KEGG   Megasphaera hexanoica: ACT01_06385
Entry
ACT01_06385       CDS       T05536                                 
Name
(GenBank) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
mhw  Megasphaera hexanoica
Pathway
mhw00670  One carbon pool by folate
mhw00720  Other carbon fixation pathways
mhw01100  Metabolic pathways
mhw01120  Microbial metabolism in diverse environments
mhw01200  Carbon metabolism
mhw01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:mhw00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    ACT01_06385
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ACT01_06385
Enzymes [BR:mhw01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     ACT01_06385
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     ACT01_06385
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C Shikimate_DH OCD_Mu_crystall Viral_env_E26
Other DBs
NCBI-ProteinID: AXB81890
UniProt: A0A848BZ27
LinkDB
Position
1370309..1371148
AA seq 279 aa
MLLLDGKAVAAFHRERVESKIYDFQEQHIRPELAIVLAGQDKPSAMYASSMQRVARNVGL
SAEIYRLSESVSERDIISMLEHFNEQKHIFGILMMMPLPHHLNASRIINCISPDKDVDGL
TDTNIARLFSGRSGFVPCTPRAVMAILDYYHISLTGKDVVIIGRSNVVGKPLAQLCLNRN
ATVTHCHTRTHDLKAAARRADILISAAGAPGLITADMVKPGAVVIDVGINRVDGKTVGDV
DFEGVSQVAGALTPVPGGVGAVTTMMVLENVVCRGAWTD
NT seq 840 nt   +upstreamnt  +downstreamnt
gtgttattgttagatgggaaggctgtagcagcctttcatcgtgagagggtagagagcaaa
atttacgatttccaggaacaacatatccggccggaactggctatcgtcctggccggtcag
gataagccctcggcgatgtatgcctcttcgatgcagcgcgtagcccgcaacgtcggatta
tccgctgaaatttaccgtttgtccgaatcggtaagcgaacgggacatcatttccatgctc
gaacatttcaatgagcagaaacatatttttggcattctcatgatgatgcccctgccgcat
catctcaacgcttcacggatcatcaactgcatcagtcccgataaagacgtagatggactg
accgatacgaatattgcccgcctgttttccgggaggtccggatttgtaccgtgtacaccc
cgtgccgttatggccattctggattattatcacatttcactgacggggaaggatgtcgtt
atcattggccggagcaatgtcgtcggcaagccactggcccagctctgcctgaaccgcaat
gcgaccgttactcattgccatacgcgcacccatgatctgaaagccgcggcacggcgggcg
gatattctgatcagtgccgccggggcgccgggactcataacggccgatatggtcaaaccg
ggagctgtcgttattgacgtaggaatcaaccgcgtcgatggcaagactgtcggcgatgta
gatttcgaaggcgtttcccaggttgcaggggcactgacacccgtgccgggtggcgtaggt
gccgttacgactatgatggttttggaaaacgtagtctgccggggtgcatggacggactag

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