Mannheimia haemolytica USDA-ARS-USMARC-184: B824_9070
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Entry
B824_9070 CDS
T03786
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mhat
Mannheimia haemolytica USDA-ARS-USMARC-184
Pathway
mhat00290
Valine, leucine and isoleucine biosynthesis
mhat00620
Pyruvate metabolism
mhat01100
Metabolic pathways
mhat01110
Biosynthesis of secondary metabolites
mhat01210
2-Oxocarboxylic acid metabolism
mhat01230
Biosynthesis of amino acids
Module
mhat_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mhat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
B824_9070 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
B824_9070 (leuA)
Enzymes [BR:
mhat01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
B824_9070 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NAD_binding_10
Motif
Other DBs
NCBI-ProteinID:
AJE07702
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All DBs
Position
793114..794658
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AA seq
514 aa
AA seq
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MSNNNIIIFDTTLRDGEQSLKASLTVKEKLQIALALERLGVDVMEVGFPVSSAGDFESVQ
TIARHIKNSRVAALSRAVAKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVV
EMAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNE
YGNIIHQVMNRVPNIDKAIVSVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNT
ALEEVVMAIKTRQEFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGI
HQDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYTETDYDLDKLYEA
FLQLADKKGQVFDYDLEALAFIDMQQGDEDRLKLDVITTQLISGLPASAFVQVELDGVRQ
SATSQGGNGPVEATYNAIMNIVGMELKMSHYNLTAKGEGAEALGQVDIVVEYEGRKFHGV
GLATDIVESSARALIHAINAIYRSQKVADLKAKK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgagcaacaataacattattatttttgatacgactttacgtgatggtgagcaatcatta
aaagcaagtttaaccgtaaaagaaaaattgcaaattgcccttgctttagaacgtttaggg
gttgatgtgatggaagtcggttttccagtttcttcagcgggcgattttgaatcagtacaa
accatcgctcgtcatatcaaaaacagccgggtggcggcgctttcccgagcggttgcaaaa
gacattgatgcagcttatgaagccttaaaagtagcagaagcattccgtatccataccttt
attgccagctcggcattacacgttgaggctaaattaaaacgttcatttgatgatgtagtc
gaaatggcggttgcagcggtaaaacgcgccagaaattatactgatgatgttgagttttcc
tgtgaagatgctgggcgtactggaattgataacatctgccgcattgtagaagctgccatt
aatgccggtgcaaccacagtgaatattccggatacagtcggtttctgtttaccgaatgaa
tacggcaatattatccaccaagtgatgaaccgtgttccgaatatcgataaagcgattgtc
tctgttcactgccataacgatttaggtatggctaccgccaactcattgacagcggtgcaa
aacggagcgagacagattgagtgtactatcaacggtattggcgaacgtgccggtaacacc
gctcttgaagaagtggtaatggcaattaaaacccgccaagaatttatgggggttgatacc
cgcattaatacccaagaaattcaccgtgtcagccaaatggtcagccagctttgcaatatg
ccgattcagccgaacaaagcgattgtcggtagcaatgcctttgctcactcttcaggtatt
caccaagacggtatgctgaaaaataaaaatacttatgaaattatgtcgccggaaaccatc
ggcttgaaaaaagagaagctgaatttaactgcccgttcaggtagagcagcggtgaaaggg
catatggctgatatgggttatacggaaacggattacgatttagataaactttatgaggcc
ttcttgcaacttgctgataaaaaagggcaagtgtttgattatgacttagaagctcttgcc
ttcattgatatgcagcaaggcgatgaagaccgcttaaaattagatgtaattaccacccaa
ctaatcagcggtttaccggcttcggcttttgtacaggtggaattagacggcgttcgtcaa
agtgctacatctcaagggggaaatggtccagttgaggcaacttacaatgccattatgaac
attgtgggaatggagctaaaaatgtcgcactataatctgactgcgaaaggcgaaggagca
gaagcattagggcaagtggatattgtagtggaatatgaaggtcgaaaattccacggtgtg
ggtttggcaaccgatattgtggaatcttcagcccgagctttaattcacgccattaatgcg
atttaccgttcacaaaaagtggcagatttaaaagcgaagaaataa
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