Mycolicibacterium helvum: MHEL_38490
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Entry
MHEL_38490 CDS
T07064
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00270
Cysteine and methionine metabolism
mhev00450
Selenocompound metabolism
mhev01100
Metabolic pathways
mhev01110
Biosynthesis of secondary metabolites
mhev01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MHEL_38490 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MHEL_38490 (metE)
Enzymes [BR:
mhev01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
MHEL_38490 (metE)
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Gene cluster
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Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
BBY65606
UniProt:
A0A7I7TBT0
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Position
complement(4105350..4107590)
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AA seq
746 aa
AA seq
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MGSPRIGPNRELKRAIESYWAGRTDKAQLESVAAELRKQTWAELAAAGLDSVPVNTFSYY
DHMLDTAVLVGALPARYSAVSDEVDRYFAAARGTAELAPLEMTKWFDTNYHYIVPEIGPG
TQFALNPTKVIAELEEAQALGISARPVIVGPLTFLALSKAVDGGAVPISRLDELVAVYAV
LLSTLANHGAEWVQFDEPVLATDILDNAADLARHTYSVLGDLSYRPAIFVATYFGELTDA
LTSLAGTPVEAIGVDLVAGSAATVAAVPALTNKTVVAGIVDGRNVWRTDLESALGTLEKL
RESAAHVAVSTSCSTLHVPYTLAAESDIDAALRSWLAFGSEKVIEVATLARALREGREAV
AAAIDEATAAIASRKSDPRLRNGDVRARLASILAGGRTRGPAAARRESQNARLNLPALPT
TTIGSYPQTVEIRKARAALVAGELDQNEYTNRMKAEVESVIRLQERLGIDVLVHGEPERN
DMVQYFAEQLDGFFATVNGWVQSYGTRCVRPPILYGDVARPKPMTVDWATYAQSLTDKPV
KGMLTGPVTILAWSFVRDDQPLSETAAQVALAIRDETVDLEAAGIAIIQVDEPALRELLP
LRREDKDAYLDWAVSSFRLSTSGVADSTQIHTHLCYSEFGEIIGAIADLDADVTSVEAAR
SHMEIVEDLTAAGFANSIGPGVYDIHSPRVPDTGEIADGLRAALSAVGPERLWVNPDCGL
KTRKTDEVEAALHNMVEAAKQVRAGA
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
ttgggatcgccgcggatcgggcccaaccgcgaactcaagcgggccatcgagagctactgg
gccggccgcacggacaaggcccagctggaatcagtggccgctgagctgcgcaagcagacc
tgggccgagctcgccgccgccggcctggattccgttccggtcaacacgttctcctactac
gaccacatgctggacaccgcggtcctggtgggcgcactgcccgcccggtacagtgcggtc
agcgatgaggtggaccgctacttcgcggctgcccgtggtacggcagagcttgcccccctg
gagatgaccaagtggttcgacaccaactaccactacatcgttccagagatcggtcccggt
acgcagtttgcgctcaatcccacaaaggtaattgccgagttggaagaagctcaggcgctg
gggatttcagcacgcccggtcatcgtggggccgctcaccttcctggcgctgtcgaaggca
gtcgacggaggtgcagtgccgatcagccggctcgacgaactcgtcgctgtgtacgcagtt
ctcctcagcacgttggcaaaccacggtgcagagtgggtccagttcgacgagccggtgcta
gccaccgacatccttgacaacgcagccgatctcgcgcgacacacctacagcgtcctcggc
gatctgtcgtaccgtccggccattttcgtggcaacatacttcggcgaactcaccgatgcc
ttgacctcccttgccggcacccccgttgaggcgatcggcgtcgatctggtggccggctca
gccgccaccgtcgccgctgtgccggcactgacgaacaagaccgttgtcgcgggcatcgtt
gacgggcgcaacgtctggcgcaccgacctcgagtccgcacttggcacgctcgaaaaactg
cgcgaatcggcggcccatgttgcggtttccacatcgtgctcaaccctgcatgtcccatac
accctcgccgcggagtccgatatcgacgcggccctgcgcagctggctggccttcggatcc
gagaaagtcatcgaggtcgcgacgctggcccgtgcgctgcgggaaggccgcgaggcagtc
gccgccgccatcgacgaggccaccgccgcgattgcatcccgcaaatcggatccccggctg
cgcaacggcgatgtccgggcacggctggcatcgatcctggccggcggccggacccgcggc
cctgccgctgctcgccgggagagccagaacgcacggctcaacctgcccgcgctgccgaca
actaccatcggttcgtacccgcagaccgtcgagatccgcaaggcccgggcagcgctagtg
gccggtgagctcgatcagaacgagtacaccaaccggatgaaagccgaagtggagtcggtc
attcggctgcaggagcggctcggtatcgacgtgctggtgcacggcgagccggaacgcaac
gacatggtgcagtacttcgccgagcaactcgacggcttcttcgccacggtcaacggctgg
gtccagtcgtacggcactcgctgcgtgcgcccgccgatcctctacggggatgtcgcccgc
cccaagccgatgacggtggactgggccacctacgcgcagtcactgaccgacaagccggtc
aagggcatgctgaccggaccggtgaccatcctggcgtggtcctttgtgcgcgacgatcaa
ccactatccgagacggctgcccaagtggcgctggccatccgggacgagacggtggatctg
gaggccgccggaatcgcgatcatccaggtcgacgagccggcattgcgtgagttacttccg
ttgcggcgcgaggacaaagacgcctacctggactgggcggtgtcatcgttccggttgtcg
acatcaggtgtcgcggactccacccagatccacacgcatctgtgctactccgagttcggc
gagatcatcggggcgatcgctgacctggatgccgacgtgacatcggtggaagccgcacgg
tcgcacatggagatcgtcgaagatctgacggccgcaggtttcgccaacagcatcgggccc
ggcgtctacgacatccactcgccgcgggtacccgataccggggagatcgccgacggactg
cgagcggcattgtcggcggtgggtccagagcggctgtgggttaacccggactgcggtctg
aagacccgcaagaccgacgaggtcgaagccgcactacacaacatggtcgaagcggccaag
caggtccgcgccggcgcctga
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