Mycolicibacterium helvum: MHEL_37570
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Entry
MHEL_37570 CDS
T07064
Symbol
bkdA
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00280
Valine, leucine and isoleucine degradation
mhev00640
Propanoate metabolism
mhev00785
Lipoic acid metabolism
mhev01100
Metabolic pathways
mhev01110
Biosynthesis of secondary metabolites
mhev01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MHEL_37570 (bkdA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MHEL_37570 (bkdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MHEL_37570 (bkdA)
Enzymes [BR:
mhev01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MHEL_37570 (bkdA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
TPP_enzyme_C
DXP_synthase_N
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
BBY65514
UniProt:
A0A7I7T8B7
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All DBs
Position
complement(3999569..4001560)
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AA seq
663 aa
AA seq
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MSTHPFSAAQAYRQMALIRRFEEQILDLGREGVIAGSIHLCLGQEAIPVGALAALQEQDR
VLSTYRGHGWALACGTDPEALMAEIAQRGNGVNGGRAGSPLLSDPDHGFLGENSIVGAGV
PIADGVALASQYLGTNRVVVTSVGDGAMNQGATTEGMIFAAARNLPVIFLCENNGWAEMT
AISGINRVPDLAERSHGLGIESHVVDGNDPFAVYEAVGAAAAKCRSGEGPILLECKTSRL
SGHYNKDIQHYRPEADADAARAADPLPRLILRALDEGALTEDEIDDIDEQVYKLIDSIAQ
RVRTAPDPVVADVYTHVLAPDTTSDTRPTSPVEPAKELSYLRAINLALRTEMDNRPEVAI
WGEDVGFAGGIFGVTRGLQKDYGERRIFDTPIAEAAILGAAVGAAMEGMRPVVEIMWADF
LFVALDQIINQAANVRYVSRSRLTAPMVVRMQQGVTPGSCAQHSQSIEAILAHIPGIKVG
LPATAQDAYSMTRAAIADPDPTILIEHRSLYQETGSVTAGGEVQAAAGARKHRDGSDLAI
ITWGSMLHEALSAADDLALNGIHASVLDLRWLRPLDDAAIADVVRAAGGRVVVAHEANLT
AGFGAEIAAHITERHFDILAAPVSRIGLNDLRMPSAPVLQAAVLPRAADIVDAARKLVTP
AHV
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
gtgagtactcatcctttttctgcggcgcaggcctatcggcagatggccctcatccgccgg
ttcgaagaacagatcctcgatctcggccgtgaaggcgtcatcgctggttcaatccatctg
tgccttggccaggaggccattcccgtcggagcccttgctgctctgcaggaacaagatcgg
gtgctgtcgacctatcgaggacacggctgggccttggcgtgcggcaccgacccagaagca
ttgatggccgaaattgcgcagcgcggcaacggagttaacggcggccgagccggctccccc
ttgctgagcgatcccgaccacggattcctcggtgagaactccattgtcggagccggcgtt
ccgatcgctgatggagtggcgttggcctcccagtacctgggtaccaatcgcgtcgtggtg
acctcggtcggcgatggcgccatgaatcagggcgcgacgaccgaaggcatgatctttgct
gcggcacgcaatctgccggtcattttcttgtgcgagaacaacggctgggccgagatgacc
gccatttccggaatcaaccgggtgcccgatctggccgagcgcagccacgggctcggcatc
gaaagccacgtcgtggacggcaacgaccccttcgcggtgtacgaggcggtcggggcggcc
gcggcgaagtgccgatccggcgagggcccaattcttctggaatgcaagacctcccgactg
tcgggacattacaacaaggacatccagcactaccgccccgaggcggacgctgacgccgcc
cgagccgctgacccactcccccgactgatcctgcgtgccctcgacgaaggcgcactgacc
gaggatgagatcgacgatatcgacgagcaggtctacaaactcatcgactccatcgcccag
cgtgtacgaaccgcgccggaccccgtcgtcgccgacgtctacacgcacgtgctggcaccc
gacacaaccagcgacacaaggccgacaagcccagtggaaccggccaaagagctcagctac
ttgcgggcaatcaacctcgcactgcgcacggagatggacaaccgccccgaggtcgccatc
tggggcgaagacgtcggatttgccggcggcatcttcggcgtgactcgcggtctgcagaaa
gactacggagagcgtcgcatcttcgacactccgatcgccgaagcggcgatcctgggcgcc
gctgttggcgcggccatggaggggatgcgcccggtcgtggaaatcatgtgggccgacttt
ctcttcgtcgcgctcgatcagatcatcaaccaagcagccaatgtgcggtacgtcagccgc
tcacggctcaccgccccgatggtcgtgcgcatgcagcaaggtgtcacgcccggatcgtgc
gctcagcactcgcagagcatcgaggccattctggcgcacatcccgggcatcaaggtcggc
ttgcccgccaccgcccaggacgcatattccatgacccgcgcagccatcgccgaccccgac
ccgacaatcctcatcgaacaccgcagcctctaccaagaaacgggatcggtgacagccggt
ggcgaggtgcaggcagcggccggcgcacgcaagcaccgtgacggctccgatctggcgatc
atcacctggggctccatgctgcacgaagcgctctcggctgctgatgatctagcgctcaac
ggcattcacgcgtccgtgctcgatctgaggtggttgcgtcccctcgacgacgcagcgatc
gcggacgtcgtgcgcgccgccggcggacgtgtcgtggtcgcacacgaagccaatctcacc
gcaggtttcggtgccgagattgccgcccacatcaccgaacggcatttcgacatcctggcc
gcgccggtttcccggataggcctcaacgatctacgcatgccctcagcgcccgtcctgcaa
gccgcggtattgccacgcgccgccgacatcgtcgacgctgcacgcaaactggtgacacca
gcacacgtctga
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