Mannheimia haemolytica USDA-ARS-USMARC-184: B824_4920
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Entry
B824_4920 CDS
T03786
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mhat
Mannheimia haemolytica USDA-ARS-USMARC-184
Pathway
mhat00270
Cysteine and methionine metabolism
mhat00480
Glutathione metabolism
mhat01100
Metabolic pathways
mhat01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mhat00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
B824_4920 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
B824_4920 (gshAB)
Enzymes [BR:
mhat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
B824_4920 (gshAB)
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Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
Dala_Dala_lig_C
ATPgrasp_ST
GARS_A
GSH-S_ATP
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AJE07287
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All DBs
Position
385333..387609
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AA seq
758 aa
AA seq
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MKLQKLIRENHLALLFQQGNFGLEKESQRVDRNGNIVTTPHPAVFGNRSYHPYIQTDFAE
SQLELITPPNAKLEDSFRWLSAIHEVVLRSLPEEEYIFPLSMPAGLPPEEQIQEAQFDNP
EDVQYRQHLSKNYGKYKQMVSGVHYNFQLSTEFVEKAFALQTEYSELKAFQNALYMKLAN
NFLRYQWILLYLLAATPTVESQYFYEKSPLARGQLVRSLRSSPYGYVNSEKVVVNHDSLE
SYVESLEANVANGLLIAEKEFYSNVRLRGGKKARELLENGVKYAEFRLFDLNPFAPYGIE
LNDAKFIHYFLLGMLWLEETSGQKEVEIGKQKLYQVALEDPRTETAFRAEGEAILNQLLA
MLEELSAGQESLDLVREKLAQFADPSKTLNGRLIAAIEEVGSYKALGAKLAQTYKAQAFE
RFYALSAFDNMELSTQALFFDLIQQGIEVEVLDENDQFLALKFGDHLEYVKNGNMTSRDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTNLEQAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQAVKNREDFAKAVEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVV
GDGIHSVKELVERKNDDPLRGDGSRSPLKKIALGEIEQLQLKEQGLTVDSVPAKGQTVQL
RANSNISTGGDSIDMTDQMHESYRQIAVGIAQAMGAKVCGVDLIIPDLTKPAEPNLSSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVIKMLFPEIGN
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgaaactacaaaaacttatccgagaaaatcatttagcattgctatttcaacaagggaat
tttgggcttgagaaagagagccaacgggttgatcgcaacggcaatatcgttactactccc
caccctgccgtattcggtaatcgctcttaccacccttatattcaaaccgattttgccgaa
agtcagctagagttaatcactcccccgaatgctaaattagaagacagttttcgttggctc
tctgctattcacgaagtggtattgcgttcgttgccagaggaggaatatatcttccctctc
agtatgccggcaggcttgccgccggaagagcaaattcaagaagcacaatttgacaaccct
gaagatgtgcaatatcgccaacacctttccaaaaactatgggaaatataagcaaatggta
agcggcgtgcattataattttcaactttcaacggaatttgtcgaaaaagcctttgcttta
caaacggaatatagcgagctgaaagccttccaaaacgcactttatatgaagttagctaat
aactttttgcgttatcaatggattttgctctatttattggctgccacgcctacggtggaa
tcgcaatatttttatgaaaaatcaccgcttgcgagagggcaacttgtccgcagcttgcgt
tcaagcccttatggttatgtgaattcggaaaaagtggtggttaatcacgacagcttagaa
agctatgttgaaagccttgaagccaatgttgccaacggattattaattgccgaaaaagaa
ttctattccaatgtgcgtttacgagggggcaaaaaagcccgtgagctattggaaaacggt
gtgaaatacgccgaattccgtttatttgatttaaaccctttcgccccttacggcattgag
ctgaatgatgccaaatttatccattatttcttactcggtatgctttggctggaggaaaca
agcggtcaaaaagaggtcgaaatcggcaaacagaaactttaccaagtcgcacttgaagat
ccaagaacagaaaccgctttccgtgccgaaggtgaagccattttaaatcaacttttagcg
atgcttgaagaattatctgccggtcaggaaagcctagatttggtgcgggaaaaattagct
caatttgctgatccaagcaaaaccctgaacggacgtttaattgccgcaatagaggaagtc
ggcagttataaagcattgggggctaaattggctcaaacctataaggcacaagcctttgag
cgtttttatgcgttatcggcatttgataatatggaactttccacccaagccctgtttttt
gatttgatccaacaagggattgaggtggaagtactggacgaaaacgatcaattcctcgcc
ctgaaatttggcgatcatttggaatatgtgaaaaacggcaatatgaccagccgagatcaa
tacatttcaccgctgattatggaaaacaaagtggtgacgaaaaaagtattggcaaaagcc
ggctttaacgtgccgaaaagcgttgaatttaccaaccttgaacaggctgtggcacattat
ccgctatttgaaggcaaagcggtggtgattaagccgaaatcgactaactatggtttaggg
attaccatcttccaacaagcggtcaaaaatcgagaagattttgcaaaagcggttgaaatt
gcgttccgtgaagacaaagaggtgatggtggaagactatttagtcggtactgaataccgc
ttctttgtactgggcgatgaaacccttgcggtgttactgcgtgtaccggcgaatgtagtg
ggagatggcattcacagtgtaaaagagctggtggagcgtaaaaatgacgatccgctacgt
ggcgatggctctcgtagcccgttgaaaaaaattgccttaggtgaaattgagcagttacaa
cttaaagagcaaggcttaaccgtagattccgtaccggcgaaaggtcaaacagttcaactg
cgtgccaattccaacatcagcaccggcggcgattcgattgatatgaccgaccaaatgcac
gaaagctatagacaaattgcagtgggaattgctcaggcaatgggggctaaagtgtgtggg
gtggatttgatcattcctgatctcaccaaacctgccgagccaaatttaagctcttggggc
gtcattgaggcaaacttcaacccaatgatgatgatgcacattttcccttaccaaggcaaa
tcccgccgtttaaccaaagcggtaatcaaaatgctgtttcctgagataggcaattaa
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