Mycolicibacterium helvum: MHEL_09990
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Entry
MHEL_09990 CDS
T07064
Name
(GenBank) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00984
Steroid degradation
mhev01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
MHEL_09990
Enzymes [BR:
mhev01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
MHEL_09990
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
MHEL_09990
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
NmrA
Polysacc_synt_2
KR
adh_short
adh_short_C2
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
BBY62756
UniProt:
A0A7I7T3T2
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Position
1109236..1110297
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AA seq
353 aa
AA seq
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MGDATLTTDLGRVLVTGGAGFVGANLVTELLERGHFVRAFDRAASPLPPHERLEVIQGDI
CDTATVAAAVEGIDTVFHTAAIIDLMGGASVTDEYRKRSFDVNVGGTKNLVHAGQTAGVK
RFVYTASNSVVMGGQRIVNGDETLPYTARFNDLYTETKVTAEKFVLSQNGADGLLTCSIR
PSGIWGRGDQTMFRKLFERVIAGHVKVLVGNKDAKLDNSYVHNLVHGFILAAEHLVPDGS
APGQAYFINDGEPINMFDFSRPVVEACGEKWPTFWIPGGLVHAVLTGWQWLHFKFGLPQP
PLEPLAVERVSIDNYFSIDKARRDLGYAPLYTTEQALKECLPYYTELYAEMKG
NT seq
1062 nt
NT seq
+upstream
nt +downstream
nt
atgggtgatgccacgctgaccactgacctcggccgtgtcctggtgaccggcggcgccggg
ttcgtcggcgccaacctggtgaccgagctgctcgagcgcggtcacttcgtccgggctttc
gatcgcgcagcatcgccgctgccgccacacgagcggctcgaggtgatccaaggcgacatc
tgcgacaccgccactgtggccgccgcggtcgagggcatcgacacggtcttccacaccgcc
gcgatcatcgacctgatgggcggggcgtcggtcaccgacgagtaccgcaagcgcagcttt
gacgtcaatgtcggtggcaccaagaacctggtccacgccggacagaccgccggggtcaag
cgcttcgtctacaccgcatccaacagcgtggtcatgggtggccagcgcatcgtcaacggc
gacgaaaccctgccgtacaccgcacgattcaacgatctctacaccgagaccaaggtgacg
gccgagaagttcgtgctcagccagaacggcgcggacggcctgctgacctgttcgatccgc
cccagcggcatctggggccgcggcgatcagaccatgttccgcaagctgttcgagcgggtg
atcgccggccacgtcaaggttctggtcggcaacaaggacgccaagctggacaactcttac
gtgcacaatctggtgcacggattcatcctcgccgcagagcatttggtgcctgatggcagc
gcacccggccaggcgtacttcatcaacgatggcgaaccgatcaacatgttcgacttctcc
cggccggtcgtcgaggcctgcggcgagaagtggccgacgttctggatccccggcggcctg
gtccacgccgtgctgaccggctggcagtggctgcacttcaagttcggactcccccagccg
ccgctggaaccgcttgcagtggaacgggtgtcgatcgacaactacttctccatcgacaag
gcccgccgcgacctcgggtatgcgccgctgtacaccaccgaacaagctctcaaagaatgc
ctgccctactacaccgagctctacgcggagatgaagggctag
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