtctgtcgaaggtagcattcctgct gttggtttggtggaagagacagaagacaagctcatagaacggattaaactttttcagcat ctgagatctaacctgactgaatatcagcctaaattataccaggtgctggatgatgggaaa aggctacttttttctgttagttgctcagaccttgaaagtcagctgaaccaactgggagaa cactggctaagtaacaccagcaaggttaacaaggaacttcacaggctggagacaatactg aagcactggacaaggtatcaaagtgaatcaatagaactgacacactggttacagtctgca aaagagcgacttgagttttggagtcagcagtctctgacagttcctcaggaactggaaact gttcgagaccacctgaattcctttttggagttttcgaaagaagtggatgctaaatcatca cagaaatcttctgtactgagtactgggaaccagctcctcagactgaagaaggtagataca gcagcgttgcgtgcaggattgtcccacattgacagtcagtggacagagctactcacacac atcccaatagtacaagagaagttgcaccagctgcagatggacaaaattccttctcgccat gctatcactgaagttatgagctggatttccctgatggaaaatgttattcataaagatgag gagagtataaaaaacataataggacaaaaagccattcaggattatgtccaaaaatacaag ggtttcaagatagatttaaattgcaaacagttgactatagactttgtgaaccaatctgtg ctacaaattagcagccaagatgttgaaagtaaacgtagtgacaaaactgattttgcagaa cagctcggtgcaatgaatagacgttggcagattctacaaggcttggtaacagaaaagatc cagctgttggaaagtttgcaggaatcctggacagaatatgaaaataatgtgcagtgccta aaatcttggtttgaaacccaagagaagaagctgaaaaaacaacagagaattggagaccag gcttcagtacagaatgctttgaaagattgtcaggaattagaagaatcgataagaacaaag gaaaaagaattagaaagcatagaaaaaagtggtctgtctttgatacaaaacaagaaggag gaagcctcttctgctgttttgaatacactgcaagaaatcaatcattcctgggccagcttg gatcacgtggttagccaactaaagatattgttgcagtctgttcttgatcagtggagcatt tacaaagtaacatatgaagaactaaatagttacctgatggaagccagatactctttgtcc cgcttttatcttcttactggttctttggaagctgtgaaagtccaagttaataacctacag agcctacaagatgaactggaaaaacaagaaaacagcttacagaaatttggttccgtgacc aatcagttattgaaagaatgtcacccaccagtgactgaaacacttaccaacactttgaag gaagtgaatatgaggtggaataaccttatgcaagagattgcagagcgactacgttccagt aaaggtctccttcagctgtggcagaggtataaggactgttaccagcagtgctcttctact gtccgtttacgagaagaccagaccaatgaattgttgaagactgccactagtaaagacatt gctgatgatgaagtaaccacctggattcaagactgcaatgaccttcttgctgatataaag acagcacaggattcactgattgttcttcaggaactgggagaggagttaaaaagccgggtg gaggcctcagcagcagcagctatacagtctgatcagctgtctctaaaccagaatctgtca gccctagaacaagctctgtgcaagcaacaaactgtacttcaggctggagtattggactat caaacgtttgctaagaaactgcaagatctcgaggcctgggtaacagaagcagaagcaaag ctgaaaggacaggatcctggtcacgcatctgatctctcagcaatacagagtaggatggag gaactcaaaagtcagatgttgaaattcagcagcatggccccagatttggaccgtcttaat gagctgggttacaggcttcctctgaatgataaagaaatcaaaagaatccagaacctgaac agacaatggtctctgatctcgtctcagactacagagagattcagtaagctgcagtctttc ttgctacagcagcagacattcttggagaaatgtgaaacttggatggatttattagttcag actgaacagaagctggcagcagagatttcaggaaactaccagagtcttttagagcaacag aaagcacatgagctattccaggcagagatgttcagccgtcagcagattttgcattcaatc atctctgatggacagcgcctcctagaacaaggacaagtagatgacagggatgaatttaat ctgaagctgacacttctgagtaatcaatggcaaggagtaattcgtcgggcgcagcagagg agagggatcattgacagccagatccatcagtggcagcgctacagggaaatggcagagaaa ctacgcaaatggctggtggaaacgtcctgtcagccagtgagcggtctgggaaatgctcct atccctttgcagcaagctagagcattgctagatgaagtgcagcttaaagagaaagttctc ctaaggcaacaagggagttatatcctgactgtggaagctgggaagcaattgctgctctct gctgacagtggagctgaggcagccctgcaggcagagcttacagaaattcaggagcgatgg aagaaagttagcacccaactggaagaacagaagaagcaggttactttattactgaaagac tgggaaagatctgaaaagggaatagcagactccctggagaagctaagatcattcaaaaaa aagctttctcagcctttgccagaacaccatgatgagctgaatgcggaacagatacgttgc aaggaattagagaatgctgttgacggatggacagatgaccttgcacacctctctctgctg aaggagtccttgtctacctatataagtgcagatgatatttcagtcctcagtgagcgtata gagcttctgcacagacagtgggaggagctgtgccatcaggtatctttacgtcgacagcaa gttagtgagaaactgaatgagtgggctgtcttcagcgagaagaacaaggagctttgtgag tggctgacacaaatggaaagtaaagtttctcaaaatggtgacatcgtcatagaagaaatg atcgagaagcttagaaaggattatcaagaggaaattgctgtagcccaagagagcaaaatc cagctccagcaaatgggagagcgacttgctaaagccagccatgagagtaaagcatcagag attgagtacaaacttggcaagatcaatgacagatggcaacatctactggatctcattgca gccagggtaaagaagttgaaagaaacgctaattgcagtgcagcagctggataagaacatg agtagcctgagatcgtggcttgctcacattgaatcagagctgtccaaaccaattgtctat gaaacttgtgactctgaggagatacaaaggaagctaaatgaacagcaggaacttcagaga gacatagagaaacacagcactggagtggcatctgttctcaatttgtgtgaagtgcttctt cacgactgtgatgcctgtgccacagaaacagagtgtgactctatccagcaggctacacgc aatctggacagaaggtggaggaacatttgtgcaatgtcaatggaaaggcgacttaaaatt gaagagacgtggcggttatggcaaaagtttttggatgactactctagatttgaagactgg ctaaaaaactctgagaggacagctgctttcccaagctcctctggtgtgctttacacagtt gctaaggaagaactgaagaaatttgaggccttccagagacaggtgcatgaaagtctgact cagctggaactgattaacaaacagtatcgccgactggcccgggagaaccgcactgattcc gactgcagcctcaagcagatggtccatgaggggaaccagagatgggacaatttacaaaag cgagttacctccatcctgcgcaggctaaaacattttattggccagcgtgaggagtttgag acagcacgtgatagcatcctggtgtggctaacagagatggatctgcagttgaccaacata gagcatttctcagagtgtgatgtccaagcaaagataaagcaacttaaggctttccagcaa gaaatttcactgaacaacaacaaaattcaccagataattgttcagggtgagcaactcatt gagaaaagtgaaccgatggatgcagctgtcattgaagaagaactagatgagttacgccgt tactgtcaagaggtctttggacgtgtggaacgctatcacaagaaactgatccatcttcct ctgacagatgatgaacatgacctgtctgacaaagaggtggatttggatgaatcagcagat ctctctgacatacactggcatgaaaaatctgcagacagtgttctctccccacatccttct tccaacctctcactgcctcttgcacagccagtgagaagtgagcgatcagggcgggatacc cctgcaagtgtggactctatccctctggagtgggatcatgattatgatctaagcagagac ttggagacagctgtttcacgagcactgcactctgaggaggaagatggagaacaagagaag gatttctatctgagaggagcaactagtatagcagatgtagagatccctgaaactcttgag gcctatgtaacacttacagaaaacgcactcaaaaatatttctggagaacctggagcccta gaagcacatatacgacagctggacaaagccttagataccagtcgtttccaaatacagcaa acagaaaacatcatccgcagcaaaacacctacaggaccagagctggatgccacttacaaa ggatatatgaagctactaggtgaatgcagtggaagcatagactcagtaaaaaggcttgga tataagctgaaagaggaagaggaaaaattatctggacttattaatctgaacagtactgaa acacaaacagctggtgtaattgaccgatgggaattaatccaggctcaagctctaagcaag gagctaaggatgaagcagaatcttcagcaatggcagcagttcaattccgaccttaacagc atttgggcttggttaggagaaacagaggaagaactggagaagctccgccgccttgatctc agtactgacatacaaactatcgaactcaggattagaaaattgaaagagctgcagaaggca attgataaccgcaaagctatcatcttatccatcaacttgtgcagctcagaatttactcaa tccgacagtgaagaaagcaaaaaactccaagagcgcctgtctcagatgaacatctgctgg gatcacgtatgcagtatgatcgaagagtggcgctgctcactgcaagatgcgttaatgcag tgccaggatttccatgaaatgagccatggtctgctgctctggttagagaatattgacaga agaaaaaatgagattgtgcccatcaatccaaacctggattcagaaatcctacaggatcat cacagacttctaatgcaaatcagacgtgaactgctggaatctcagttgaaagtggcgtca ctgcaagatatgtcctgccaattgttagtcaatgctgaaggcaaggactgccttgaagcc aaagaaaaggtgcatgtcattggaaacagacttaagctcctcttgaaagaagtcatacgt cacataaaagacctagagaaagctctagacatttcaagtagtcagttggatttgtcctcg tggtcctctgctgatgaattagacacatcaggctcagtgagtcctgtatctggacaaagc acaccaagcagacagagaacgccacggggcaaatgtagtctctcacagcctggaccctct gtcagcagtccacatagcaggtccataagagatggctcaggttcctccccttctgaggct gggccagcatggcagcacccatccttcttcctcagagtcctcagagctgctctgccacta cagctccttttgctgctcctgattgggctggcttgcctggttccaatgactgaggaggac tacagctgtacaatggccaacaactttgcccgctctttccatcccatgttaaaatacatg aatggtccgcctccattatga

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