Marinithermus hydrothermalis: Marky_1444
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Entry
Marky_1444 CDS
T01457
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mhd
Marinithermus hydrothermalis
Pathway
mhd00300
Lysine biosynthesis
mhd00550
Peptidoglycan biosynthesis
mhd01100
Metabolic pathways
mhd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Marky_1444
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Marky_1444
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Marky_1444
Enzymes [BR:
mhd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Marky_1444
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEB12179
UniProt:
F2NMK9
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Position
1454582..1455865
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AA seq
427 aa
AA seq
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MMHEPRIDPNWAAAHTAGVAAPAAEAARDLVWDSRQVTPGAAFVALPGTRTHGNAFIEDA
VARGAAFVLTDRPHPKAVQVQDPWQALLRLGRALRDRFPGPVVGVTGSVGKTTTKEALAQ
GLAWPAPEGNLNTPPALARFFLHLPPQAPGAVVELGIDRVGEMQELVFLAQPTIGVLTAI
APAHLEALGSLEVVAREKSQLLQASRVRIASTQAARYLSLPEVRTYGFEEGTFQGRDLTI
TPEGTRFRYGQRTLHLPYPGYGPALGALAALAVAEVLGQDLDQVCQHLEALRLPPGRMHL
VRRGGVLFIHDAYNANPASVRAGLESLDRFPGRKIVVLGTMKELGPQAEAYHLEAARLAA
RVAQRAVFVGEYAPQMARLFEGALAVTDAETARQALKAQVRPGDVIYLKASRAVGLERVL
EGWDEDA
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgatgcatgaaccgcggatcgacccgaactgggccgccgcgcacaccgccggcgtggcc
gcccccgccgccgaagcggctcgagatctggtctgggactcccgccaggtcaccccaggc
gcggccttcgtcgcactccccggcacccgcacccacggcaatgccttcatcgaagacgcc
gtagcgcgcggcgcggcgttcgtgttgaccgaccgcccccaccccaaggcggtgcaggtc
caggacccctggcaggccctattgcgcctcggacgcgcgctcagggaccggtttcccggc
ccggtcgtgggcgtcacgggcagcgtagggaaaaccaccaccaaggaagccctcgcgcaa
ggcctcgcctggcccgctcccgaaggcaacctgaacaccccgccggccctcgcccgattc
ttcctgcacctccccccccaggctcccggagccgtcgtcgagctcggcatcgaccgcgtc
ggtgagatgcaggaactggtcttcctcgcccagcccaccataggagtactcaccgcgatc
gccccggctcacctcgaagcgctcggcagcctcgaggtcgtggcccgcgaaaaaagccag
ctcctccaagccagcagggtacggatcgcgtccacccaagccgcacgctacctctccctg
cccgaggtgcgaacctacgggttcgaggaaggcaccttccaagggcgcgacctcacgatc
acccccgaaggcacccgattccgctacggtcagcgcaccctccacctcccctaccccggg
tacggccccgccctgggagccctcgccgctctggccgtcgccgaggtgctcgggcaggac
ctcgaccaggtttgccaacacctcgaggccctgcgccttcccccagggcgcatgcacctc
gtgcggcgcggcggcgttctcttcatccacgatgcttacaacgcgaaccccgcctcggtc
cgcgccggcctggagagcctcgaccgcttccccggccgtaagatcgtcgtgctcggcacc
atgaaggaactcggcccccaagccgaggcctaccacctggaagcggctcgcctcgcagct
cgcgtcgcgcaacgcgccgttttcgtcggggagtacgccccgcaaatggcccgcctcttc
gagggcgccctcgccgtcacggacgccgagaccgcacgccaagccctaaaagcacaagtg
cgccccggggacgtcatctacctcaaagcctcgcgagccgtaggcctcgaacgcgtactg
gaggggtgggatgaggatgcgtga
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