Mycolicibacter hiberniae: MHIB_11850
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Entry
MHIB_11850 CDS
T06801
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mhib
Mycolicibacter hiberniae
Pathway
mhib00300
Lysine biosynthesis
mhib00550
Peptidoglycan biosynthesis
mhib01100
Metabolic pathways
mhib01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhib00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MHIB_11850 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MHIB_11850 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MHIB_11850 (murF)
Enzymes [BR:
mhib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MHIB_11850 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBZ22767
UniProt:
A0A7I7X1Q5
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Position
1277301..1278833
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AA seq
510 aa
AA seq
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MIALTVAQVAEIVGGRLADITPEKAERTIVTGTVEFDSRRITPGALFLALPGARSDGHDH
AASAVEAGAVAVLAARPVGVPAIVVSPGDAASDSRSGALEHDDPAGSGAAVLAALAKLAA
AVSATLVAGGLKIIGVTGSSGKTSTKDLIAAVLAPLGEVVAPPGSFNNELGHPWTVLRAD
ESTDFLVLELSARHRGNIAALAAIAPPQIAVVLNVGTAHLGEFGSREAIAQTKAELVQAV
PESGVAILNVDDSAVAAMADQTVARVVRVSRSAPADVWAGPVVLDELARPRFTLHYGPQG
ANGVAVALGVSGDHQVSNALCAAAVARECGATPQQVADALAGAGPASRHRMQVSTRADGV
IVIDDSYNANPDSMRVALQALAWIARTEPAPGSPTPAGRRRSWAVLGEMAELGEDAISEH
DRIGRLAVRLDVSRLIVVGVGRSMGAMLHGAVMEGSWGAEATAVPDVDAALALLRAELQA
GDVVLVKASNSAGLTALAQALAADDAGERR
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcgctgaccgtcgcgcaggtcgccgagatcgtcggcggacggctggccgacatc
acccccgagaaggccgagcgcaccatcgtcaccggcacggtggagttcgattcccgccgg
atcaccccgggcgcgctgttcctggccctgcccggtgcccgctccgacggtcacgaccac
gcggcgtcggcggtcgaggccggcgcggtggcggtgttggcggcgcgcccggtcggcgtg
ccggccatcgtggtcagtcccggagatgcggcctccgacagccgatccggtgccctcgaa
cacgacgacccggcgggatccggtgccgcggtgctggccgcgctggccaaactggccgcc
gcggtctcggccaccctggtcgccggcgggctgaagatcatcggcgtgaccggctcctcg
ggcaagacctcgaccaaggatctgatcgccgcggtgcttgcgccgctgggcgaggtggtc
gcgccgcccgggtcgttcaacaacgagctggggcatccctggacggtgctgcgggccgac
gagagcaccgacttcctggtgctggagctctcggcgcgtcatcgcggcaacatcgcggcg
ctcgcggcgatcgccccgccgcagatcgcggtggtactcaacgtcgggaccgcgcacctg
ggtgagttcggttcgcgcgaagcgatagcccagaccaaagccgaactggtccaagctgtt
ccagagtccggtgtggcgatcctcaacgtcgacgactccgcggttgcggcgatggccgac
cagactgtggcccgggtggtgcgggtcagccgttcggctccggccgatgtctgggccgga
ccggtggtgctcgacgagctggctcgtccgcggttcaccctgcactacgggccccagggt
gcgaacggcgtcgccgttgcgctcggggtctccggcgatcaccaggtgagcaacgcgctg
tgtgccgcggcggtcgcccgcgaatgcggcgccacgccgcaacaggtggccgacgccctg
gccggggccggaccggcctcgcgacaccggatgcaggtcagcacccgcgcggacggcgtg
atcgtgatcgacgactcctacaacgccaacccggattccatgcgggtggcgctgcaggcg
ctggcctggatcgcccgcacggagccggcgcccggttcacccacgcccgccggcaggcgg
cgcagctgggcggtgctcggcgagatggccgagctgggcgaggacgcgatatctgagcat
gaccgcatcggacggctcgcggtgcgcttagatgtgtctcgtctcattgtcgtcggagtt
gggagatcgatgggcgcgatgctgcacggcgcggtcatggagggttcgtggggcgccgag
gccactgcggtccccgacgtcgatgccgccctggccctgttgcgcgccgaactacaggcc
ggagacgtggtgctggtcaaggcgtcgaactccgccgggctgactgcgctggcgcaggca
ctggccgccgatgacgcaggagagcgccgatga
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