Mycolicibacterium helvum: MHEL_04050
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Entry
MHEL_04050 CDS
T07064
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00280
Valine, leucine and isoleucine degradation
mhev00640
Propanoate metabolism
mhev00785
Lipoic acid metabolism
mhev01100
Metabolic pathways
mhev01110
Biosynthesis of secondary metabolites
mhev01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MHEL_04050
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MHEL_04050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MHEL_04050
Enzymes [BR:
mhev01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MHEL_04050
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
BBY62162
UniProt:
A0A7I7SYR6
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Position
complement(436482..437531)
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AA seq
349 aa
AA seq
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MDQPIQLIAPDGSATAESRYRRDLPPETLVWLYENLVVTRDLDAEFVNLQRQGELALYAS
CRGQEAAQVGAAACLRKTDWLFPQFRELGVFLVRGIAPPQVAAVWRGAWHGGLDFTSRCC
APIAIPIATHALHAVGAAMAAQRLGEDSLTVAFLGDGATSEGDSHEAMNLAAVEKAPCVF
YIQNNQWAISVPASRQYAAPTIAHRAIGYGMPGIRVDGNDILACYAVMAEAAERARAGEG
PTLIEAVTYRMEPHTTSDDATRYRSAAELAEWSARDPISRYRTYLQHKGVLTERVDKRVE
ARSVRLRAELRDAVVGAPDPDVGELFDHVYAEITPVLSAQRAQLRAELA
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
atggatcaaccgattcaactcatcgcaccggacggaagcgcgacggccgagagtcgatat
cgtcgcgacctcccgccggaaaccctcgtctggctctacgagaacctcgttgtcactcgg
gatctcgacgccgagttcgtcaatctgcaacggcagggcgagctggcgctctacgcctcg
tgtcgcggtcaggaggccgcgcaggtcggtgcggcggcatgcctgcgcaagaccgactgg
ctgttcccgcaattccgtgaactcggtgtcttcctggtccgcggcattgcaccgccgcaa
gtggccgccgtctggcgcggcgcctggcacggtggcctggatttcaccagcaggtgttgt
gcgcccatcgctatccccatcgccacccacgcgctgcacgccgtcggcgcagcgatggcc
gctcaacgactgggcgaagattcgctgacggtggcgttcctcggtgacggcgccaccagc
gaaggggattcacacgaggcgatgaacctggccgccgtcgagaaggcgccctgcgtgttc
tacatccagaacaatcagtgggcgatctccgtgccggcgagccgccagtacgctgcgccc
accatcgcccaccgggcgatcggctacggaatgccgggaatcagggtggacggcaacgac
atcctggcctgctatgcggtgatggccgaagctgccgaacgcgcgcgggccggtgagggt
cccaccctcatcgaggcggtcacctatcggatggaaccgcacaccacctctgatgacgcg
acccgttaccgcagcgctgccgagctcgccgaatggtcggcccgcgatccgatcagccgt
taccgcacctatctgcaacacaagggggtgctcaccgagcgagtcgacaagcgggtggaa
gcccgctcggtgcggctgcgtgcggagcttcgcgacgcggtggtcggcgcgcccgaccct
gatgtgggtgagctgttcgaccacgtctacgccgagatcacaccggtgttgtcggcccag
cgcgcgcaattgcgcgccgaattggcgtag
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