Mycobacterium heckeshornense: JMUB5695_02201
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Entry
JMUB5695_02201 CDS
T07325
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mhek
Mycobacterium heckeshornense
Pathway
mhek00300
Lysine biosynthesis
mhek00550
Peptidoglycan biosynthesis
mhek01100
Metabolic pathways
mhek01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhek00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
JMUB5695_02201 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
JMUB5695_02201 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
JMUB5695_02201 (murF)
Enzymes [BR:
mhek01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
JMUB5695_02201 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF5647
Motif
Other DBs
NCBI-ProteinID:
BCQ08763
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Position
2288749..2290281
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AA seq
510 aa
AA seq
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MIALTLAQIADIVGGELADISPQDAARLCVTGTVEFDSRKVTPGGLFLALPGARTDGHDY
AAAAVAAGAAAVLAARPVGVPAVVVTPRRDPTHDALAAVFQHDHDGSGAAVLSALAKLAA
AVAAELISKGLTVIGVTGSSGKTSTKDLLAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT
PSTDYLVLELSARHPGNIAALAAIAPPKIGVVLNVGTAHLGEFGSREAIAATKAELPQAI
PDTGVVILNADDPEVAAMADKTAARIVRVSRHPRTDAGPSDVWAGPVTLDELARPRFTLH
TDRHERGAAAEVQLGVHGEHQVGNALCAAAVAFECGARIEQVVASLAGAGPVSGHRMHVT
TRADGVTVIDDAYNANPDSMQAGLQALASIAHSRRRRSWAVLGEMAELGADAITEHDRVG
RLAVRLDVSRLVVVGTGRSMSAMHHGAVTEGPRRAEATMVADAEAALALLRAELRPGDVV
LIKASNAAGLGALADALIADVSGDGRGAGR
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
ttgatagccctgacgctcgcgcagatcgccgacatcgtcggcggcgaactcgccgacatc
tcgccgcaggacgccgcacggctgtgtgtcaccggaaccgtcgaattcgactcccggaaa
gtcacgcccggcggcctgtttttggcgctgcccggggcgcgcaccgacggccacgactac
gcggccgccgcggtggccgcgggcgcggccgcggtgctggccgcccggccggtgggagtg
cccgccgtagtggtaacgccccggcgcgaccccactcacgacgcgctggcggcggttttc
cagcacgaccacgacggctccggtgcggcggtgctgtccgcgctggccaaactggccgcc
gcagtggctgcagagctgattagcaaggggctcaccgtcattggggtcaccggatcatcg
ggcaagacgtcgaccaaggatctgctggccgctgtgctggcacccctcggcgaagtggtg
gcgccgccaggatcgttcaacaacgagctgggccacccgtggacggtgctgcgcgccacc
cccagcaccgactacctcgttctggaactgtcggcccgccatcccggcaacattgccgcg
ctggcggccatcgcgccgcccaagatcggagtggtgctcaacgtcggcaccgcgcacctg
ggcgagttcggctctcgagaagcgatcgctgcaaccaaagccgaactgccgcaagctatt
ccggacaccggagtggtgatcctcaatgccgacgatccagaagtggcggcgatggccgac
aaaaccgccgcccgcatagtgcgggtcagccgacacccgcgcaccgatgccggtcccagc
gacgtctgggccgggccggtcaccctcgacgagctggcccggcctcgcttcaccttgcac
accgaccggcacgaacggggcgcggccgccgaggtccaactcggtgtgcacggcgaacac
caggtcggcaatgcgctctgcgccgccgcggtcgctttcgagtgcggtgcccgcatcgaa
caggtggtcgcaagcctggccggtgccggtccggtgtcggggcaccggatgcacgtgacc
acccgtgccgacggggtcacggtgatcgacgacgcctacaacgccaacccggactcgatg
caggccgggctgcaggcgctggcctcgatcgctcacagccgtcggcgacgcagttgggcg
gtgctgggagagatggccgaactcggtgccgacgcgataaccgagcatgaccgcgtcggc
cggttggcggtgcgcttagatgtgtctcgtctcgttgtggtcggaaccgggaggtctatg
agcgccatgcaccacggcgcggtcaccgagggcccgcggcgggcggaggccaccatggtc
gccgacgccgaagccgccctggcattgctacgggccgaactgcggccgggggacgtggtg
ctgatcaaggcgtccaatgccgccggactgggcgcgctggcggacgcgctgatcgcggac
gtatccggcgacggccgaggcgctggccgatga
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