Mycolicibacterium helvum: MHEL_58420
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Entry
MHEL_58420 CDS
T07064
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mhev
Mycolicibacterium helvum
Pathway
mhev00300
Lysine biosynthesis
mhev00550
Peptidoglycan biosynthesis
mhev01100
Metabolic pathways
mhev01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhev00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MHEL_58420 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MHEL_58420 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MHEL_58420 (murF)
Enzymes [BR:
mhev01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MHEL_58420 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6707
Motif
Other DBs
NCBI-ProteinID:
BBY67599
UniProt:
A0A7I7TGV8
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All DBs
Position
complement(6177668..6179143)
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AA seq
491 aa
AA seq
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MIALTVAQIAEIVGGVLTDISPEEAARRVVTGTVEFDSRAVTPGGLFLALPGARSDGHDF
ARGAVDAGAAAVLAARPVGVPAIVVPPASAADAGAGVLEHDVDGSGAAVLAALAKLATAV
AAELVAGGLTIVGVTGSSGKTSTKDLIAAVLRPLGEVVAPPGSFNNELGHPWTVLRATTD
TDYLVLEMSARHPGNIAALAAIAPPSIAVVLNVGTAHLGEFGSREIIAATKGELVEAVPD
SGVAILNADDPMVAAMAQRTAARVVRVGRSESADIRAVDVELDDLARPRFLLVCAAGTAD
VQLAVHGEHQVGNALSAAAVALECGATPEQAAAALASAGPASRHRMEVHTRGDGVTVVND
AYNANPDSMKAGLQALAVMARRQNKRSWAVLGEMAELGDSSITEHDRVGRLAVRLDISRL
VVVGTGRPMNAMHHGAVMEGSWGSESTMVDDADAALELLRAELAPGDVVLVKASNAAGLG
ALAEALVGDPA
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcgctgaccgtcgcccagatcgccgagatcgtcgggggagtgctcaccgacatc
agtcccgaggaggccgcccggcgggtggtcaccggcaccgtcgagttcgactcgcgggcc
gtcaccccgggcggactgtttctggcgttgcccggtgcgcgttccgacggccacgacttc
gccaggggcgccgtcgatgccggcgccgcggcggtgctcgccgcgcgcccggtcggggtg
cccgcgatcgtcgtgccgccggcgtcggccgccgacgccggcgccggggtgctcgagcat
gacgtcgacggctctggtgcggccgtgctggccgcgctggccaaactcgccaccgcggtg
gccgccgaactcgtcgccggcgggctgacgatcgtcggggtcaccggatcgtcgggcaag
acgtcgacgaaagatctcattgccgcggtgctgcgcccgttgggcgaggtggtggccccg
ccgggttcgttcaacaacgagttggggcatccgtggaccgtgctgcgcgcgaccacggac
accgactatctggttctcgagatgtccgcgcgtcatcccggcaacatcgccgcgctggcc
gcgatcgccccgccgtcgatcgcggtggtgctcaacgtcggcaccgcccaccttggcgag
ttcggttcgcgcgagatcatcgcggccacgaaaggcgaactggtagaagcggttccggac
tcaggagttgcgattctcaacgccgacgacccgatggtggccgccatggcgcagcgaacc
gccgcgcgggtggtcagggtcgggcggtccgagagcgccgacatccgcgccgtggacgtc
gaactcgacgatctggcccggccccgctttctgttggtgtgcgcggccggcaccgcagat
gtgcaactggccgtgcacggtgagcatcaggtcggtaatgcgctgagcgcggccgcggtg
gcgctcgaatgcggggcgacacctgagcaggcggccgccgcgctggccagcgccggcccg
gcgtcgcggcatcgtatggaggtgcacacccggggcgacggggtgaccgtcgtcaacgac
gcgtacaacgccaaccccgactcgatgaaggccggtctgcaggcgctggcggtgatggcg
cggcgccagaacaagcgcagttgggccgtgctcggcgagatggccgagctgggggactcc
tcgattaccgagcatgatcgtgtcggccgactcgcggtgcgcttagatatcagtcgactc
gtcgtcgtcggaaccgggaggcccatgaacgccatgcatcacggcgctgtcatggaggga
tcctggggttcggaatccaccatggtcgacgacgccgacgctgccctggaattgctgcgc
gccgagttggcgcccggtgacgttgtcttggtcaaggcgtcgaacgccgccgggctgggg
gcactggcagaagcgctggtgggtgacccggcatga
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