Mycolicibacterium helvum: MHEL_45130
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Entry
MHEL_45130 CDS
T07064
Symbol
thyX
Name
(GenBank) flavin-dependent thymidylate synthase
KO
K03465
thymidylate synthase (FAD) [EC:
2.1.1.148
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00240
Pyrimidine metabolism
mhev00670
One carbon pool by folate
mhev01100
Metabolic pathways
mhev01232
Nucleotide metabolism
Module
mhev_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
MHEL_45130 (thyX)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MHEL_45130 (thyX)
Enzymes [BR:
mhev01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.148 thymidylate synthase (FAD)
MHEL_45130 (thyX)
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Gene cluster
GFIT
Motif
Pfam:
Thy1
Motif
Other DBs
NCBI-ProteinID:
BBY66270
UniProt:
A0A7I7TBD1
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All DBs
Position
4803709..4804461
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AA seq
250 aa
AA seq
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MAETAPLRVQLIAKTEFLAPADVPWSTDADGGQALVEFAGRACYQSWSKPNPRTATNAAY
LKHVIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPENDAQVVVPP
GLEDDPELRQILLEAADASRAAYLELLTRLEAKFADQPNAVLRRKQARQAARAVLPNDTE
TRIVVSGNYRAWRHFIAMRASEHADVEIRRLAIACLRQLADVAPAVFADFQISELADGTE
VATSPLATEA
NT seq
753 nt
NT seq
+upstream
nt +downstream
nt
gtggccgagaccgcgccgctgcgcgtgcagctgatcgccaagaccgagttcctggcgcct
gccgacgtgccatggagcaccgacgccgacggtggccaggcactcgtcgaattcgccggc
cgtgcctgctatcagagctggtccaagccaaatccccggacggccaccaacgcggcctac
ctcaaacacgtcatcgacgtggggcacttttcggtgctcgagcatgcctcggtgtcgttc
tacatcaccggcatctcccggtcttgcacgcacgagctgatccggcaccggcacttttcc
tactcccagctgtcccagcggtacgtgcccgagaacgacgcccaggtggtcgtgccgccc
ggtctggaagacgacccggagctgcgccagatcctgctcgaggccgccgacgccagccgc
gccgcctacctggagctactgacccggctggaggccaagttcgccgatcagcccaacgcc
gtgctgcggcgcaagcaggcccgtcaagcggcacgcgctgtgctgcccaacgacaccgag
acccgcatcgtcgtcagcggcaattaccgagcttggcggcacttcatcgccatgcgggcc
agcgaacacgccgacgtggagatccgccggctggcgatcgcctgcctgcgtcagctcgct
gacgttgcccccgccgtcttcgccgacttccagatcagcgaacttgccgacggcacggaa
gtggcgacgtccccgctggctacggaggcctaa
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