Mycolicibacterium hassiacum: MHAS_01543
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Entry
MHAS_01543 CDS
T05715
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mhas
Mycolicibacterium hassiacum
Pathway
mhas00300
Lysine biosynthesis
mhas00550
Peptidoglycan biosynthesis
mhas01100
Metabolic pathways
mhas01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhas00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MHAS_01543 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MHAS_01543 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MHAS_01543 (murF)
Enzymes [BR:
mhas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MHAS_01543 (murF)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF8449
Motif
Other DBs
NCBI-ProteinID:
VCT89844
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All DBs
Position
1:1652289..1653821
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AA seq
510 aa
AA seq
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MIPLTIAEVADIVGGRLADITAEQAAATRITGTVEFDSRRVTPGGLFLALPGARADGHDF
AAAAIESGAVAVLAARPVGVPAIIAPPATGDAQASVLEHDTDGSGAAVLAALAKLAAAVA
ARLVSRGLRIIGVTGSSGKTSTKDLIAAVLAPLGEVVAPPGSFNNELGHPWTVLRATEST
DFLVLEMSARRRGNIAALAAIAPPQIAVVLNVGTAHLGEFGSRHAIVETKAELPQSVPPD
GAVILNVDDPAVAGMADRTAARVVRVSRSPGADVWAGEVTLDELARPRFRLHAGDRAVEV
ALAVHGDHQVSNALCAAAVALECGAGLEQVAAALSNAGPVSAHRMQVVTRGDGVTVINDA
YNANPDSVRAGLKALVWMARQGAEPRRSWAVLGEMAELGEDAISEHDAIGRTAVRLDVSR
LVVVGTGRAMSAMHHGAVMEGSWGSESTMVPDADAALALLRSELQAGDVVLVKGSNAVGL
AALAEALIADAAPDGQTLTTQAPDPQDPTA
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgttgaccatcgccgaggtcgccgacatcgtcggcggccggctcgccgacatc
accgcagaacaggcggccgccacccgcatcaccggcaccgtggagttcgactcgcgccgg
gtcaccccgggcgggttgttccttgcactgccgggtgcccgcgccgacgggcacgacttc
gccgctgccgcaatagaatccggtgcggtcgcggtgttggcggcccggccggtcggggtt
ccggcgatcatcgcgccgccggccaccggtgacgcacaggccagcgtgctcgaacacgac
accgacggttcgggggcggcggtgctggcggcgctggcgaaactcgccgccgcggtcgcc
gcgaggctggtgagccggggcctgaggatcatcggcgtcaccgggtcgtcgggcaagacg
tcgaccaaggacctgatcgccgcggtgctggcaccgttgggcgaggtcgtcgcaccaccc
ggatcgttcaacaacgaactcggccacccgtggacggtgctgcgcgccaccgaatccacc
gactttctcgtgctcgagatgtcggcccggcgccgcggcaacatcgccgccctcgccgcg
atcgcaccgccgcagatcgcggtggtgctcaacgtcggcaccgcccatctcggcgagttc
ggttcgcgacacgccatcgtggagacgaaagcagaactgccgcaatcggttccgccggac
ggcgcggtgatcctcaacgtcgacgaccccgcggtggcggggatggccgaccgcaccgcg
gcccgggtggtgcgggtgtcgcgctcaccgggtgcggacgtgtgggccggcgaggtgaca
ctcgacgaactggccaggccccggtttcggctgcacgccggggaccgtgcggtcgaggtc
gcgctggccgtgcacggcgaccaccaggtgtcgaacgcgttgtgtgcggccgccgtcgcc
ctggagtgcggggccggcctcgagcaggtggcggcggcgctgtcgaatgccggtccggtt
tccgcgcaccggatgcaggtggtcacccgcggcgacggggtcaccgtcatcaacgacgcc
tacaacgccaaccccgattcggtgcgcgccggcctgaaggcgctggtctggatggcccgg
cagggagccgaaccgcgccgcagctgggcggtgctgggagagatggccgagctcggcgag
gacgcgatatccgagcatgacgccatcggccggaccgcggtgcgcttagatgtgtcacga
ctcgtcgtcgtgggaaccgggagggctatgagcgccatgcaccacggcgcggtgatggaa
gggtcatggggctccgagtccaccatggttcccgacgccgacgccgcgctggctctgctg
cgctccgagctgcaggccggagacgtggtgttggtcaagggctcgaacgcggtcgggttg
gccgccctggccgaggccctgatcgccgacgcggctcccgacggacagaccctcaccacc
caggccccagacccccaggatccgaccgcatga
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