Mycolicibacterium helvum: MHEL_26840
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Entry
MHEL_26840 CDS
T07064
Symbol
topA
Name
(GenBank) DNA topoisomerase 1
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
mhev
Mycolicibacterium helvum
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mhev03032
]
MHEL_26840 (topA)
03400 DNA repair and recombination proteins [BR:
mhev03400
]
MHEL_26840 (topA)
Enzymes [BR:
mhev01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
MHEL_26840 (topA)
DNA replication proteins [BR:
mhev03032
]
Prokaryotic type
DNA Topoisomerases
MHEL_26840 (topA)
DNA repair and recombination proteins [BR:
mhev03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
MHEL_26840 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Toprim_C_rpt
Toprim
Toprim_4
Rep_1B
Toprim_2
Motif
Other DBs
NCBI-ProteinID:
BBY64441
UniProt:
A0A7I7T7H3
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All DBs
Position
2870046..2872931
Genome browser
AA seq
961 aa
AA seq
DB search
MADDGTRLSGGDGRSNGNVRRLVIVESPTKARKIAGYLGANYIVESSRGHIRDLPRNAAD
VPAKYKSEPWARLGVNVEDNFEPLYIISPDKKSTVTELKGLLKDVDELYLATDGDREGEA
IAWHLLETLKPRVPVKRMVFHEITEPAIRAAAENPRDLDNDLVDAQETRRILDRLYGYEV
SPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSASYWDVIAELDASVSDPNATPPR
FTARLVNVDSKRVATGRDFDSLGVVRKPDEVVVLDEAAAGSLATGLQASSLAVASVEEKP
YTRKPYPPFMTSTLQQEAGRKLRFSAERTMSVAQRLYENGYITYMRTDSTTLSQSAIDAA
RNQARQLYGDEYVHPSPRQYTRKVKNAQEAHEAIRPAGDTFATPGALHRELDTDEFRLYE
LIWQRTVASQMADARGTTLSLRIAGVAGPTTLDAGVAGPTTLDAGVAGPTTLDSATSTGG
RDVVFAASGRTITFPGFLKAYVETVDEQAGGEADDAESRLPQLRQGQRVDATRLTADGHT
TNPPARYTEASLIKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLL
EQHFGRLVDYDFTAAMEDELDEIASGQERRTNWLTNFYFGGEHGVADSIARAGGLKKLVG
VNLEGIDAREVNSIKLFDDEEGRAVVVRVGKNGPYLERMVIGEDGELKPQRANLSDEITP
DELTLELAETLFATPQEGRVLGVDPESGHEIVARDGRYGPYVTEVLPPPPEEEGGVGAKK
GKKPTGPKPRTGSLLRSMDLQTVTLEDALKLISLPRVVGVDPANGEEITAQNGRYGPYLK
RGTDSRSLATEDQIFDITLEEALKIYAEPKRGGRQGAAAPPLRELGVDAASGQPMVIKDG
RFGPYVTDGETNASLRKGDDVLSITDERASELLADRRARGPVKKKAPAKKAARKKAPAKK
A
NT seq
2886 nt
NT seq
+upstream
nt +downstream
nt
ttggctgacgacggaacccgcctaagcggcggcgatggccgaagtaatggcaacgtccgg
cggctcgtgatcgtcgagtcgcccaccaaagcgcgcaagatcgccggctacctgggtgct
aattacatcgtcgagtcgtcccgtgggcacatccgtgacctgccgcgtaacgccgccgac
gtgccggccaagtacaaatccgagccgtgggcgcgtctcggcgtcaacgtcgaggacaac
ttcgagccgctctacatcatcagccccgataagaagagcactgtcaccgagctcaagggc
ttgttgaaagatgtcgacgagctctatctggccactgacggtgaccgcgagggtgaagcc
atcgcctggcacctgctggagacgctcaagccccgcgtcccggtcaagcggatggtcttc
cacgagatcaccgagccggccatccgcgcggccgccgaaaatccccgcgacctggacaac
gacctggttgacgcgcaggagacccggcgcatcctcgaccggctctacggctacgaggtc
agcccggttctgtggaagaaggtcgcgccgaagctgtcggcgggccgggtgcagtccgtg
gccactcggatcatcgtgcagcgcgaacgcgaccggatggccttccgcagcgcctcctac
tgggacgtgatcgccgagctcgacgcgagcgtctcggaccccaacgccaccccgccccgc
ttcaccgcccggctggtcaacgtcgacagcaagcgggtggccaccggccgggacttcgat
tccctgggcgtcgttcgcaagcccgacgaggtcgtggtgctcgacgaggccgccgcgggc
tcgctggccaccggtttacaggcctccagcctcgccgtggcgtcggtggaggagaagccg
tacacccgcaagccctatccgcccttcatgacctccacgttgcagcaggaggccggccgc
aagctgcggttctccgccgagcgcacgatgagcgtcgcgcagcggctctacgagaacggc
tacatcacctatatgcggaccgactcgacgacgctgtcgcagtcggccatcgacgccgcg
cgcaatcaggcgcgtcagctctacggcgacgagtacgtccacccgtcgccgcggcagtac
acccgcaaggtgaagaacgcgcaggaggcgcacgaggccatccggcccgccggtgacacc
ttcgccacccccggcgcactgcaccgcgagctcgacaccgacgagttccggctctacgag
ctgatctggcagcgcaccgtggcctcgcagatggccgacgcccgcgggaccacgctgagc
ctgcgcatcgccggagtcgctgggccgacgacattggatgccggagtcgctgggccgacg
acattggatgccggagtcgctgggccgacgacattggattcagccacgtccactggtggc
cgcgacgtagttttcgctgccagcggccgcaccatcaccttccccggcttcctcaaggcc
tacgtcgagaccgtcgacgagcaggccggtggtgaggccgacgacgccgagagcaggttg
ccgcagcttcggcaggggcagcgcgtggacgccacccggctgactgccgacgggcacacc
accaacccgccggctcgctacaccgaggcatcgctgatcaaagcgctcgaagaactcgga
atcggccgtccctcaacgtattcctcgatcatcaagacgatccaggatcgcggttacgtc
cataaaaagggcagcgctctggtgccgtcgtgggtggcgttcgccgtcaccgggctgctc
gagcagcatttcggccggctggtggactacgacttcaccgccgccatggaggacgagctc
gacgaaatcgccagcgggcaggagcggcgcaccaactggctgaccaacttctacttcggc
ggcgagcacggggtcgcggattcgatcgcccgcgctgggggcttgaagaagctggtgggt
gtcaatctcgagggtatcgacgctcgagaagtcaactccatcaagctctttgacgacgaa
gagggccgcgcggtcgtggtacgcgtcggcaagaacggcccgtacctggagcggatggtc
atcggcgaggacggtgagctcaaaccgcaacgggccaacctcagcgacgagatcactccc
gacgagctgaccctggaattggctgaaacccttttcgccacaccgcaagagggtcgtgta
ctcggcgtggatccggagtccggtcacgagattgtggccagggacggccgatacgggcct
tatgtcaccgaggtgctacccccgccgccggaggaggagggcggtgtcggcgccaagaag
ggcaagaagccgaccggccccaagccgcgcaccggctcgctgctgcggtcgatggacctg
cagaccgtgacgctcgaggatgccctcaaactcatttcgctgccgcgggttgtcggcgtg
gatcccgccaacggcgaggagatcaccgcgcagaacggccgctatggcccgtacctcaag
cgcggcaccgactctcgctcgctggccaccgaggaccagatcttcgacatcacccttgaa
gaggccctgaagatctacgccgagcccaaacgcggtggccgccagggcgctgccgctccg
ccacttcgggaactgggcgtcgatgcggcgtcgggccagccgatggtgatcaaggatggc
cgcttcggtccttacgtcaccgacggtgagaccaacgccagcctgcgcaagggcgatgac
gtcctgtcgatcaccgatgagcgtgcttcggagctgctcgccgaccggcgcgctcgtggc
ccggtcaagaagaaggctcccgcgaagaaagcggcgcgtaagaaggcccccgccaagaag
gcgtga
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