Methanomethylovorans hollandica: Metho_2402
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Entry
Metho_2402 CDS
T02418
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mhz
Methanomethylovorans hollandica
Pathway
mhz00290
Valine, leucine and isoleucine biosynthesis
mhz00620
Pyruvate metabolism
mhz01100
Metabolic pathways
mhz01110
Biosynthesis of secondary metabolites
mhz01210
2-Oxocarboxylic acid metabolism
mhz01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
mhz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Metho_2402
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Metho_2402
Enzymes [BR:
mhz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Metho_2402
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
EF-hand_14
Motif
Other DBs
NCBI-ProteinID:
AGB50546
UniProt:
L0KZK7
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Position
2366471..2367982
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AA seq
503 aa
AA seq
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MNKKITIFDTTLRDGEQTPGVSLTNDQKLKIARQLDKLGIDVLEAGFPISSEGDKQSVKA
IANEGLRLDVCGLARVLTKDLDTCLDTGVDMIHTFVSTSDIQRIHTIKKSKEEVLTMAVD
AVQYIKDHGVKCMFSAMDATRTDLDYLTQIYKAVEGAGCDIINVPDTVGIMSPSRMYHLV
GAVSKEIRIPIDVHCHNDFGIAVANSLMAAEAGASQIQVTVNGIGERAGNANLAEVVMCL
QSIYGAKTNINTEYLLETSKMVEKYTGIHMPPNTPIVGENAFAHESGIHTHGVLTKADTF
EPGIMTPEMVGHKRRIVLGKHAGKHAVQKSLEDAGIQTTDEQLDEIVRRIKAIADKGKRI
CDADLHAVAADVLGRNLGSETIKLKELSVMTSNLTTPTAVVRAIVGDEEAVASNIGTGPV
DAAVKAVQQMIAGYTKVKIRDFRIEAITGGADALAEVTIGVEDEDGRVVTAHAASTDIVT
ASVDALITAINILLDKKKLWNMQ
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
ttgaataagaagataactattttcgataccacactgcgcgatggtgaacagacacccggt
gtttccctgacaaatgaccagaagctgaagatcgcaaggcaactggacaagctggggata
gacgttcttgaagccggatttcctatttcttctgaaggagataaacagtctgtaaaagct
atcgctaacgaaggtcttagactggacgtatgtggtcttgcaagagtactaacaaaagac
ctggatacatgcctcgacacaggtgtggacatgatacatacattcgtatccacatctgac
atacagaggatacacacaataaagaagagcaaagaagaagtgctcacaatggctgtggac
gcagtccagtatatcaaggaccatggagtaaaatgcatgttctcagccatggatgccacc
cgtaccgaccttgattatctcacacagatatataaggcagtagagggagcagggtgtgat
attatcaacgtgcctgataccgtgggaataatgtctccttcccgtatgtaccatctggta
ggtgcagtcagtaaggaaataaggattcccatagatgtccactgccacaacgactttgga
atagcagtggctaacagcctcatggctgccgaggctggagcaagccagatccaggtaact
gtaaatggtattggagaaagggccggtaacgccaatcttgctgaagtggtcatgtgcctg
caatcgatctatggtgcaaagacgaacattaatacagaatatctgcttgaaacgtctaaa
atggtcgagaaatatacaggcatacacatgcccccgaacacgcctattgttggcgagaat
gcctttgctcacgagtctggcatccacacccacggagtgctcaccaaggcagacacgttc
gagcccggcatcatgacgccagagatggtaggccacaaaagacgtatcgtactgggtaaa
catgcgggtaagcacgctgtccagaaatcattggaagatgccggcatccagaccactgat
gagcaactggacgaaatagtcaggagaataaaggctatagctgacaaaggaaaaaggatc
tgtgatgctgatctgcatgccgttgcagcagatgtactgggaaggaaccttggcagcgag
accataaagctcaaagagctgtcagtaatgacaagcaacctcacaacaccaactgcagtg
gtcagagccattgttggtgatgaggaagcagttgcatccaacattggtaccggacctgtg
gatgcagccgttaaggcagtacagcaaatgatcgccggatacacaaaggtcaagatacgt
gacttccgcattgaagcgatcaccggaggtgccgatgctcttgccgaggtcactataggc
gtagaggacgaagatggacgtgtggtaacagcccatgctgcaagcaccgacattgtgaca
gcatccgtagacgcacttataacagccataaacatcctgctcgacaagaagaaactatgg
aatatgcagtga
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