Methanomethylovorans hollandica: Metho_0479
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Entry
Metho_0479 CDS
T02418
Name
(GenBank) isopropylmalate/isohomocitrate dehydrogenase
KO
K10978
methanogen homoisocitrate dehydrogenase [EC:
1.1.1.87
1.1.1.-]
Organism
mhz
Methanomethylovorans hollandica
Pathway
mhz00300
Lysine biosynthesis
mhz00680
Methane metabolism
mhz01100
Metabolic pathways
mhz01110
Biosynthesis of secondary metabolites
mhz01120
Microbial metabolism in diverse environments
mhz01210
2-Oxocarboxylic acid metabolism
mhz01230
Biosynthesis of amino acids
mhz01240
Biosynthesis of cofactors
Module
mhz_M00608
2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
KEGG Orthology (KO) [BR:
mhz00001
]
09100 Metabolism
09102 Energy metabolism
00680 Methane metabolism
Metho_0479
09105 Amino acid metabolism
00300 Lysine biosynthesis
Metho_0479
Enzymes [BR:
mhz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.87 homoisocitrate dehydrogenase
Metho_0479
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AGB48746
UniProt:
L0KUF0
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Position
complement(470222..471220)
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AA seq
332 aa
AA seq
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MKIAVVEGDGIGKEVIPAAIEVLDVLALPVEKVPVELGYAKWEKTGSAITDDDLAVLKEC
DCILFGAITTPSDPTYKSVLLTIRKELDMYANIRPIKPINGIVGVTGRSDFNLVIVRENT
EGMYSGIEELHEDVAYTKRVITRKGSARIADYACKLAKSRQHRLEIAHKSNVLKSDRLFL
DVCRQTASSYHIDHHDTLVDSMAYNLIVHPNRYDVVVTTNLFGDILSDMAAALVGGLGLV
PSANIGKGHAFFEPVHGSAPDIAGKGIANPIAAILSLKMMLEWYELNHQAKLVQDAIEFA
INQNIVTPDLGGISTTREVGNTIAERVKQLIG
NT seq
999 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattgcagttgtggaaggagatgggatcggcaaagaggtcatacctgcagcgata
gaagtactggatgtactcgccctgcctgtggaaaaagtacctgtggaactcggatatgca
aaatgggaaaagacaggctctgctatcaccgatgatgaccttgcagtcctgaaggagtgc
gattgcatcttatttggggctataacaacaccttctgaccctacttataagagtgtactc
cttacaatacgaaaggagcttgatatgtacgctaacattcgtcctataaagcccataaat
ggcattgtgggtgtcacagggcgaagtgattttaacctggtgatcgtgagggagaacaca
gagggcatgtattccggcatagaggagctccatgaagacgttgcatacactaaaagggta
attacccgcaaagggtctgcaaggatagccgattatgcctgcaaacttgccaaaagcagg
cagcatcgcctggaaatagcccataagtccaatgtgcttaaatctgataggttgttcctg
gacgtatgtcgtcagacagcctcttcatatcacatagatcaccacgacaccctagtagat
tccatggcttacaaccttatcgtacaccctaacaggtacgatgtcgtagtgaccactaac
ctgttcggggatatacttagcgatatggctgctgccctggtcgggggacttggactggta
ccaagtgcgaatattggcaaaggacatgcgttctttgagcctgtacacggaagtgcaccc
gatattgccggaaaaggcatagctaaccccatagctgctatcctaagcctgaaaatgatg
ctggagtggtatgaattgaaccaccaggcaaaactggtacaggatgccatagaatttgct
ataaaccagaacatagtcacacctgatctgggaggcatatccacaacaagagaagtagga
aacacaatagcagagcgcgttaaacaacttattggctga
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