Mycolicibacterium helvum: MHEL_20690
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Entry
MHEL_20690 CDS
T07064
Symbol
ppsA
Name
(GenBank) phthiocerol synthesis polyketide synthase type I PpsA
KO
K15320
6-methylsalicylic acid synthase [EC:
2.3.1.165
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev01059
Biosynthesis of enediyne antibiotics
mhev01100
Metabolic pathways
mhev01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
MHEL_20690 (ppsA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
mhev01008
]
MHEL_20690 (ppsA)
Enzymes [BR:
mhev01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.165 6-methylsalicylic-acid synthase
MHEL_20690 (ppsA)
Polyketide biosynthesis proteins [BR:
mhev01008
]
Polyketide synthase (PKS)
Iterative type I PKS
Fungal partially reducing PKS (PR-PKS)
MHEL_20690 (ppsA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
PP-binding
KAsynt_C_assoc
PKS_DH_N
adh_short
PS-DH
Epimerase
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
BBY63826
UniProt:
A0A7I7T6T2
LinkDB
All DBs
Position
2220617..2225881
Genome browser
AA seq
1754 aa
AA seq
DB search
MLLWRSGRCAVAPEATVGQAEQGDPIAVVGIGCRVAGNVTTPAAFWTYLMEGRSDVREIP
EERWEPYLHRDPRNAAVLRDVTRRGTFLDALDAFDAEFFGVSPREAELMDPQQRLALEVS
WEALEHAGISPRSLAGSDTAVLMGVNSDDYGKLIMEDLPGIEAWTGIGTSLCGIANRVSY
LLDLRGPSVALDAACAASLVAVHQACQMLRAGETSLALAGGVSALIGPGLIRVLDEAGAT
APDGRCKTFDESADGYGRGEGAGVVVLKRLADATRDGDRVLAVVLGGAVAQDGRTVGIMS
PNGDAQAALFRRVCESSRVSPQSVDYVEAHGTGTPTGDPVEVNALAAVYGAGRDNDARCR
IGSVKPNVGHLEGGAGVIGLIKAVLALHHKAIPPTAGVRQLTSAVDWAASGLRVPTTVER
WESVDRPRRAAVCSYGYGGTIAHVLLQEAPESHVEAVDAPQADTPLIVPLSARSHERLKH
HADALADHLRTVSSPVAEIAATMWRRRAHDPIRAAVIAAAPHELTSGLDCIARGETTADV
TTGPALPGETRAPVWVFSGHGSHWVGMGRELLDTEPTFARVIDEVDEVFAAELGFSARDA
FTTGELGSTDRIQALTFAVQVGLAAVLGDRGVTPAAVIGHSVGEVAACVAAGVFDLRQGA
ALACYRARGFRSVLGQGAMALVRLPFAEAEARLTGHTDVVAAISASPETTVISGDTDAVL
AITHAWKAQGIETRQVNTDVAFHSPAMDALTGELARLVAGLHPSRPPAVPLYTTALDDAR
SQAPRGPEYWVANLRGRVRFAEAITAAAEDGHQLFLEVSAHPVVSHSIVETLLHLGIDEH
AVVPVLRRDQPERRAVAVAVASLWCHGAEVAPAVAPTDPWATDLPGTQWRHNRFWRVPTQ
PPGVRGVHDPQSHTLLGGRIDLAGTPDTCLWETQLDMSTRPYPGDHPVHGTEIVPAAVLL
NTLLTAAHGGEDIGAHCIGLADVRLRTPVLPSRPLDLQVVRNGRGLTLSTRRTGADTATD
GWLTHTSAVIAVGDDIDELLASRLDLDAARVRCAEALPPNHVIDTLADLGVAAMGFDWQI
TELMRDHGEILAVVKSNPHGAGATSWASLVDAATSTASTVFDTPGVRRCLRMPARIERVH
VHGPAPATATILVRRRPEGICTDAAIADDNGTVLLSIAGMAFEELENDGVSANNTQRMVH
HVGWRPVGVRPDEHPSGVVLVGGDGEGLNRMIDDLAAAGLPYRAIEDPADIGVGETIPDT
DRFPAELGATPVVLVLPRTDDTPEASVDLVLRTLVRLQNFGIQTRVWVRTTGVHEGTNLS
QAPLWGLARVAAAEHPALWGGAVDVLDGRFPFAMLPSLHGHGVVVVRDGVAQIARLAPTV
SRPASGAPLQCSPGGTYLITGGTGVLGLRMAQRLADLGARRLLLLSRSGVSPRSQWADEP
RGEAVAAITALEAQGVSVHVAAVDIAASDAADTLRAVMADLPPVLGVIHAAGVEAGALLM
NTSSEDIAATMRPKVHGALTLHRLFPPEQLEWMVLFSSCGYLAGFPGQGAYACANSFLDV
MARHRRRLGDRTTAIAWTAWRGLGMGSTSEYVAAQLDAFGMGTVTADDAMRALDIAMRDD
DPNIVVLPLLPSATALPIFADAVSDPEDEADSDGPAHPTKPGRVLDPDSLTQEVLGAVSV
QLGVPGTEVDPEVPLFELGVDSIMAVRLRRELEKQTGLSLPPTLLWEHPTTGAVTEKLAE
LLGFSREPQEVESA
NT seq
5265 nt
NT seq
+upstream
nt +downstream
nt
atgcttctatggcgttcgggacgctgtgccgtggcgcctgaagcgacggttggccaggcc
gaacagggcgacccgatcgccgtcgtcggcatcggctgccgggtagcgggcaacgtcacc
accccggccgcattctggacgtacctgatggaaggccgcagcgacgtccgggagattccc
gaagaacgctgggagccgtacctgcaccgagacccgcgcaacgccgccgtgttgcgggat
gtgacgcgtcggggaaccttcctcgacgccctggacgccttcgacgccgagttcttcggg
gtgtccccgcgcgaggcagagttgatggatcctcagcagcgccttgcccttgaagtgagc
tgggaggcgctcgagcacgcgggtatctctccgcgctcgctggccggcagcgacaccgcc
gtgctgatgggcgtgaactccgacgactacggcaagctcatcatggaagatctgcccggt
atcgaggcgtggaccggaatcggtacctcgctgtgcggcatcgccaaccgggtctcatat
ctgctcgacctgcgaggaccgagcgtcgccttggatgccgcgtgcgcagcgtcgctggtc
gcagtccatcaggcctgccagatgctgagggcgggcgagacctcgctcgccctggcgggc
ggcgtcagcgcgctgatcgggcccgggctgatccgagtgctcgacgaagcaggcgccacc
gcgcccgatggccggtgcaagacgttcgacgagtccgccgacgggtacggccgcggcgaa
ggcgccggtgttgttgtgctcaagcggttggccgacgccacgcgtgacggtgatcgggtg
ctcgccgtcgtgctcggcggcgccgtcgctcaagacggccgaaccgtggggatcatgtcg
cccaatggcgacgcccaggcggcgctgttccgacgggtgtgcgaaagttcgcgtgtctca
ccgcaatccgtggactacgtcgaggcgcacggcaccggtacgccgacgggcgacccggtc
gaggtcaacgcgctggcggctgtctacggagccggtcgcgacaatgacgcacggtgccgg
atcggatccgtcaagccaaacgtcggccacctcgagggcggagccggcgtgatcgggctc
atcaaggcggtgctggccctgcaccacaaggcgattccgccgactgccggcgtacgccag
ctcacctcggcggtggactgggcagcgagcggacttcgtgttcccaccacagtcgaacgg
tgggaatccgttgaccgcccacgccgcgcagccgtgtgcagctacggatacggcggcacc
atcgctcacgttctgctgcaggaggctcccgagtctcacgtcgaggcggtcgacgcaccg
caggccgacacgcccctaatcgtgccgttgtcggcccgatcacacgagcgtctgaagcac
cacgccgatgcgctggccgatcacctcaggacggtatcgtcgccggtcgccgagatcgcc
gccacgatgtggcgacgccgagcacacgatccgatccgagcggcagtcatcgcggcggca
cctcatgaactcacgtcgggcctggactgcatcgcgcgcggggaaaccaccgcagacgtg
accaccgggccggcgctgcccggtgagacccgtgcgccggtatgggtgttctccggtcac
ggttcgcactgggtcgggatgggccgcgagctgctcgataccgaaccgaccttcgcgcgg
gtcatcgatgaggttgacgaggtgttcgccgccgaactcggattctccgcccgcgacgcg
ttcaccaccggtgaactcggtagtaccgaccgcattcaggcgttgaccttcgcggtgcag
gtcggcctggccgcggtgctcggcgaccgtggggtcacgccggccgccgtgatcggacac
tcggtcggcgaggtggcagcctgcgtggcagccggtgtgttcgatctgcgtcagggcgca
gcgctcgcgtgctaccgagcccgggggtttcggtccgtgctgggccagggtgcgatggca
ctcgtccgactgccgttcgccgaagccgaagccaggttgacggggcacaccgacgtggtc
gccgccatcagcgcgtcacccgaaacgacggtgatctccggtgacaccgacgccgtgttg
gccatcactcacgcgtggaaggcccagggcatcgagacacgccaggtcaacaccgatgtg
gcattccacagccccgcgatggacgctctcaccggcgagctggcgcggctggtcgcaggt
ctgcacccgtcgcgcccgccagcggtgccgttgtatacgaccgccctcgacgatgcccgc
tcccaggcaccgcgcgggccggagtattgggtggcgaacttgcgcggccgggttcgattc
gccgaggcgatcaccgcagcagccgaagacggccaccagctgttcctggaagtatccgcg
caccccgttgtctcgcactcgatcgtggagacgttgctgcatctgggcatcgatgaacac
gctgttgtcccggtgctgcgccgtgaccaacctgagcgtcgcgccgttgccgtcgcggtc
gcgtcgttgtggtgccacggcgccgaggtcgcgcccgctgtcgcaccgacagatccgtgg
gccacggacctacccggcacgcagtggcggcacaaccggttctggcgggtaccgacacag
cctcccggagtgcgcggtgttcacgacccgcagagccacaccctgttgggtggacgcatc
gatctcgccggcacccccgacacgtgtctgtgggagacccagctggacatgtccactcgt
ccctacccgggcgaccatccagtgcacggaaccgaaattgtccctgccgcagtacttttg
aacacattattgaccgccgcccacggcggggaggacatcggcgcgcactgcatcgggctt
gccgacgtgcgactgcgcacaccggtactaccgagccgtccgctcgatctgcaggtggtg
cgcaacggccgggggctgacgctgtcgacgcggcggaccggcgcggacaccgcaaccgac
ggctggctcacgcacaccagcgccgtcatcgcggtcggggacgatatcgacgaacttctt
gcctcacgcctcgatttggacgccgcgcgggtgcgctgtgctgaagcattgccgccgaat
cacgtcatcgacacattggccgatctcggcgtagccgcgatgggtttcgactggcagatc
accgaattgatgcgtgaccacggggaaatcttggcagtcgtgaagtcgaatccgcacggt
gcgggtgcgacatcgtgggcctcacttgtcgatgcggccacctcgactgcgtctacggtc
ttcgatacgcccggtgttcggcgctgcctgcggatgcccgcgcgtatcgaacgcgtgcac
gtccacggccctgcccccgctactgcgacgatcctcgtacggcgacggccggaggggatc
tgcacagatgcagcgattgccgatgacaacggcaccgtgctgctgtctatcgccgggatg
gcgttcgaagagcttgaaaatgacggagtttcggcgaacaacacccaacgcatggtgcat
cacgttggatggcgcccggtgggcgtccgccccgatgaacaccccagcggagtcgtgctg
gtcggcggtgacggcgagggactcaaccgcatgatcgacgatctggcggccgccggattg
ccctatcgagccattgaagaccccgcggatattggtgtcggcgagacgattccggacacc
gaccggttccccgccgagcttggcgccacacccgtggtcctcgtgctcccgcgcaccgac
gacactcccgaagcctcagtcgatcttgtgctgagaacgcttgtgcggctgcagaacttc
ggaatacagacccgagtatgggtcaggaccaccggcgtacatgaaggtacgaacctcagc
caggcaccgttgtgggggctggccagggtggccgcagcagagcatcccgcgctgtggggc
ggcgctgtcgacgtactcgacggtcggttcccgttcgccatgctcccctcgctgcacggt
cacggtgttgtcgttgtccgcgacggtgtcgcccagatcgcgcggctggcaccgactgtt
tcgcgtcccgcgtcgggcgcgcctctgcagtgctcaccggggggcacatacctgatcacc
ggtggcaccggcgttctcgggttgcgcatggcgcagcgcctcgctgatttgggggcacgc
aggctgctgctgttgtcgcgctcaggtgtgtcgccgcggtcccagtgggcggacgagccc
cgcggtgaagccgtcgcagccatcacagcactggaagcccaaggcgtgtctgtccatgtc
gctgcggtcgacattgcggcctccgatgccgccgacacgctgcgcgccgtgatggccgat
ctgccacctgtgctcggcgtgatccacgctgcgggcgtggaggctggtgcactgctgatg
aatacgagctccgaggacatcgccgccacgatgcggcccaaggtgcacggggcactcacg
ctgcaccggctgttcccgcccgagcaactcgagtggatggtgctgttctcctcgtgcggg
tatctcgcgggcttcccgggccagggcgcctacgcgtgtgcgaactcgttcctcgacgtg
atggcgcggcaccgccgccgcctgggcgaccgcaccaccgcgatcgcctggacagcatgg
cgcggcctcggcatggggtcgacatcggagtacgtcgcggcgcaactggacgcattcggg
atgggaaccgtcaccgcagacgatgcgatgcgcgcgctcgatatcgccatgcgcgacgat
gaccccaatattgttgtgctgccgttgcttccgtcggccacagcgctacccatctttgcc
gacgccgtgtcggatccagaggatgaagcagattccgacggcccggctcaccccaccaaa
ccaggccgggtactcgacccggactcactgacgcaggaagtcctcggggcggtgtccgtc
cagctcggagtgcccggcaccgaggtggacccggaggtgccgttgttcgaacttggcgtc
gactcgatcatggccgtgcgattgcgacgtgagctcgagaagcaaaccgggctctcgttg
ccgccaacactgctgtgggagcatcccaccaccggcgcagtcaccgagaagttggcggag
ctgttgggtttctcgcgcgaaccgcaggaggtcgagtcggcgtga
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