Micromonospora halotolerans: RMN56_19430
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Entry
RMN56_19430 CDS
T09415
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mhaw
Micromonospora halotolerans
Pathway
mhaw00280
Valine, leucine and isoleucine degradation
mhaw00640
Propanoate metabolism
mhaw00785
Lipoic acid metabolism
mhaw01100
Metabolic pathways
mhaw01110
Biosynthesis of secondary metabolites
mhaw01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mhaw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
RMN56_19430
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
RMN56_19430
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RMN56_19430
Enzymes [BR:
mhaw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
RMN56_19430
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
PFOR_II
Transketolase_C_1
DUF6059
Motif
Other DBs
NCBI-ProteinID:
WNM37341
UniProt:
A0ABY9ZSK8
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All DBs
Position
4080380..4083034
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AA seq
884 aa
AA seq
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MLSDVTTPQDLDDRFRAALTALGAPAQRRDLGEPLPGGGSLTGAQALALFDAQLTSRLLD
LAGRWLRSFGEGYYTIGSAGHEGNAAVAAALRPTDPALLHYRSGAFYCLRAAQAAGRFPV
GAEVPDADVPEPTGAAARIPDPRTPGDGDADADSGAPDGPPEAAAPDAPVTPGESARAGA
TSPYGGAEAAGDGAGPSGGSPAADDGAASLPTGAGVAVDTDGAAIAGVPEVPLPEPDDAY
AEAARDVLRGMVASAAEPIAGGRHKVFGRADLAVIPTTSTIASHLPRAVGLGLALERLRR
GGRRADGEPDAVTWPPDAIVVCSFGDASVNHATATAAFNTAGWYDHTGLRIPVLFVCEDN
GLGISVRSPQGWVAATLRARPGTRYFSADGTDVAEAYRVAGEAAAWVRRHRRPAVLHLTT
VRLMGHAGADAETAYRSPAEIAADLARDPLLATARRLVEAGCASGEELLARYDERGWQIR
RLAEEVLDEPKLTSPVDVVAELAPRRPVRISRAVADAATRAAGPDAGARAEAFGGKLPEL
AGPLTLAQSINAALADGMLDHPGVAVFGEDVAAKGGVYGVTKGLRDRFGAARVFDTLLDE
TSILGLALGAGVAGMLPVPEIQYLAYLHNAEDQLRGEAATMRFFSRGAFRNPMVVRVAGL
AYQEGFGGHFHNDNSVAVLRDVPGLVVAVPARPDDAAPMLRTCLAAAAVDGAVSVFLEPI
ALYHTRDLYTEGDGEWLAEYAEPGAWAARHVPIGRARVYGVGSAEDLTIITFGNGVRMSL
RAAATLADEGVGSRVVDLRWLAPLPVADIIREAAATGRVLVVDETRRSGGVGEGVIAALV
DGGYVGTARRVAGLDSFVPLGPAARQVLVSEDAITEGARTLLAR
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccgacgtgaccaccccgcaagatctcgacgaccggttccgggcggcgctgacc
gcgctcggtgcccccgcccagcggcgtgacctgggtgaaccgctgcccggcggcgggtcg
ctgaccggggcgcaggcgctggccctgttcgacgcccagctgaccagccggctgctcgac
ctggccgggcgctggctgcgcagcttcggcgaggggtactacacgatcggctccgccggc
cacgagggcaacgcggccgtggccgccgcgctgcggccgaccgaccccgccctgctccac
taccgctccggggccttctactgcctgcgtgccgcccaggcggcgggccgcttccccgtc
ggcgcggaggtgccggacgccgacgtgccggagccgaccggggcggcggcgcggatcccc
gacccgcgcacccccggcgacggcgacgcggacgcggattccggcgcgccggacgggccg
ccggaggcggccgcaccggacgccccggtgacgcccggcgagtccgcgcgggccggcgcc
acgagcccgtacggcggggccgaagcggctggtgacggggcgggcccgtccggtggctcg
ccggcggccgacgacggggcggcgagcctgcccaccggggcgggggtggccgtcgacacg
gacggcgccgcgatcgccggcgtaccggaagtgcccctgcccgagcccgacgacgcctac
gcggaggcggcccgcgacgtgctgcgcgggatggtcgcctccgccgccgaaccgatcgcc
gggggccggcacaaggtcttcggccgggccgacctcgcggtcatcccgaccacctccacc
atcgcctcgcacctgccccgggccgtcggcctgggcctggccctggaacggctgcgccgg
ggcggccggcgggccgacggggaacccgacgccgtgacctggccgccggacgccatcgtg
gtctgctcgttcggcgacgcctcggtcaaccacgccaccgcgacggcggcgttcaacacc
gccggctggtacgaccacaccgggctgcgcatcccggtcctgttcgtctgcgaggacaac
gggctcggcatcagcgtgcgctcaccgcagggctgggtggccgcgaccctgcgggccagg
ccggggacccgctacttctcggcggacggcaccgacgtggccgaggcgtaccgggtggcg
ggggaggcggcggcctgggtgcgccggcaccggcggccggccgtgctgcacctgaccacc
gtgcggctcatggggcacgccggggcggacgccgagaccgcgtaccggagcccggccgag
atcgcggcggacctggcgcgggacccgctgctggccaccgcccggcggctggtcgaggcc
ggctgcgcctccggcgaggaactgctggcccggtacgacgagcgcggctggcagatccgc
cggctcgccgaggaggtgctggacgagccgaagctgacctccccggtcgacgtggtggcc
gagctggccccgcgccggcccgtccgcatctcccgggcggtcgccgacgcggcgacccgg
gcggccggcccggacgccggtgcccgggccgaggcgttcggcggcaagctgccggagctg
gccgggccgctcaccctggcgcagagcatcaacgcggccctggccgacgggatgctcgac
caccccggggtggccgtcttcggcgaggacgtggccgccaagggcggggtgtacggggtg
accaaggggctgcgggaccggttcggggcggcgcgggtgttcgacaccctgctcgacgag
acctcgatcctcgggctcgcgctgggtgcgggggtggccgggatgctgccggtgccggag
atccagtacctggcgtacctgcacaacgccgaggaccagctccggggcgaggcggcgacc
atgcggttcttctcccggggggcgttccgcaaccccatggtggtgcgcgtggccggcctg
gcgtaccaggaggggttcggcgggcacttccacaacgacaactcggtggccgtgctccgc
gacgtgccggggctggtcgtcgcggtgccggcccgcccggacgacgccgcgccgatgctg
cgtacctgcctggccgccgccgcggtggacggcgccgtcagcgtcttcctggagccgatc
gcgctttaccacacccgcgacctctacaccgagggcgacggtgagtggctggcggagtac
gccgagcccggcgcctgggcggcccgccacgtgccgatcggccgcgcccgggtgtacggg
gtcggctcggccgaggacctcaccatcatcaccttcggtaacggggtccggatgtcgctg
cgggcggcggccaccctggccgacgagggggtcggcagccgggtggtggacctgcgctgg
ctggcgccgctgccggtggcggacatcatccgggaggccgcggccaccggccgggtgctg
gtcgtggacgagacccgccgctcgggcggggtgggcgagggcgtgatcgccgcgctggtg
gacggcgggtacgtcggcacggcgcgccgagtggccggacttgactcgtttgtaccatta
ggtccggcggctcgtcaggtcctggtctccgaggatgccattaccgagggtgcccgcacg
ctgctggcacggtaa
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