Mannheimia haemolytica M42548: MHH_c26940
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Entry
MHH_c26940 CDS
T02635
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase ThrA
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
mhx
Mannheimia haemolytica M42548
Pathway
mhx00260
Glycine, serine and threonine metabolism
mhx00261
Monobactam biosynthesis
mhx00270
Cysteine and methionine metabolism
mhx00300
Lysine biosynthesis
mhx01100
Metabolic pathways
mhx01110
Biosynthesis of secondary metabolites
mhx01120
Microbial metabolism in diverse environments
mhx01230
Biosynthesis of amino acids
Module
mhx_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
mhx_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mhx_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mhx00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MHH_c26940 (thrA)
00270 Cysteine and methionine metabolism
MHH_c26940 (thrA)
00300 Lysine biosynthesis
MHH_c26940 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MHH_c26940 (thrA)
Enzymes [BR:
mhx01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MHH_c26940 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MHH_c26940 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
DUF1131
DapB_N
DUF4781
Motif
Other DBs
NCBI-ProteinID:
AGK03122
LinkDB
All DBs
Position
2533439..2535895
Genome browser
AA seq
818 aa
AA seq
DB search
MRVLKFGGTSLANPERFMQAAEIIEKAHLADQAAGVLSAPAKITNHLVAIVDKAIAGESF
QSNLSEATEIFHNIINGLYATNNHFAKEALLALVEAELNQIQQVAAEAAQTKSLSDKIAA
TIHCRGEKLSIAMMQAWFEAKGYEVTRIDPVEKLLAHGSYLESSVDIAESTKRVDAGSIP
KKNIVLMAGFTAGNEQGELVLLGRNGSDYSAACLAACLKADVCEIWTDVDGVYTCDPRLV
PDAVCLETMSYQEAMELSYFGAKVIHPRTIGPLVPLNIPCLIKNTGNPDGKGTLIDGNVA
NDNLKVKGITNLDNVAMFNVSGSGMQGMVGMAARVFSTMSKAGISVILITQSSSEYSISF
CVPAKSAEKALAALNTEFAQELSENLLDPIDIIKDLSIVSVVGDGMRTAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPLNKAIEAVKATHKSLFNSKRVVDMFLVGVGGVGSEL
IEQVKQQKEFLAKKDIEIRVCALANSDKMLLNENGLNLDNWKEDLEKAIQPSDFDVLLSF
IKFHHVVNPVFVDCTSAQSVANLYARALKEGFHVVTPNKKANTSGYDYYLEMRENARQSQ
HKFLYETNVGAGLPVIENLQNLLAAGDEVEKFEGILSGSLSFIFGKLEEGLTLSQATLIA
KEKGFTEPDPRDDLSGADVARKLLILVRETGLPLEFEDIEIEGVLPKGFSEGMSRDEFLQ
ALPSLDEEFSKRVEAAKAEGKVLRYVGSITGDKCRVAIEAVDENHPLYKVKDGENALAFL
TRYYNPIPLLLRGYGAGNSVTAAGIFADILRTLQGGVN
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttcttaaatttggaggcacttctcttgccaaccctgaacgctttatgcaagcg
gcagagattatcgagaaagctcatttggcagatcaagctgccggcgtattatccgcccca
gccaaaattaccaatcatcttgtcgctattgtagataaagcgattgccggtgaatcattt
caatctaacctttctgaagctaccgagattttccacaacatcattaacggcttatatgct
acaaataatcactttgctaaagaagcactgttagccttagtggaagcggaattaaaccaa
attcagcaagtggctgcagaagcagctcaaactaaatcgttgtcagataaaattgctgcc
actattcactgccgtggtgaaaaactctctattgcgatgatgcaagcgtggttcgaggca
aaaggctatgaagtcactcgtatcgaccctgttgaaaaattattggctcacggcagctat
ttggaatcttcggtcgatattgccgaatccaccaagcgagttgatgcaggttcaattcca
aagaaaaatatcgtgctaatggctggttttaccgcaggtaatgagcaaggcgaactggtg
ttattagggcgtaacggttcagattattctgccgcttgtttggcagcgtgtttaaaagcc
gatgtttgtgaaatctggacggacgtagatggcgtttacacctgcgaccctcgtttggtg
cctgatgcagtatgcttagaaacaatgagctatcaagaggcaatggagctttcctacttt
ggggcgaaagtgatccaccctcgcaccatcgggccattagtgccgctcaatattccttgt
ttaatcaaaaataccggcaatccggacggaaaaggcacattaattgatggcaatgtggca
aacgataatctcaaagtaaaagggattaccaaccttgataacgtggcgatgttcaacgtt
tcaggttcaggaatgcagggaatggtgggcatggctgcccgtgtgttctcgacgatgtca
aaagccggtatttcggtgattttaattacccaatcatcatcagaatatagcatcagcttc
tgcgtgccggcaaaatcggcagaaaaagcgttagcggctctaaatactgaatttgcacaa
gagttatctgaaaacttacttgacccgattgatattattaaagatttatccattgtttcg
gtagtgggtgatggtatgcgtaccgccaaaggaattgcggctcgcttcttctctgcccta
gcccaagccaacatcagtattgtggcaattgcacagggttcatctgagcgttccatttct
gctgtcgtgccgttaaacaaagcgattgaagcagtaaaagcaactcacaaatcgctattt
aacagtaaacgtgtggtggatatgtttttagtgggtgtaggcggtgtgggtagcgaactc
atcgagcaagtcaaacaacaaaaggagtttttggcaaagaaggatattgagatccgtgtg
tgtgctttagctaattcagataaaatgttactcaacgaaaacggcttaaatttagacaac
tggaaagaagatttagaaaaagcaattcagccgtcagactttgatgtattgctttctttc
atcaaattccaccacgtggtaaacccagtatttgtagattgcacttcggcacaatcggtg
gcgaacctgtacgcacgagccttaaaagagggcttccacgtggtaacaccaaacaaaaaa
gccaatacatcaggttacgattactacttagaaatgcgtgaaaacgcccgccaaagccag
cacaaattcctctacgaaactaatgtaggggcaggtttaccggtaattgaaaacttacaa
aacctattagctgccggtgacgaagtagagaaatttgaagggattttatccggctcgctc
tctttcattttcggcaaattagaagaaggtttaaccctttcgcaagcaactttaatcgcc
aaagaaaaaggctttaccgagccagatccacgagatgatttatccggtgcagatgttgct
cgtaaactcttaattcttgttcgtgaaaccggcttaccgcttgaatttgaagatattgaa
attgaaggcgtattgccaaaaggcttctcggaaggaatgagtcgtgatgagtttttacaa
gctctaccgtctttagacgaagaattcagcaagcgtgtagaagctgccaaggctgaaggc
aaagtgttgcgttatgtgggctcgatcacaggtgataaatgccgagttgccattgaagcc
gtggacgaaaaccacccactttacaaagttaaagacggcgaaaatgcccttgcttttctc
acacgttactacaaccctattccattattattgcgtgggtatggtgcgggcaatagcgta
accgctgccggtatctttgcagatattctgcgtactttacaaggaggagtgaactaa
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