Micromonospora sp. HM134: FJK98_23790
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Entry
FJK98_23790 CDS
T06145
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00300
Lysine biosynthesis
mich00550
Peptidoglycan biosynthesis
mich01100
Metabolic pathways
mich01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FJK98_23790
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FJK98_23790
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FJK98_23790
Enzymes [BR:
mich01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FJK98_23790
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Dioxygenase_N
DUF6707
Motif
Other DBs
NCBI-ProteinID:
QDY09795
UniProt:
A0A518WKL3
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All DBs
Position
complement(5526478..5527890)
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AA seq
470 aa
AA seq
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MIPLTLAEVATAVGGRLYAVDPDTRVTGPVEFDSRKVTAGALFVAFPGERVDGHDYAAGA
VTAGAVAVLGTRELPGVPMVLVDDALAALGRLARAVVDRLPGLTVIGLTGSSGKTTTKDL
IAQLAVRLGPTVAPPGSFNNELGHPYTALQATGQTRYLVMEKGARGVGHVRYLCDVVPPR
ISVVLNVGVAHLGEFGSVENIALAKGELVEALPADGLAVLNADDPLVAAMASRTVARVVR
YGESADADVRAVDVTLDGQGRPAYTLVTPEGSAPVRLGLTGRHQVSNSLAAAAVARELGM
PLAELAAALGDLGLVSTRRMDVFTRPDGVTVIDDSYNANPASTAVALRALAGMHRGGRTF
AALGYMAELGAYEDEGHREVGRLAAELGVDRLLVVGEPAAPIHEGATAVSDWGGESVLLT
DQAAAVEVLRSELRPGDVVLVKGSRYRTWEVADALRVDASGDGTGAGGAA
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
gtgatcccgctgaccctggccgaggtggccacggcggtcggcggtcggctgtacgccgtc
gacccggacacccgggtcaccggcccggtcgagttcgactcccgcaaggtcaccgccggg
gcgctcttcgtcgccttccccggcgagcgggtcgacgggcacgactacgccgccggtgcg
gtcaccgccggcgcggtggcggtgctcggcacccgggagctgcccggggtgccgatggtg
ctggtggacgacgcgctggccgcgctgggccggctggcccgcgccgtggtggaccggctg
cccggtctcaccgtgatcgggctgaccggctcgtcgggcaagaccaccaccaaggacctg
atcgcccagctcgccgtccggctcggcccgacggtcgccccgcccgggtcgttcaacaac
gagctggggcacccgtacacggcgttgcaggccaccgggcagacccggtacctggtgatg
gagaagggggcgcggggcgtcgggcacgtccgctacctctgcgacgtggtgccgccgcgg
atctcggtggtgctcaacgtcggggtggcgcacctgggcgagttcggctcggtggagaac
atcgcgctggccaagggggagctggtggaggcgctgccggccgacgggctggcggtgctg
aacgccgacgacccgctggtcgccgcgatggcgtcccgcaccgtggcccgggtcgtccgc
tacggggagtcggccgacgccgacgtccgcgcggtggacgtcaccctggacgggcagggg
cgaccggcgtacaccctggtgaccccggaggggagcgccccggtgcggctcggcctgacc
ggccggcaccaggtctccaattcgctcgccgcggcggcggtcgcccgcgagctgggcatg
ccgctggccgagctggcggcggccctgggtgacctggggctggtctccacccgccggatg
gacgtcttcacccgtcccgacggggtgaccgtgatcgacgactcgtacaacgccaacccg
gcctcgacggcggtggcgctgcgcgcgctggccgggatgcaccggggcgggcggacgttc
gccgcgctgggctacatggccgagctgggcgcgtacgaggacgaggggcaccgggaggtc
ggccggctggcggccgaactcggtgtcgaccggctgctcgtggtgggtgagccggccgcg
ccgatccacgagggcgcgacagcggtaagtgactggggaggagagtcggtgctgctcacc
gatcaggcggcggccgtcgaggtgctgcgcagcgagctacgaccgggcgacgtcgtcctg
gtgaagggctcccggtaccggacctgggaggtcgccgacgcgcttcgggtcgacgcctcc
ggtgacgggaccggcgcggggggtgccgcgtga
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