Mycolicibacterium helvum: MHEL_45880
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Entry
MHEL_45880 CDS
T07064
Symbol
dxs
Name
(GenBank) 1-deoxy-D-xylulose-5-phosphate synthase
KO
K01662
1-deoxy-D-xylulose-5-phosphate synthase [EC:
2.2.1.7
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00730
Thiamine metabolism
mhev00900
Terpenoid backbone biosynthesis
mhev01100
Metabolic pathways
mhev01110
Biosynthesis of secondary metabolites
Module
mhev_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
MHEL_45880 (dxs)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
MHEL_45880 (dxs)
Enzymes [BR:
mhev01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase
MHEL_45880 (dxs)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
DXP_synthase_N
Transket_pyr
Transketolase_C
PFOR_II
TPP_enzyme_C
E1_dh
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
BBY66345
UniProt:
A0A7I7TDB7
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All DBs
Position
4871583..4873499
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AA seq
638 aa
AA seq
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MLEQVRGPADLQHLSQAQLTDLAAEIRQFLIHKVAATGGHLGPNLGVVELTLALHRVFDS
PHDPILFDTGHQAYVHKMLTGRAADFDTLRKREGLSGYPSRAESEHDWVESSHASAALSY
ADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAAARRPVVIVVNDNGRSYAPT
IGGLADHLAGLRLQPGYERFLERGRVAVRGVPVVGEACYQAMHSVKAGIKDALSPQVMFT
DLGLKYVGPIDGHDEHAVETALRHARGFNAPVIVHVVTRKGMGYAPAENDEAEQMHSCGV
IDPDTGLATKSSAPGWTSVFSESLISYAAKRRDIVAITAAMPGPTGLSAFGERFPDRLFD
VGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQVMMDVALHKLPVTMVLDRAGITG
NDGASHNGMWDLSLLNIVPGIQVAAPRDGARLTEELGEALEINDGPTAIRFPKGEVGEDI
PALERISGIDILARPTDGLGNDVLLVAVGSFASMALKVAQRLRNQGIGVTVVDPRWVIPV
PDAVAPLAESHKLVVTLEDNGVRGGVGSTVSATLRAAEIDVPCRDVAVPQQFLDHAARGE
VLESVGLTEQHIARQVTGWVAALGALDADEHQTSEHLD
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgctcgaacaggttcgcggcccagccgatttgcaacacctgtcccaagcgcagctgacc
gatctggccgccgagattcgccagttcctgattcacaaggtcgcggccacgggcggacac
ctcgggccgaacctcggtgtcgtcgagctgacgctggcgctgcaccgggtcttcgactct
ccgcacgaccctatccttttcgacactgggcaccaggcctacgtccacaagatgctcact
ggccgcgcggccgactttgacacgctgcgcaagcgagagggcctgtcgggctacccgtct
cgcgccgaaagcgagcacgactgggtcgagtccagccacgcctcggcggcactgtcctac
gccgacgggttggccaaggccttcgagctgaccggccatcggaaccgccatgtggtagcg
gtggtcggcgacggcgccctgaccggcggcatgtgctgggaggcgctgaacaacatcgcc
gccgcccgccgcccggtggtgatcgtcgtcaatgacaacggccgctcctacgccccgacc
atcggcgggctggccgatcacctggccgggcttcggctgcagccgggttacgaacgattc
ctggagcgcggccgggtggcggtgcgcggcgtgccggtcgtcggcgaggcctgctatcag
gccatgcacagcgtgaaagccggcatcaaggacgcgctgtctccgcaggtgatgttcacc
gaccttggcctgaagtacgtgggcccgatcgacgggcatgacgagcacgcggtggagacc
gccttgcggcacgccagaggcttcaacgccccggtgatcgtgcacgtggtgacccgcaag
ggcatgggctatgcgccggccgagaacgacgaggccgagcagatgcattcctgcggggtg
atcgaccccgacaccgggctggcgacgaagtcctcggcgcccggctggacctcggtgttc
tccgaatcactgatctcttatgccgccaagcggcgcgacatcgtggcgatcaccgcggcg
atgcccggcccgaccggtttgtcggcgttcggggaacgcttcccggaccggctgttcgac
gtcgggatcgccgagcagcatgcgatgacctcggcggcgggcctggcgatgggtgggctg
cacccggtggtggccatctattcgacgttcctcaaccgcgcgttcgaccaggtgatgatg
gacgttgctctgcacaaactcccggtcaccatggtgctcgatcgggccgggatcaccggc
aatgacggcgccagccataacggtatgtgggacctgtcgctactcaacattgttcccggc
atccaggtggccgcgccgcgtgacggcgcccggctgaccgaggagctgggtgaggcgctg
gagatcaacgacggcccgactgccattcgcttccccaaaggtgaagtgggcgaggacatt
cccgcgctcgaacggatctcgggtatcgatatcctggcacgtccgaccgacggtctcggt
aacgatgtgctgctcgtcgcggtgggatcgttcgcgtcgatggcgctcaaagtcgcccag
cggctgcgcaatcaggggatcggtgtgaccgtcgtcgatccgcgctgggtgattccggtg
cccgatgcggttgcgccccttgccgagtcgcacaagctggtggtcacgctggaggacaac
ggcgtgcgcggtggggtgggttcgacggtctcggctacgctgcgcgccgccgagatcgat
gttccctgccgggatgtggctgtgccgcaacagttcttggaccatgccgcgcgcggcgag
gtgctcgaatcagtgggcttgaccgagcagcacatcgctcgtcaggtcaccgggtgggtg
gccgcgctgggcgcgctcgatgctgacgagcatcagaccagcgaacacctcgactag
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