Mycolicibacterium helvum: MHEL_42720
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Entry
MHEL_42720 CDS
T07064
Symbol
ddl
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00470
D-Amino acid metabolism
mhev00550
Peptidoglycan biosynthesis
mhev01100
Metabolic pathways
mhev01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
MHEL_42720 (ddl)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MHEL_42720 (ddl)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MHEL_42720 (ddl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mhev01011
]
MHEL_42720 (ddl)
Enzymes [BR:
mhev01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
MHEL_42720 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:
mhev01011
]
Precursor biosynthesis
Amino acid ligase
MHEL_42720 (ddl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_3
RimK
CPSase_L_D2
ATP-grasp_4
ATPgrasp_ST
GARS_A
Motif
Other DBs
NCBI-ProteinID:
BBY66029
UniProt:
A0A7I7TC51
LinkDB
All DBs
Position
4547704..4548828
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AA seq
374 aa
AA seq
DB search
MTSRLPSDRPRIRVAVIYGGRSSEHAISCVSAGSILRNLDPERFEVVAVGITPQGSWVLT
DGSPETLAIADRQLPEVTGESGTALALAADPLRRGELVSLGQTPGQMLTAVDVVFPVLHG
PYGEDGTIQGLLELAGVPYVGAGVFASAAGMDKEFTKKLLAAAGLPIGDHVVLRAQQNAL
TLDEIERLGFPMFVKPARGGSSIGVSRVANADELAAAIADARRHDPKVIIEAAIPGRELE
CGVLEFPDGSVQASAIGEIRVAPVLGRDDGFYDFATKYLDDGAELDVPAKVDDDVAEELQ
RLAIQTFKALDCQGLARVDFFLTDDGPVVNEINTMPGFTTISMYPRMWAASGIDYPTLVS
TMVETALARGTGLR
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
gtgacttcccgcctgccgtcggaccggccccggatccgcgtcgctgtcatctatgggggc
cgcagctccgagcacgcgatttcctgtgtgtcggcgggcagcatcctgcggaatctcgac
ccggagcgtttcgaggtcgtcgccgtcggcatcaccccgcagggctcgtgggtgctgacc
gacggcagtccagagaccctggccatcgccgaccggcaactgcccgaggtcaccggcgag
tcgggcaccgcgctggcgttggcggccgatccgctgcgccgcggggagctggtgtcgctc
gggcagactcccggtcagatgctgacggcggtcgacgtggtcttccccgttctgcacggt
ccctacggtgaagacggcacaatccagggcctgttggaattggcgggggtgccctacgtg
ggcgccggggtgttcgccagcgccgcgggcatggacaaggaattcaccaagaagctactg
gccgccgccgggctgccgatcggcgatcacgttgtgttgcgcgcacagcagaatgcgttg
acgctggacgagattgagcgactgggctttccgatgttcgtcaaaccggcgcgcggtgga
tcgtcgatcggggtgagtcgggtcgccaacgctgacgagctcgctgctgcgatcgccgat
gcccgccgccacgatccgaaagtgatcatcgaggccgctatcccgggccgcgagctcgaa
tgcggagtgctcgaattcccggacggctcagtgcaagccagcgccatcggtgagatccgg
gtggctccagtcttgggccgcgatgacggcttctatgacttcgccaccaaataccttgac
gacggcgccgaactcgacgtgccggccaaggtcgacgacgacgtcgcagaagaattgcag
cgcttggcgattcagacgttcaaggcgctggactgccagggcctggcccgggtggacttc
ttcctcaccgacgacggcccggtggtcaacgagatcaacaccatgcccggcttcacgacg
atctcgatgtacccccggatgtgggccgccagcggcatcgactacccgacgctggtgagc
accatggtcgagaccgccctggcccgcggaaccgggctgcgctga
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